Cutaneous Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial evaluating defactinib and avutometinib, with or without encorafenib, in patients with brain metastases f…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study [Phase 1]
A Phase 1 study evaluating intra-lymphatic STI-3031 delivered with the Sofusa DoseConnect device for in-transit melanoma (clinical stage III…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors
This ClinicalTrials.gov entry describes a recruiting USC-led study evaluating social health, activity behaviors, and quality of life among y…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: The Impact of an Antibiotic (Cefazolin) Before Surgery on the Microbiome in Patients With Stage I-II Melanoma [Phase 1]
Phase 1 clinical trial evaluating whether preoperative Cefazolin affects the gut microbiome in patients with stage I–II cutaneous melanoma.
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients [Phase 3]
A Phase III randomized trial evaluating management of treatment-naive primary cutaneous melanoma in elderly patients is currently not recrui…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Time-of-Day Specified Immunotherapy for Advanced Melanoma, The TIME Trial [Phase 2]
Phase 2 trial evaluating time-of-day specified immunotherapy for advanced melanoma; currently recruiting.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma
An UCSF-led clinical trial is recruiting to characterize symptoms experienced by patients with cutaneous melanoma treated with immune checkp…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Quality of Life, Lifestyle, and Psychosocial Factors in Patients With Melanoma
This clinical trial is evaluating quality of life, lifestyle factors, and psychosocial aspects in patients with cutaneous melanoma and is cu…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases [Phase 1]
Phase 1 trial evaluating hepatic arterial infusion of autologous tumor-infiltrating lymphocytes in patients with metastatic melanoma to the …
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Locoregional or Systemic Administration of Autologous Tumor Infiltrating Lymphocytes in Patients With Metastatic Melanoma [Phase 1]
A Phase 1 clinical trial is evaluating locoregional or systemic administration of autologous tumor-infiltrating lymphocytes in patients with…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases [Phase 2]
Phase 2 study compares encorafenib + binimetinib + nivolumab versus ipilimumab + nivolumab in BRAF-V600 mutation melanoma with brain metasta…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: A Feasibility Study to Identify T-cell Responses to Neo-epitopes in Tumor Invaded Lymph Nodes (NeoEpitope) [NA]
Feasibility study by Institut Curie to identify T-cell responses to neo-epitopes in tumor-invaded lymph nodes, conducted for breast cancer a…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Guardant Health's ORACLE trial is currently recruiting to evaluate residual cancer using a liquid biopsy across multiple cancer types.
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Efficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint Blockade [Phase 2]
Phase 2 clinical trial evaluating anti-PD-1/PD-L1 antibodies in combination with bevacizumab and metronomic cyclophosphamide in patients wit…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Bone Loss in Melanoma Survivors Receiving Immunotherapy
A terminated clinical trial from MD Anderson Cancer Center studied bone loss in melanoma survivors treated with immunotherapy, including pat…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: 7T MRI Scan for the Early Detection of Melanoma Brain Metastases [NA]
A terminated clinical trial evaluating 7T MRI for the early detection of brain metastases in patients with stage IV cutaneous melanoma.
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors [Phase 1]
Phase 1, first-in-human dose-finding and expansion study of XmAb808 in combination with pembrolizumab in advanced solid tumors; the trial ha…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of APG-115 alone or with pembrolizumab in metastatic melanoma and other advanced solid tumors; the trial is currently active…
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CLINICAL_TRIALS withdrawal · 2025-08-07Clinical Trial Update: Aerosolized Sargramostim Added to Immunotherapy for the Treatment of Patients With Metastatic Melanoma to the Lung [Phase 1]
A Phase 1 trial evaluating aerosolized sargramostim in combination with immunotherapy for metastatic cutaneous melanoma with lung involvemen…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers [NA]
A multi-cancer prospective study evaluating double-positive circulating cells (CD45+ tumor marker) in several types of metastatic cancers; r…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Tebentafusp in Molecular Relapsed Disease (MRD) Melanoma [Phase 2]
Phase 2 clinical trial update for tebentafusp in molecularly relapsed melanoma shows an active but not recruiting study targeting both cutan…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: A Study of Neoadjuvant Therapy With BCD-217 (Nurulimab + Prolgolimab) in Patients With Resectable Stage III Skin Melanoma [Phase 3]
Clinical trial update on a Phase 3 neoadjuvant study of BCD-217 (Nurulimab + Prolgolimab) in patients with resectable Stage III skin melanom…
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CLINICAL_TRIALS other · 2025-07-02Clinical Trial Update: Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery [Phase 1, Phase 2]
A Phase 1/2 clinical trial of propranolol hydrochloride in combination with pembrolizumab for unresectable stage IIIC-IV cutaneous melanoma …
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6 [Phase 2]
The ARTISTRY-6 Phase 2 trial evaluating nemvaleukin alfa as monotherapy and in combination with pembrolizumab in patients with advanced cuta…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement [Phase 2]
A Phase 2 trial testing the combination of encorafenib and binimetinib before surgery for melanoma with lymph node involvement has been term…