Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: HFN Versus NIV in Cystic Fibrosis. The HIFEN Study [NA]
The HIFEN Study is a completed clinical trial comparing high-flow nasal oxygen therapy (HFN) versus non-invasive ventilation (NIV) in patien…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: A Study Evaluating Safety and Pharmacokinetics of VX-440 in Combination With Tezacaftor/Ivacaftor in Healthy Adult Subjects [Phase 1]
Phase 1 study assessing safety and pharmacokinetics of VX-440 in combination with Tezacaftor/Ivacaftor in healthy adults has completed.
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Early Signs of Efficacy Study With Riociguat in Adult Homozygous Delta F508 Cystic Fibrosis Patients [Phase 2]
Phase 2 trial update of riociguat in adult homozygous Delta F508 cystic fibrosis patients was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis [NA]
This update notes the completion of an open-label vitamin D trial in patients with cystic fibrosis and allergic bronchopulmonary aspergillos…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Pharmacokinetics of GLPG2737 in Male Subjects With Cystic Fibrosis [Phase 1]
Phase 1 pharmacokinetic study of GLPG2737 in male subjects with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Increased Gluconeogenesis is One Cause of Cystic Fibrosis Related Diabetes (CFRD) [NA]
A completed clinical trial identified increased gluconeogenesis as one of the causes of cystic fibrosis-related diabetes (CFRD).
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CLINICAL_TRIALS trial_result · 2018-03-13Clinical Trial Update: Biomarkers of Iron Homeostasis and Responses to Cystic Fibrosis Pulmonary Exacerbation (CFPE) Treatment
This completed clinical trial update investigates biomarkers of iron homeostasis and responses to treatment during pulmonary exacerbations i…
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CLINICAL_TRIALS trial_result · 2018-03-13Clinical Trial Update: Cystic Fibrosis- Children and Adults Tai Chi Study [NA]
The clinical trial evaluating Tai Chi as an intervention for cystic fibrosis in children and adults has completed.
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CLINICAL_TRIALS research · 2018-03-12Clinical Trial Update: Gaming Console Home-Based Exercise for Adults With Cystic Fibrosis [NA]
The clinical trial evaluating a gaming console-based home exercise program for adults with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Evaluation of Inhaled Antibiotics on Bacterial Diversity and Richness in the Cystic Fibrosis Lung
A clinical trial evaluating inhaled antibiotics for their effect on bacterial diversity and richness in the lungs of people with cystic fibr…
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: RESULT: Reliable, Emergent Solution Using Liprotamase Treatment [Phase 3]
Phase 3 trial update on Liprotamase for exocrine pancreatic insufficiency, including use in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Use of Formula Fortified With DHA in Infants With Cystic Fibrosis [NA]
A completed clinical trial evaluated an infant formula fortified with DHA for infants with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Quantitative Computed Tomodensitometry in Patients With Cystic Fibrosis [NA]
Clinical trial update describing the use of quantitative computed tomography in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-02-23Clinical Trial Update: Safety and Efficacy of Pioglitazone as an Anti-inflammatory for the Treatment of Cystic Fibrosis (CF) Lung Disease [NA]
This clinical trial update evaluates pioglitazone as an anti-inflammatory treatment for cystic fibrosis lung disease. The trial is completed…
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FDA approval · 2018-02-12FDA Approved: SYMDEKO — Original Application (Vertex Pharmaceuticals Incorporated)
FDA approved SYMDEKO (tezacaftor and ivacaftor) as the original application for the treatment of cystic fibrosis. This action represents the…
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CLINICAL_TRIALS trial_result · 2018-02-09Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Efficacy of JBT-101 (Lenabasum) in Cystic Fibrosis [Phase 2]
Phase 2 study evaluating safety, tolerability, pharmacokinetics, and efficacy of lenabasum (JBT-101) in cystic fibrosis; results were posted…
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: Absorptive Clearance After Inhaled Osmotics in Cystic Fibrosis [Phase 1]
Phase 1 trial update on absorptive clearance after inhaled osmotics in cystic fibrosis; study completed with results posted in 2018.
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FDA approval · 2018-01-25FDA Approved: ORKAMBI — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA approved a supplemental application for ORKAMBI (lumacaftor/ivacaftor) from Vertex Pharmaceuticals Incorporated.
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: Cystic Fibrosis and Endothelial Function: At Rest and During Exercise [Phase 2]
Phase 2 clinical trial on cystic fibrosis evaluating endothelial function at rest and during exercise; study completed with results posted i…
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CLINICAL_TRIALS trial_result · 2017-12-13Clinical Trial Update: PTC124 for the Treatment of Cystic Fibrosis [Phase 2]
PTC Therapeutics reports the Phase 2 trial of PTC124 (ataluren) for cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Non-respiratory Comorbidities Observed in Pulmonary French Transplant Patients With Cystic Fibrosis
A completed clinical trial update describes non-respiratory comorbidities observed in French lung transplant recipients with cystic fibrosis…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) [NA]
A completed clinical trial evaluated the efficacy and safety of a combined EGCG and tocotrienol regimen in 18 patients with splicing-mutatio…
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: Assessment of Cystic Fibrosis Lung Involvement With UTE Pulse Sequences [NA]
This report notes the completion of a clinical trial assessing cystic fibrosis lung involvement using ultrashort echo time (UTE) MRI pulse s…
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CLINICAL_TRIALS withdrawal · 2017-11-24Clinical Trial Update: An Investigation of the Association Between Helicobacter Pylori Infection and Abdominal Pain in Cystic Fibrosis Patients
A Penn State University–sponsored trial investigating the association between Helicobacter pylori infection and abdominal pain in cystic fib…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: A Study to Evaluate GLPG2222 in Ivacaftor-treated Subjects With Cystic Fibrosis [Phase 2]
A Phase 2 study evaluated GLPG2222 in cystic fibrosis patients who are already treated with ivacaftor.