Clinical Trial Update: Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors [Phase 2]

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Summary

A Phase 2 trial evaluating niraparib in patients with advanced PALB2-mutated tumors was terminated; results have been posted for multiple solid tumor indication…

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Diseases / indications

• Breast Cancer
• Colorectal Cancer
• Endometrial Cancer
• Esophageal Cancer
• Head and Neck Cancer
• Lung Cancer
• Melanoma
• Pancreatic Cancer

Drugs mentioned

• Niraparib (Niraparib)

Snippet

Sponsor: Tempus AI | Conditions: Solid Tumor, Breast Tumor | Phase 2 | Status: TERMINATED | Results posted: 2025-10-29