Cutaneous Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases [Phase 1]
Phase 1 trial evaluating stereotactic radiosurgery, NovoTTF-200M, and immune checkpoint inhibitors for melanoma brain metastases was termina…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Aerosolized Aldesleukin in Treating Patients With Lung Metastases [Phase 1]
Phase 1 study evaluating aerosolized aldesleukin (interleukin-2) in patients with cancers that have metastasized to the lung, including mela…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors [Phase 1]
This clinical trial update describes a Phase 1 study of PF-08046049/SGN-BB228 in advanced melanoma and other solid tumors, with the conditio…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors [Phase 1]
Novartis' Phase 1 dose-finding trial of TNO155 in adults with advanced solid tumors has been terminated. No efficacy results are provided in…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma [Phase 2, Phase 3]
This clinical trial update describes a Phase II/III study of the combination nivolumab, ipilimumab, and GM-CSF in patients with advanced cut…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma [NA]
The clinical trial evaluating MoleMapper, Visiomed, and confocal microscopy for melanoma screening has been terminated.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma [Phase 1]
Phase 1 trial update reports proof of concept for TBio-4101 in combination with lymphodepleting chemotherapy and IL-2 for relapsed/refractor…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases [Phase 1, Phase 2]
A Phase 1/2 trial evaluating Bintrafusp alfa in combination with Pimasertib for brain metastases has been terminated, with results posted in…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA, IIB, or IIIA Melanoma [Phase 2]
A Phase 2 trial is evaluating atorvastatin to prevent metastasis in patients with resected high-risk cutaneous melanoma (stages IIA, IIB, II…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases [Phase 1]
This phase 1 study assessed pembrolizumab in combination with stereotactic radiosurgery for patients with brain metastases from melanoma or …
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma [Phase 3]
Phase 3 clinical trial evaluating two sequencing strategies for BRAFV600-mutant stage III–IV melanoma: dabrafenib plus trametinib followed b…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Dabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 Mutation [Phase 2]
A Phase 2 clinical trial evaluating dabrafenib plus trametinib given before and after surgery in patients with stage IIIB-C cutaneous melano…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma [Phase 1]
Phase 1 trial of the modified virus VSV-IFNbetaTYRP1 in stage III-IV melanoma was terminated.
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers [Phase 1]
Phase 1 study assessing safety and early efficacy of KFA115 alone and in combination with pembrolizumab in select advanced cancers; the tria…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Enhancing Skin Cancer Early Detection and Treatment in Primary Care [NA]
A completed clinical trial focused on improving early detection and treatment of cutaneous melanoma in primary care settings. The study resu…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study [Phase 1]
A Phase 1 study evaluating intra-lymphatic STI-3031 delivered with the Sofusa DoseConnect device for in-transit melanoma (clinical stage III…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: A Feasibility Study to Identify T-cell Responses to Neo-epitopes in Tumor Invaded Lymph Nodes (NeoEpitope) [NA]
Feasibility study by Institut Curie to identify T-cell responses to neo-epitopes in tumor-invaded lymph nodes, conducted for breast cancer a…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Bone Loss in Melanoma Survivors Receiving Immunotherapy
A terminated clinical trial from MD Anderson Cancer Center studied bone loss in melanoma survivors treated with immunotherapy, including pat…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: 7T MRI Scan for the Early Detection of Melanoma Brain Metastases [NA]
A terminated clinical trial evaluating 7T MRI for the early detection of brain metastases in patients with stage IV cutaneous melanoma.
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors [Phase 1]
Phase 1, first-in-human dose-finding and expansion study of XmAb808 in combination with pembrolizumab in advanced solid tumors; the trial ha…
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6 [Phase 2]
The ARTISTRY-6 Phase 2 trial evaluating nemvaleukin alfa as monotherapy and in combination with pembrolizumab in patients with advanced cuta…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement [Phase 2]
A Phase 2 trial testing the combination of encorafenib and binimetinib before surgery for melanoma with lymph node involvement has been term…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Rituximab and Hyaluronidase Human in Patients With Advanced Melanoma Undergoing Nivolumab and Ipilimumab Therapy [Phase 2]
Phase 2 trial evaluating rituximab combined with hyaluronidase in patients with advanced cutaneous melanoma receiving nivolumab and ipilimum…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Multicenter Phase 1b Trial Testing the Neoadjuvant Combination of Domatinostat, Nivolumab and Ipilimumab in IFN-gamma Signature-low and IFN-gamma Signature-high RECIST 1.1-measurable Stage III Cutaneous or Unknown Primary Melanoma [Phase 1, Phase 2]
A multicenter Phase 1b/2 neoadjuvant trial evaluating the combination of domatinostat, nivolumab, and ipilimumab in stage III cutaneous or u…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of TBio-4101 (TIL) with pembrolizumab in advanced solid tumors has been terminated; the trial includes multiple indications su…