Cutaneous Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Neoadjuvant and Adjuvant Checkpoint Blockade [Phase 2]
A Phase 2 neoadjuvant and adjuvant checkpoint blockade trial in melanoma completed with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating lifileucel with reduced-dose fludarabine/cyclophosphamide lymphodepletion and interleukin-2 for unresectable or met…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma [Phase 2]
Phase 2 trial evaluating the timing of pembrolizumab around surgery in high-risk melanoma, comparing post-operative administration to strate…
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers [Phase 1]
Phase 1 trial evaluating the combination of tacrolimus with immune checkpoint inhibitors nivolumab and ipilimumab in kidney transplant recip…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Endostar Plus Toripalimab as Adjuvant Therapy for Resectable Stage III-Oligometastatic Stage IV Cutaneous Melanoma [Phase 2]
A Phase 2 clinical trial evaluating Endostar in combination with toripalimab as adjuvant therapy for resectable stage III or oligometastatic…
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CLINICAL_TRIALS trial_result · 2023-05-01Clinical Trial Update: Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma [Phase 2]
A Phase 2 study compares the combination of ipilimumab and nivolumab versus ipilimumab alone in advanced melanoma, with results posted.
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CLINICAL_TRIALS trial_result · 2022-11-10Clinical Trial Update: Tumor-Infiltrating Lymphocytes After Combination Chemotherapy in Treating Patients With Metastatic Melanoma [Phase 2]
Phase 2 clinical trial evaluating tumor-infiltrating lymphocytes after combination chemotherapy in metastatic melanoma; results posted but n…
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: pDNA Intralesional Cancer Vaccine for Cutaneous Melanoma [EARLY_Phase 1]
Early-phase trial update for a pDNA intralesional cancer vaccine in cutaneous melanoma (Stage III/IV) with results posted.
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CLINICAL_TRIALS trial_result · 2022-06-22Clinical Trial Update: Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, Pembrolizumab, Nivolumab and Atezolizumab in Treating Patients With Advanced Melanoma, Lung, or Kidney Cancer [Phase 2]
Phase 2 trial investigating image-guided hypofractionated radiation therapy with nelfinavir mesylate and PD-1/PD-L1 inhibitors in advanced m…
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CLINICAL_TRIALS trial_result · 2022-04-19Clinical Trial Update: Safety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted Vaccine [Phase 1, Phase 2]
Phase 1/2 trial update reporting safety, tolerability, immunogenicity, and antitumor activity of GEN-009 adjuvanted vaccine in melanoma and …
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Immunization With 8 Peptides Mixed With CpG 7909 or Montanide ISA51 in Patients With Metastatic Cutaneous Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating immunization with 8 peptides plus CpG 7909 or Montanide ISA51 in metastatic cutaneous melanoma; study status term…
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma [Phase 3]
Phase 3 trial comparing PV-10 to chemotherapy or oncolytic viral therapy for locally advanced cutaneous melanoma was terminated with posted …
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CLINICAL_TRIALS trial_result · 2021-11-16Clinical Trial Update: A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma [Phase 2]
Phase 2 trial evaluating CDX-1401 vaccine with or without CDX-301 for various-stage melanoma has completed enrollment with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Prostaglandin Inhibition and Immune Checkpoint Blockade in Melanoma [Phase 2]
Phase 2 trial evaluating prostaglandin inhibition combined with immune checkpoint blockade in melanoma; completed with results posted in 202…
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CLINICAL_TRIALS trial_result · 2021-03-22Clinical Trial Update: Study Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive Melanoma [Phase 3]
A Phase 3 trial comparing MEK162 (binimetinib) to dacarbazine in NRAS-mutant unresectable or metastatic melanoma has completed; results were…
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer [Phase 1, Phase 2]
Phase 1/2 trial update of uprosertib combined with dabrafenib and trametinib in patients with stage IIIC-IV melanoma (cutaneous/metastatic/u…
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Capmatinib, Ceritinib, Regorafenib, or Entrectinib in Treating Patients With BRAF/NRAS Wild-Type Stage III-IV Melanoma [Phase 2]
Phase 2 clinical trial update evaluating multiple targeted therapies (capmatinib, ceritinib, regorafenib, or entrectinib) in patients with B…
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating nab-paclitaxel with bevacizumab or ipilimumab as first-line therapy in patients with unresectable stage IV melanoma…
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Confirmatory Trial in the Evaluation of Ca Electroporation for the Treatment of Cutaneous Metastases [NA]
A completed clinical trial evaluating calcium electroporation for treating cutaneous metastases in cutaneous melanoma; results posted.
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma [Phase 2]
NCI-sponsored Phase 2 trial evaluating ibrutinib in patients with refractory metastatic cutaneous melanoma; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating aldesleukin with or without ziv-aflibercept in patients with unresectable stage III-IV metastatic melanoma.
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CLINICAL_TRIALS research · 2018-07-19Clinical Trial Update: Quality of Life in Patients With Multimetastatic Melanoma Currently in Remission (QUALM)
This document describes a completed clinical trial update focusing on quality-of-life outcomes in patients with cutaneous melanoma that has …
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Evaluation of Oncoxin-Viusid® in Cutaneous Melanoma [Phase 2]
A Phase 2 clinical trial evaluating Oncoxin-Viusid for cutaneous melanoma has completed, with the study status reported as completed.
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CLINICAL_TRIALS trial_result · 2018-02-09Clinical Trial Update: Phase II Study of KW2871 Combined With High Dose Interferon-α2b in Patients With Metastatic Melanoma [Phase 2]
Phase II study investigating KW2871 with high-dose Interferon-α2b in metastatic/cutaneous melanoma completed with posted results in 2018.
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Epacadostat and Vaccine Therapy in Treating Patients With Stage III-IV Melanoma [Phase 2]
Phase 2 study evaluating epacadostat with a vaccine therapy in patients with stage III-IV melanoma has completed and posted results.