Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Effect of Acid Blockade on Microbiota and Inflammation in Cystic Fibrosis (CF)
A clinical trial investigating acid blockade's effects on microbiota and inflammation in cystic fibrosis has been terminated.
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: Prevention of Cystic Fibrosis Diabetes [Phase 3]
Emory University's Phase 3 trial aimed at preventing diabetes in people with cystic fibrosis and prediabetes was terminated; results were po…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation [Phase 3]
Phase 3 study evaluating elexacaftor (VX-661) in combination with ivacaftor in cystic fibrosis patients aged 12+ who are heterozygous for th…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: A Phase 3 Study to Evaluate the Efficacy and Safety of Ivacaftor and VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutation [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of combining ivacaftor with tezacaftor (VX-661) and ivacaftor in cystic fibrosis patients…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor [Phase 3]
Phase 3 randomized, double-blind study evaluating VX-661 (lumacaftor) in combination with Ivacaftor for cystic fibrosis; the trial completed…
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CLINICAL_TRIALS trial_result · 2018-06-11Clinical Trial Update: GLPG2737 on Top of Orkambi in Subjects With Cystic Fibrosis [Phase 2]
Phase 2 trial evaluating the addition of GLPG2737 to Orkambi in cystic fibrosis subjects has completed.
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Lipid Formulation to Increase the Bioavailability of Fatty Acids in Cystic Fibrosis (CF) Patients [NA]
A completed Nestlé-sponsored clinical trial evaluated a lipid formulation intended to increase the bioavailability of fatty acids in cystic …
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CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis [Phase 1]
Phase 1 study of inhaled SNSP113 in healthy subjects and individuals with stable cystic fibrosis was terminated.
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: Effects of Inspiratory Muscle Training on Postural Stability, Balance, Pulmonary Function and Functional Capacity in Children With Cystic Fibrosis [NA]
A completed clinical trial evaluating the effects of inspiratory muscle training on postural stability, balance, pulmonary function, and fun…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: The Effect of Combination Lumacaftor and Ivacaftor on Markers of Hyperglycemia [NA]
A terminated clinical trial evaluating the effect of the lumacaftor/ivacaftor combination on markers of hyperglycemia in cystic fibrosis pat…
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: EASY: Extended Access to Sollpura Over Years [Phase 4]
Phase 4 extended-access study of Sollpura (pancrelipase) in Exocrine Pancreatic Insufficiency and Cystic Fibrosis completed with results pos…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic Fibrosis [Phase 3]
Phase 3 trial SIMPLICITY evaluated liprotamase for malabsorption in cystic fibrosis-related exocrine pancreatic insufficiency; the study com…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Outpatient Antibiotic Treatment for a Cystic Fibrosis Pulmonary Exacerbation
This update notes that an outpatient antibiotic treatment trial for pulmonary exacerbations in cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Capsule Endoscopy in Cystic Fibrosis
The document notes the completion of a clinical trial evaluating capsule endoscopy in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Controlled Ventilation CT in CF Infants
A clinical trial evaluating controlled ventilation CT imaging in infants with cystic fibrosis has been terminated.
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CLINICAL_TRIALS research · 2018-04-23Clinical Trial Update: Predictive Value of PIIINP Urinary for the Development of Chronic Renal Failure in Patients With Cystic Fibrosis After Lung Transplantation (MUCO-IRC) [NA]
This terminated clinical trial investigated whether urinary PIIINP levels could predict development of chronic kidney disease in cystic fibr…
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability [NA]
This completed clinical trial evaluated ex-vivo perfusion and ventilation of donor lungs recovered from non-heart-beating donors to assess t…
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: (Study: Vertex IIS) Does Ivacaftor Alter Wild Type CFTR-Open Probability In The Sweat Gland Secretory Coil? [NA]
Clinical trial update for the Vertex IIS study investigating whether ivacaftor alters wild-type CFTR-open probability in the sweat gland sec…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: A Study of OligoG in Cystic Fibrosis Subjects With Burkholderia Spp. Infection [Phase 2]
A Phase 2 study evaluating OligoG in cystic fibrosis subjects with Burkholderia spp. infection has completed. The trial was sponsored by Alg…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: A Phase IIb Study of OligoG in Subjects With Cystic Fibrosis [Phase 2]
The document notes the Phase IIb trial of OligoG in subjects with cystic fibrosis has completed status (COMPLETED) according to ClinicalTria…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Behavioral & Nutritional Treatment to Help CF Preschoolers Grow [NA]
This completed ClinicalTrials.gov study evaluated a behavioral and nutritional program to support growth in preschool children with cystic f…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Evaluation of an Airway Clearance System [NA]
A completed clinical trial evaluated an airway clearance system for cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation [Phase 2]
Phase 2 study assessing VX-661 (tezacaftor) alone and in combination with ivacaftor in people with the F508del CFTR mutation; trial complete…
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion [Phase 2]
Phase 2 study evaluating safety and efficacy of VX-661 in combination with ivacaftor in cystic fibrosis patients homozygous for the F508del-…
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CLINICAL_TRIALS trial_result · 2018-04-12Clinical Trial Update: A Study to Evaluate Safety, PK and PD of FDL169 in Cystic Fibrosis Subjects [Phase 1]
A Phase 1 study evaluating safety, pharmacokinetics (PK) and pharmacodynamics (PD) of FDL169 in cystic fibrosis subjects has completed.