Cutaneous Melanoma
📧 Sign up to get email alerts when something new happens for Cutaneous Melanoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Krystal Biotech's KB707 is being studied in a Phase 1/2 trial for locally advanced or metastatic solid tumors, including cutaneous melanoma,…
-
CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Rituximab and Hyaluronidase Human in Patients With Advanced Melanoma Undergoing Nivolumab and Ipilimumab Therapy [Phase 2]
Phase 2 trial evaluating rituximab combined with hyaluronidase in patients with advanced cutaneous melanoma receiving nivolumab and ipilimum…
-
CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: TH1902 in Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for TH1902 in patients with advanced solid tumors. The study is currently active/not recruiting and …
-
CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Multicenter Phase 1b Trial Testing the Neoadjuvant Combination of Domatinostat, Nivolumab and Ipilimumab in IFN-gamma Signature-low and IFN-gamma Signature-high RECIST 1.1-measurable Stage III Cutaneous or Unknown Primary Melanoma [Phase 1, Phase 2]
A multicenter Phase 1b/2 neoadjuvant trial evaluating the combination of domatinostat, nivolumab, and ipilimumab in stage III cutaneous or u…
-
CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of TBio-4101 (TIL) with pembrolizumab in advanced solid tumors has been terminated; the trial includes multiple indications su…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: VX15/2503 With or Without Ipilimumab and/or Nivolumab in Patients With Resectable Stage IIIB-D Melanoma [Phase 1]
Phase 1 clinical trial evaluating VX15/2503 with or without ipilimumab and/or nivolumab in patients with resectable stage IIIB–D cutaneous m…
-
CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies [Phase 1, Phase 2]
This document reports a Phase 1/Phase 2 clinical trial evaluating GV20-0251 as monotherapy and in combination with pembrolizumab in several …
-
CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer [Phase 1]
Seagen's SEA-TGT (SGN-TGT) Phase 1 safety study in advanced cancers has been terminated. The study enrolled patients across multiple cancer …
-
CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating pembrolizumab with standard chemotherapy, tumor-infiltrating lymphocytes, and high- or low-dose aldesleukin in pati…
-
CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: The Study Aims to Measure the Metabolome in Melanoma Patients Using NMR Spectroscopy and Gas Chromatography and to Analyse Differences Depending on the Course of the Disease.
This clinical trial aims to measure the metabolome of melanoma patients using NMR spectroscopy and gas chromatography to analyze differences…
-
CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents [Phase 1, Phase 2]
Clinical trial update for OR502, a monoclonal antibody targeting LILRB2, studied alone and with anticancer agents in Phase 1/2; recruitment …
-
CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Ipilimumab and Nivolumab for the Treatment of Stage III-IV Unresectable Metastatic Melanoma [Phase 1]
A phase 1 trial evaluating the combination of ipilimumab and nivolumab for stage III/IV unresectable/metastatic cutaneous melanoma has been …
-
CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma [Phase 2]
This clinical trial update reports that the Phase 2 study of binimetinib plus nivolumab in BRAF V600 wildtype cutaneous melanoma has been te…
-
CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma [NA]
An ongoing clinical trial is comparing 1 cm versus 2 cm wide surgical excision margins for AJCC Stage II primary cutaneous melanoma and is c…
-
CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Versatile Ampification Single-Molecule Detection in Liquid Biopsy
A clinical trial update describes a study of versatile amplification single-molecule detection in liquid biopsy for melanoma. The trial is c…
-
CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I) [Phase 1]
HAMMER I is a Phase I trial evaluating hepatic ablation of melanoma liver metastases to enhance response to immunotherapy; the study status …
-
CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma [Phase 1, Phase 2]
Phase 1/2 study evaluating autologous genetically modified lymphocytes followed by Aldesleukin in patients with stage III or metastatic mela…
-
CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors [Phase 1]
Phase 1 study of LY3300054, an anti-PD-L1 antibody, given alone or in combination in adults with advanced refractory solid tumors, including…
-
CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Study of Ipilimumab, Nivolumab, and Cabozantinib in Patients With Cutaneous Melanoma [Phase 2]
Phase 2 trial of ipilimumab, nivolumab, and cabozantinib in refractory cutaneous melanoma was terminated. Results have been posted.
-
CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery [Phase 3]
A Phase 3 trial comparing high-dose recombinant interferon alfa-2B or ipilimumab to pembrolizumab in patients with surgically removed stage …
-
CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma [Phase 2]
A Phase 2 trial evaluating denosumab in combination with a PD-1 inhibitor in stage III/IV melanoma has completed with results posted.
-
CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: IFx-Hu2.0 Expanded Access Program
TuHURA Biosciences reports that the IFx-Hu2.0 Expanded Access Program is available for patients with cutaneous melanoma (Stage III/IV), Merk…
-
CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting
A completed clinical trial evaluated circulating tumor DNA (ctDNA) analysis as a tool for earlier detection of melanoma recurrence in high-r…
-
CLINICAL_TRIALS withdrawal · 2024-07-24Clinical Trial Update: Phase 1b/2 Study of the Combination of IMCgp100 With Durvalumab and/or Tremelimumab in Advanced Cutaneous Melanoma [Phase 1, Phase 2]
A Phase 1b/2 trial evaluating IMCgp100 in combination with durvalumab and/or tremelimumab for advanced cutaneous melanoma has been withdrawn…
-
CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial assessing ipilimumab with or without bevacizumab in patients with unresectable stage IIIC/IV cutaneous melanoma; results were …