Cystic Fibrosis
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EMA label_change · 2025-02-28Combination of cystic fibrosis medicines to treat patients with rare mutations
EMA issued a positive opinion to extend the indication of cystic fibrosis modulator medicines so that all patients with modulator-responsive…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Evaluation of Lung T1-MRI in Pediatric Cystic Fibrosis Patients
This clinical trial evaluated Lung T1-MRI imaging in pediatric cystic fibrosis patients and has completed, potentially informing future use …
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Alternate Measures of Glucose During OGTT Testing for CFRD
This update notes the completion of a clinical trial investigating alternate glucose measures during OGTT testing for cystic fibrosis-relate…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Inhaled Therapy Adherence and Outcomes to Kaftrio in Cystic Fibrosis
This completed clinical trial assesses adherence to inhaled Kaftrio (elexacaftor/tezacaftor/ivacaftor) in cystic fibrosis and the associated…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Evaluation of New Device for Beta-adrenergic Sweat Test in the Context of Stratification of Patient With Cystic Fibrosis [NA]
A clinical trial update describes an ongoing study evaluating a new device for beta-adrenergic sweat testing to stratify patients with cysti…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Regional Phenotyping of CF and Non-CF Bronchiectasis
A ClinicalTrials.gov entry for a study on regional phenotyping of cystic fibrosis and non-CF bronchiectasis, sponsored by Cincinnati Childre…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Cystic Fibrosis in the Kidney: Monitoring the Effectiveness of Elexacaftor/tezacaftor/ivacaftor in Urine After a Short Pause of Therapy [NA]
A clinical trial update evaluating the effectiveness of elexacaftor/tezacaftor/ivacaftor in urine after a short pause of therapy, currently …
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Effects of Training Intensity on Physical Fitness and Body Composition in Cystic Fibrosis [NA]
A completed University of Kiel study evaluating how training intensity affects physical fitness and body composition in individuals with cys…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis
This clinical trial aims to study the pathogenicity of Achromobacter species in people with Cystic Fibrosis on Réunion Island; the study is …
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Ketone Supplementation in Cystic Fibrosis [NA]
A completed trial assessed ketone supplementation in cystic fibrosis patients, with the results posted on 2025-02-13.
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Tolerability of Hypertonic Saline in Infants With Cystic Fibrosis [Phase 1]
Phase 1 study evaluating tolerability of hypertonic saline in infants with cystic fibrosis. Results have been posted.
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: e-Health Program to Prevent Exacerbations in the Cystic Fibrosis Population [NA]
University of Valencia is conducting an e-Health program to prevent exacerbations in people with cystic fibrosis, and the study is currently…
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FDA approval · 2025-02-12FDA Approved: ACETYLCYSTEINE — Original Application (Somerset Therapeutics, LLC)
FDA approved the original application for acetylcysteine from Somerset Therapeutics, LLC, granting approval for a generic acetylcysteine pro…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Study to Assess Amphotericin B Cystetic for Inhalation (ABCI) Doses in Healthy Volunteers & People with Cystic Fibrosis [Phase 1]
Phase 1 clinical trial register update for Amphotericin B Cystetic for Inhalation (ABCI) to be tested in healthy volunteers and people with …
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Bacille Calmette-Guerin (BCG) Vaccine for Immune Protection Against Infections [Phase 2]
Phase 2 clinical trial update evaluating the Bacille Calmette-Guérin (BCG) vaccine for immune protection against infections in adults with c…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Effectiveness of the Hippotherapy Simulator in Children and Adolescents with Cystic Fibrosis [NA]
A completed clinical trial assessing the effectiveness of a Hippotherapy Simulator in children and adolescents with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: STeP IT UP CF: STimulating ImProved Health And Well-being In CysTic Fibrosis
The STeP IT UP CF trial in cystic fibrosis has completed, and its results have been posted.
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Steps Ahead: Optimising Physical Activity and Health in Adults With Cystic Fibrosis [NA]
A completed clinical trial sponsored by the University of Limerick investigating steps to optimize physical activity and health in adults wi…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: A Usability Validation of the MuCopilot Mobile Application, a Digital Tool for the Unsupervised Objective Assessment of Cystic Fibrosis [NA]
A usability validation study evaluating the MuCopilot mobile app for unsupervised objective assessment in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: A Prospective Study to Evaluate Biological and Clinical Effects of Significantly Corrected CFTR Function
The study evaluating biological and clinical effects of significantly corrected CFTR function in cystic fibrosis has completed. The update n…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF [NA]
This clinical trial update reports on a study investigating the mechanisms of vascular dysfunction and exercise tolerance in cystic fibrosis…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Functional Analysis by Dynamic Imaging of the Respiratory Epithelium in Infants With Cystic Fibrosis [NA]
This clinical trial evaluated functional analysis by dynamic imaging of the respiratory epithelium in infants with cystic fibrosis; the stud…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Intestinal Inflammation in CF Patients
Update on a clinical trial studying intestinal inflammation in cystic fibrosis patients; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Development a Core Set for Adults With Cystic Fibrosis Based on the ICF
This clinical trial update describes the completion of an effort to develop a core set of outcome measures for adults with cystic fibrosis b…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Progressive Muscle Relaxation in Pulmonary Rehab for Quality of Life, Mental Health, and Sleep in Cystic Fibrosis [NA]
Completed clinical trial evaluating progressive muscle relaxation as part of pulmonary rehabilitation. It aimed to improve quality of life, …