Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older [Phase 3]
Phase 3 clinical trial evaluating the long-term safety and efficacy of the triple CFTR modulator combination Vanzacaftor/Tezacaftor/Deutivac…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Diagnosis and Treatment of Patients With Cystic Fibrosis
This ClinicalTrials.gov update reports on a terminated trial investigating diagnostic and treatment approaches for patients with cystic fibr…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Personalized Theratyping Trial [EARLY_Phase 1]
An early-phase trial investigating personalized theratyping for cystic fibrosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Rare CFTR Mutation Cell Collection Protocol (RARE)
A clinical trial registry entry describing a protocol to collect cells for research on rare CFTR mutations in cystic fibrosis, with recruitm…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis [Phase 4]
Phase 4 trial investigating non-contrast lung perfusion mapping as a new imaging approach in cystic fibrosis.
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households: A Case-control Study of Exposure Risk at Home
This clinical trial update describes a case-control study in cystic fibrosis households to assess exposure risk to environmental reservoirs …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Impact of Elexacaftor-Tezacaftor-Ivacaftor Treatment on Metabolic, Epigenetic and Fecal Microbiota Profiles in People With Cystic Fibrosis.
A clinical trial assessing the effects of the trifecta CFTR modulator therapy elexacaftor/tezacaftor/ivacaftor on metabolic, epigenetic, and…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del [Phase 3]
Phase 3 long-term safety and efficacy study of elexacaftor/tezacaftor/ivacaftor in cystic fibrosis patients without the F508del mutation; th…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes [Phase 2, Phase 3]
This clinical trial update notes an ongoing Phase 2/3 study evaluating SGLT2 inhibitor therapy for cystic fibrosis-related diabetes, sponsor…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Pharmacokinetics of CFTR Modulators in Pregnant Individuals and in Postpartum Breastfeeding Mothers
A clinical trial update examining the pharmacokinetics of CFTR modulators in pregnant individuals and postpartum breastfeeding mothers, curr…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF [Phase 2]
A Phase 2 study evaluating the safety and tolerability of RCT2100, a CFTR mRNA therapy, in healthy participants and people with cystic fibro…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Study of the Prevalence of Active/Passive Smoking and Vaping Among Patients With Cystic Fibrosis
A clinical trial from University Hospital Strasbourg in France is recruiting to assess how common active, passive smoking and vaping are amo…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Regional Monitoring of CF Lung Disease [EARLY_Phase 1]
The trial NCT06339593 on regional monitoring of cystic fibrosis lung disease is in EARLY Phase 1 and currently recruiting.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Beta-cell Response to Incretin Hormones in Cystic Fibrosis [NA]
An ongoing University of Pennsylvania trial is exploring how incretin hormones affect beta-cell function in individuals with cystic fibrosis…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF) [NA]
A clinical trial is evaluating a skin-interfaced colorimetric bifluidic sweat sensor for diagnosing cystic fibrosis. The study is currently …
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 Trials [NA]
An ongoing clinical trial is evaluating individual patient responses to a drug for cystic fibrosis using N-of-1 trial designs and is current…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Hyperpolarized Imaging for New Treatments [Phase 4]
A Phase 4 clinical trial update in cystic fibrosis exploring hyperpolarized imaging to assess new treatments, currently active but not recru…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Pulmonary Vascular Disease in CF
Clinical trial update on pulmonary vascular disease in cystic fibrosis. Sponsored by Cincinnati Children's Hospital Medical Center, the stud…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Lung Transplant READY CF 2: A Multi-site RCT [NA]
An update on the Lung Transplant READY CF 2 multi-site randomized trial in cystic fibrosis; the study is currently active but not recruiting…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Study to Enable New Diagnostics for Pulmonary Microbes in People With CF
A clinical trial update describes a study aimed at enabling new diagnostics for pulmonary microbes in people with cystic fibrosis. The trial…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF)
This document reports a completed update on the natural history study of exocrine pancreatic function in infants with cystic fibrosis. The s…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection [Phase 1, Phase 2]
A double-blind, active-controlled Phase 1/2 study of aerosolized RSP-1502 in cystic fibrosis patients with chronic Pseudomonas aeruginosa lu…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants [Phase 1]
A Phase 1 dose-escalation study to evaluate the safety and pharmacokinetics of VX-581 in healthy participants, sponsored by Vertex Pharmaceu…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: The School-Age Children With Cystic Fibrosis and Their Parents on Health Literacy [NA]
This clinical trial update indicates ongoing recruitment for a study evaluating health literacy among school-age children with cystic fibros…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Nutrition Supplement for Cystic Fibrosis [NA]
Clinical trial entry for a nutrition supplement being studied in cystic fibrosis patients; the study status is not yet recruiting.