Rhinosinusitis with Nasal Polyps
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) and Comorbid Asthma [Phase 1, Phase 2]
Clinical trial update for the drug candidate BBT002 in healthy volunteers and in patients with chronic rhinosinusitis with nasal polyps and …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of CM326 in Participants With Chronic Rhinosinusitis With Nasal Polyposis [Phase 3]
A Phase III randomized, double-blind, placebo-controlled trial evaluating CM326 for chronic rhinosinusitis with nasal polyps; the study is c…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Mechanisms of Smell Improvement With Dupilumab. [Phase 4]
Phase 4 clinical trial update on the mechanisms by which dupilumab may improve sense of smell in chronic rhinosinusitis with nasal polyps.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of LP-003 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) [Phase 2]
This clinical trial update describes a Phase 2 study evaluating the efficacy and safety of LP-003 Injection for chronic rhinosinusitis with …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
A phase 2 proof-of-concept trial evaluating Lunsekimig versus placebo in adults with chronic rhinosinusitis with nasal polyps; the study is …
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis [Phase 3]
Phase 3 trial update reporting efficacy and safety results for tezepelumab in adults with severe chronic rhinosinusitis with nasal polyps; r…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Th Study Wants to Compare the Best Technique for Sinus Operation in CRSWNP [NA]
A clinical trial sponsored by Kafrelsheikh University aims to compare sinus surgery techniques for chronic rhinosinusitis with nasal polyps …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis
Ongoing clinical trial evaluating dupilumab in ethnically diverse patients with chronic rhinosinusitis with nasal polyps; the study is curre…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: The Role of IL5 in Epithelial Cell Integrity [EARLY_Phase 1]
An early-phase Phase 1 trial sponsored by Johns Hopkins University examines the role of IL-5 in epithelial cell integrity in chronic rhinosi…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Efficacy of Long-Term Low Dose Macrolide Therapy in Preventing Early Recurrence of Nasal Polyps After Endoscopic Sinus Surgery [NA]
A completed clinical trial assessing whether long-term low-dose macrolide therapy reduces early recurrence of nasal polyps after endoscopic …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Real-Time Diagnosis of Eosinophilic Nasal Polyps Using High-Sensitivity Spectroscopy [NA]
This clinical trial update describes a study evaluating real-time diagnosis of eosinophilic nasal polyps in chronic rhinosinusitis with nasa…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps [NA]
This clinical trial update shows ongoing recruitment for a study evaluating in-clinic endoscopic polypectomy to treat chronic rhinosinusitis…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Study in Adults With Severe Chronic Rhinosinusitis With Nasal Polyposis Treated With Dupilumab in France
The update reports an ongoing France-based study evaluating dupilumab in adults with severe chronic rhinosinusitis with nasal polyps, with t…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis [NA]
ClinicalTrials.gov entry for a study of paclitaxel-coated balloon treatment in chronic rhinosinusitis with and without nasal polyps; the tri…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Clinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal Polyps [Phase 3]
A Phase 3 clinical trial update for TQC2731 Injection in chronic rhinosinusitis with nasal polyps (CRSwNP), currently recruiting.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Evaluation of the Safety and Performance of a Bioresorbable Nasal Dressing Containing Mometasone Furoate (MF) [NA]
Clinical trial update on a bioresorbable nasal dressing containing mometasone furoate for chronic rhinosinusitis (with or without nasal poly…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
Phase 3 results evaluate the efficacy and safety of Depemokimab (GSK3511294) in adults with chronic rhinosinusitis with nasal polyps. The st…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 clinical trial evaluating 611 for chronic rhinosinusitis with nasal polyps is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP
A completed clinical trial from Brigham and Women's Hospital studied IL-5R signaling in non-eosinophil upper airway cells in chronic rhinosi…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Regulatory Post-Marketing Surveillance of Xolair® for Chronic Rhinosinusitis With Nasal Polyps
This document reports the completed regulatory post-marketing surveillance study of Xolair (omalizumab) for chronic rhinosinusitis with nasa…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: A Extension Clinical Study of TQC2731 Injection in the Treatment of Chronic Sinusitis With Nasal Polyps [Phase 2]
This update reports the completion of an extension Phase 2 clinical trial evaluating TQC2731 injection for chronic rhinosinusitis with nasal…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Efficacy and Safety of SHR-1905 Injection in Subjects With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
Phase 3 clinical trial update for SHR-1905 injections in chronic rhinosinusitis with nasal polyps; the study is currently recruiting to asse…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients [Phase 4]
Phase 4 trial comparing dupilumab versus omalizumab in Type 2 inflammatory disease patients (chronic rhinosinusitis with nasal polyps and as…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Anti-IL-5 Therapy With Simple Polypectomy Versus Extended Endoscopic Sinus Surgery for CRSwNP [Phase 4]
A Phase 4 clinical trial comparing anti-IL-5 therapy with simple polypectomy versus extended endoscopic sinus surgery for chronic rhinosinus…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Dupilumab in Chinese Adult Participants With CRSwNP [Phase 3]
Phase 3 trial evaluating dupilumab in Chinese adults with chronic rhinosinusitis with nasal polyps has completed and results were posted.