Clear Cell Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: [18F]PT2385 PET/CT in Patients With Renal Cell Carcinoma [Phase 1]
Phase 1 clinical trial evaluating [18F]PT2385 PET/CT in renal cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors [Phase 2]
This Phase 2 clinical trial update reports recruitment for an alternative cabozantinib dosing schedule in metastatic renal cell carcinoma an…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: A Clinical Trial of Envafolimab Combined With Lenvatinib for Kidney Cancer With Liver Spread [Phase 2]
A Phase 2 clinical trial update indicates a study of Envafolimab in combination with Lenvatinib for clear cell renal cell carcinoma with liv…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension Study [Phase 3]
Phase 3 China-extension study comparing pembrolizumab-based regimens (with belzutifan and lenvatinib, or with quavonlimab and lenvatinib) ve…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Ivonescimab Prior to Surgery for the Treatment of High-Risk Localized Clear Cell Renal Cell Cancer [Phase 2]
A Phase 2 clinical trial to evaluate Ivonescimab before surgery for high-risk localized clear cell renal cell carcinoma is not yet recruitin…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy [Phase 2]
A Phase 2 clinical trial update evaluating RP2 in combination with tivozanib for metastatic renal cell carcinoma after progression on immuno…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describing safety, tolerability, and imaging with [68Ga]Ga-DPI-4452 and safety, tolerability, and efficacy…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma [Phase 1]
An ongoing Phase I study at MD Anderson tests allogeneic CD70 CAR NK cells engineered with TGF-beta receptor type 2 knockout for treatment-r…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Prior Axitinib as a Determinant of Outcome of Renal Surgery [Phase 2]
Phase 2 clinical trial evaluating whether prior axitinib affects surgical outcomes in clear cell renal cell carcinoma; the study is currentl…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Neoadjuvant Study With Combination Immuno-oncology for Primary Clear Cell Renal Cell Cancer [Phase 2]
Phase 2 neoadjuvant immuno-oncology trial for primary clear cell renal cell carcinoma. The study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Modulation of the Bone Immune Microenvironment Following Cabozantinib Treatment of Bone Metastatic Clear Cell Renal Cell Carcinoma: Proof of Concept Study [Phase 1]
Phase 1 clinical trial update evaluating cabozantinib's effects on the bone immune microenvironment in bone-metastatic clear cell renal cell…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After Surgery [Phase 2]
Phase 2 trial exploring adding CBM588 to pembrolizumab for renal cell carcinoma after surgery; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit [Phase 1]
Phase 1 study evaluating NN3201, a c-Kit targeted antibody-drug conjugate, in advanced and/or metastatic solid tumors expressing c-Kit; curr…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: AB-2100, an Integrated Circuit T Cell Therapy in Patients With Recurrent Clear-cell Renal Cell Carcinoma (ccRCC) [Phase 1, Phase 2]
Arsenal Biosciences reports an ongoing Phase 1/2 clinical trial of AB-2100, an integrated circuit T cell therapy, in patients with recurrent…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL Trial [Phase 2]
Phase 2 BELIEVE-VHL trial is assessing real-world effectiveness and pharmacogenetics of belzutifan in Von Hippel-Lindau syndrome; recruitmen…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial [Phase 3]
The PROBE trial is a Phase 3 study evaluating immunotherapy-based combination therapy for metastatic renal cell carcinoma with or without su…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial [Phase 1, Phase 2]
Clinical trial update describing the ICON study, evaluating a combination of an inulin gel with ipilimumab and nivolumab for locally advance…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Multiomics Approach in Metastatic Clear Renal Cell Carcnoma
This clinical trial update describes a study using a multiomics approach for metastatic clear cell renal cell carcinoma, with the trial curr…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: KSD-201 Treatment for Advanced Clear Cell Renal Cell Carcinoma: an Early Exploratory Clinical Study [EARLY_Phase 1]
An early exploratory Phase 1 study evaluating KSD-201 for advanced clear cell renal cell carcinoma; currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Study of HS-10516 Combination Therapy in Patients With Advanced Renal Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating HS-10516 combination therapy in patients with advanced renal cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Clinical Evaluation of [68Ga]Ga-XT771 PET for Diagnosis in Patients With Glioblastoma and Clear Cell Renal Cell Carcinoma [EARLY_Phase 1]
Early-phase clinical trial evaluating the diagnostic PET tracer [68Ga]Ga-XT771 for glioblastoma and clear cell renal cell carcinoma, current…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: 89Zr-DFO-girentuximab Expanded Access Program (EAP)
This clinical trial update indicates that the 89Zr-DFO-girentuximab Expanded Access Program for Clear Cell Renal Cell Carcinoma is available…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders [Phase 2]
A Phase 2 clinical trial at Oslo University Hospital is testing fecal microbiota transplantation from clinical responders in cancer patients…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases [Phase 2]
A Phase 2 clinical trial update describes Zanzalintinib for metastatic clear cell renal cell carcinoma with bone metastases, currently not y…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Belzutifan's Role in Active Surveillance Versus Treatment for Indolentmetastatic Clear Cell Renal Ccell Carcinoma (BRAVE-RCC) [Phase 2]
A Phase 2 trial evaluating belzutifan for indolent metastatic clear cell renal cell carcinoma, comparing active surveillance with treatment;…