Colorectal Cancer
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients [NA]
A Memorial Sloan Kettering Cancer Center study to develop educational materials about genetic testing for a diverse group of cancer patients…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer. [Phase 1, Phase 2]
An open-label Phase 1/2 study evaluating the efficacy and safety of Etrumadenant-based treatment combinations in metastatic colorectal cance…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Immunotherapy for Third Line Metastatic Colorectal Cancer [Phase 2]
The Phase 2 trial evaluating immunotherapy for third-line metastatic colorectal cancer has completed. The snippet does not include efficacy …
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory [Phase 2]
A Phase 2 clinical trial is evaluating hydroxychloroquine in combination with encorafenib and either cetuximab or panitumumab for metastatic…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describing safety, tolerability, and imaging with [68Ga]Ga-DPI-4452 and safety, tolerability, and efficacy…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/2 study of the monoclonal antibody IMT-009 in various advanced solid tumors and lymphomas, with t…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
This document provides a clinical trial update for the SurvOlderAdults Study, which investigates surveillance colonoscopy in older adults at…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Vaginal Dilator Therapy After Pelvic Radiation [NA]
Duke University is conducting a trial to evaluate vaginal dilator therapy after pelvic radiation. The study is not yet recruiting and target…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Dose-dense Capecitabine Schedule [7days on _7 Days Off] in Colorectal Cancer in Comparison With Standered Regimen [Phase 2]
Phase 2 clinical trial update evaluating a dose-dense capecitabine schedule (7 days on, 7 days off) in colorectal cancer, compared with the …
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial from Akeso is evaluating AK112 with or without AK117 in metastatic colorectal cancer; the study status is active but not rec…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: YASU Research Registry: For Young Adults With Cancer
Clinical trial update indicating termination of the YASU Research Registry for young adults with cancer, listing several cancer conditions i…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers [Phase 1]
A Phase 1 study of AMG 199 in MUC17-positive solid tumors including gastric, gastroesophageal junction, colorectal, and pancreatic cancers h…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia [NA]
A completed clinical trial sponsored by the University of Kentucky evaluating implementation science approaches to accelerate colorectal can…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: A Study of the Possible Effects of Medication on Young Onset Colorectal Cancer (YOCRC)
A clinical trial at Memorial Sloan Kettering Cancer Center is investigating the possible effects of a medication on young-onset colorectal c…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: First in Human Study of TORL-3-600 in Participants With Advanced Cancer [Phase 1]
First-in-human Phase 1 study of TORL-3-600 in participants with advanced cancer, including colorectal cancer; the trial is currently active …
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Study of Hepatic Arterial Infusion With Intravenous Irinotecan, 5FU and Leucovorin With or Without Panitumumab, in Patients With Wild Type RAS Who Have Resected Hepatic Metastases From Colorectal Cancer [Phase 2]
A Phase 2 trial evaluating hepatic arterial infusion with intravenous irinotecan, 5-fluorouracil and leucovorin, with or without panitumumab…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of BMS-813160 in combination with chemotherapy or nivolumab for advanced solid tumors has completed and results have been po…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: PR-CEAL: Community Outreach Engagement Group [NA]
This document reports a completed clinical trial update for the PR-CEAL Community Outreach Engagement Group, focusing on breast, colorectal,…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial [Phase 4]
A Phase 4 COOP SIT trial is investigating cleansing options in outpatient settings to improve tolerance for colonoscopy. Recruitment is ongo…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
This clinical trial update describes a study evaluating detection of tumor cells and tumor DNA in blood, urine, and bone marrow across multi…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Tislelizumab in People With Colorectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating tislelizumab for colorectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Delayed Systemic Therapy Following Destructive Local Treatment of Pulmonary Oligometastases After No Evidence of Disease (NED) in Colorectal Cancer. [Phase 2]
Phase 2 clinical trial evaluating delaying systemic therapy after destructive local treatment of pulmonary metastases in colorectal cancer p…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Clinical Efficacy of Transarterial Chemoembolization in Elderly Patients With Advanced Unresectable Colorectal Cancer [Phase 2]
A Phase 2 clinical trial update on transarterial chemoembolization for elderly patients with advanced unresectable colorectal cancer. The st…
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Prognostic Value of Circulating Tumoral Free DNA Versus Circulating Tumoral Cells in Patients With Colorectal Cancer Stage II-III [NA]
A completed clinical trial evaluating whether circulating tumor DNA or circulating tumor cells provides prognostic information for patients …
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy [NA]
Completed clinical trial evaluating a novel dose adjustment algorithm to prevent cytopenia-related delays during FOLFOX chemotherapy; result…