Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases [Phase 1]
A Phase 1 trial evaluating preoperative yttrium-90 radioembolization to control colorectal liver metastases and promote future liver remnant…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Precision-MRD: Prospective Observational Study of Biomarker-directed Systemic Therapy for Colorectal Cancer Patients With Minimal Residual Disease
This clinical trials registry entry describes a prospective observational study evaluating biomarker-directed systemic therapy for colorecta…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Epigenetic Signature for CRC Early Detection
This clinical trial update describes an ongoing study evaluating an epigenetic signature based on DNA methylation in cell-free DNA for early…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread [Phase 2]
This update reports Phase 2 results from a trial of nivolumab alone or in combination therapy for metastatic colorectal cancer, with results…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Use of ctDNA for Monitoring of Stage III Colorectal Cancer
This clinical trial update reports on using circulating tumor DNA to monitor disease status in Stage III colorectal cancer; the study is cur…
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EMA approval · 2025-11-05EMA Authorised: Braftovi (Encorafenib) — Pierre Fabre Medicament
The EMA authorised Braftovi (encorafenib) for melanoma and colorectal cancer. Pierre Fabre Medicament is the marketing authorization holder.
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: cfDNA 5mC/5hmC Biomarkers to Predict Chemotherapy Response in Metastatic Colorectal Cancer
A clinical trial is evaluating cfDNA 5mC/5hmC biomarkers to predict chemotherapy response in metastatic colorectal cancer and is currently r…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Development of a cfDNA 5mC/5hmC-based Biomarker Panel to Predict Targeted Therapy Efficacy in mCRC
A clinical trial is evaluating a cfDNA 5mC/5hmC-based biomarker panel to predict targeted therapy efficacy in metastatic colorectal cancer a…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery [Phase 1, Phase 2]
Ongoing Phase 1/2 trial assessing whether a standardized preoperative diet that modulates the gut microbiome can reduce recurrence and metas…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: ColoSeal™ ICD System Safety and Feasibility Study [NA]
This clinical trial update indicates that the ColoSeal ICD System safety and feasibility study for colorectal cancer is currently recruiting…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Head to Head Pilot Trial of Mailed Cologuard to Mailed FIT [NA]
A head-to-head pilot trial comparing mailed Cologuard to mailed FIT for colorectal cancer screening; the study is currently active but not r…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers [Phase 1, Phase 2]
A Phase 1/2 trial update for Vorbipiprant (CR6086) combined with Balstilimab (AGEN2034) in stage IV refractory pMMR-MSS colorectal cancer an…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors [Phase 2]
A Phase 2 trial evaluating niraparib in patients with advanced PALB2-mutated tumors was terminated; results have been posted for multiple so…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab [Phase 1]
A Phase 1 clinical trial update shows ABBV-400 alone or with bevacizumab being studied in adults with advanced solid tumors, including non-s…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Abnormal Food Timing and Circadian Dyssynchrony in Alcohol Induced Colon Carcinogenesis [NA]
A clinical trial update describing a study of abnormal food timing and circadian dyssynchrony in alcohol-induced colon carcinogenesis. The t…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Colorectal Cancer Screening in the Homeless [NA]
George Washington University is conducting a clinical trial to evaluate colorectal cancer screening among homeless individuals. The study st…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: Immune Mechanisms After Radiofrequency Ablation of Pulmonary Metastases From Colorectal Cancer Origin [NA]
A clinical trial update examining immune mechanisms after radiofrequency ablation of pulmonary metastases originating from colorectal cancer…
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CLINICAL_TRIALS other · 2025-10-23Clinical Trial Update: Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer [Phase 3]
A Phase 3 clinical trial comparing XL092 plus atezolizumab versus regorafenib in metastatic colorectal cancer is currently active but not re…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Patient Navigation for Colorectal Cancer Screening [NA]
A clinical trial update about a study on patient navigation to improve colorectal cancer screening uptake, currently enrolling by invitation…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Rural Colon Cancer Screening Toolkit Intervention [NA]
A clinical trial evaluating a rural colon cancer screening toolkit intervention has completed. The study tracked colon cancer screening effo…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy [EARLY_Phase 1]
A Phase 1 trial is evaluating cannabidiol (CBD) for neuroprotection against oxaliplatin-induced peripheral neuropathy in cancer patients and…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
The ALLUME Study is evaluating microwave ablation versus wedge resection for treatment of lung, sarcoma, and colorectal lesions, including v…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Transanal Irrigation for the Management of Early Low Anterior Resection Syndrome (LARS) [NA]
This entry describes a clinical trial evaluating transanal irrigation for the management of early Low Anterior Resection Syndrome in patient…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE) [Phase 2, Phase 3]
A Phase 2/3 trial evaluating the diagnostic performance of GEH300079 (68Ga) PET/CT for detecting pancreatic cancer in patients with colorect…
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CLINICAL_TRIALS withdrawal · 2025-10-21Clinical Trial Update: Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial combining AlloStim with an anti-PD-L1 agent for fourth-line metastatic microsatellite-stable colorectal cancer has been with…