Granulomatous Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-11-30Clinical Trial Update: Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD) [Phase 2]
Phase 2 trial update on the pharmacokinetics of posaconazole in children with Chronic Granulomatous Disease.
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CLINICAL_TRIALS trial_result · 2020-05-01Clinical Trial Update: Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant Cyclophosphamide [Phase 1, Phase 2]
Phase 1/2 trial update on haploidentical transplant with post-transplant cyclophosphamide for Chronic Granulomatous Disease (CGD); study ter…
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients [Phase 2]
Phase 2 clinical trial evaluating Plerixafor with G-CSF as conditioning agents before hematopoietic stem cell transplantation in patients wi…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Effect of IFN-γ on Innate Immune Cells [Phase 1]
Phase 1 trial investigating the effect of interferon-gamma on innate immune cells in chronic granulomatous disease has completed.
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CLINICAL_TRIALS trial_result · 2018-11-09Clinical Trial Update: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease [Phase 2]
Phase 2 clinical trial update on matched donor transplantation for Chronic Granulomatous Disease with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Gene Therapy for Chronic Granulomatous Disease [EARLY_Phase 1]
An early-phase gene therapy trial for Chronic Granulomatous Disease sponsored by NIAID was terminated.
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) [Phase 2]
Phase 2 trial update for reduced intensity conditioning in hemophagocytic syndromes and selected primary immune deficiencies completed with …
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous Disease
This clinical trial update describes the transition from pediatric to adult care for adolescents with chronic granulomatous disease and indi…
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease [Phase 4]
Phase 4 trial update on biochemical response to interferon-gamma in subjects with a CGD gene mutation; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up [Phase 1]
Long-term follow-up data from an early-phase gene therapy trial for Chronic Granulomatous Disease are reported. The document updates on safe…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Use of Busulfan as Conditioning Agent for a Second Stem Cell Transplant [Phase 1]
This update summarizes a Phase 1 trial evaluating busulfan as a conditioning agent for a second stem cell transplant in patients with chroni…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Posaconazole to Treat Invasive Fungal Infections [Phase 3]
Phase 3 trial of posaconazole for invasive fungal infections has completed, involving patients with chronic granulomatous disease and Hyper-…
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CLINICAL_TRIALS trial_result · 2016-06-17Clinical Trial Update: Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells [Phase 2]
Phase 2 study evaluating related hematopoietic stem cell transplantation for several genetic blood disorders; the trial was terminated and r…
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CLINICAL_TRIALS trial_result · 2015-12-29Clinical Trial Update: Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease [Phase 1, Phase 2]
Infliximab was studied in a Phase 1/2 trial for Crohn's-like inflammatory bowel disease in patients with chronic granulomatous disease. The …
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FDA approval · 2015-08-27FDA Approved: ACTIMMUNE — Supplemental Application (Horizon Therapeutics USA, Inc.)
FDA approved a supplemental application for ACTIMMUNE (interferon gamma-1b) submitted by Horizon Therapeutics USA, Inc.
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation [NA]
Clinical trial update indicating termination of an Alefacept plus allogeneic hematopoietic stem cell transplantation study, with results pos…
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CLINICAL_TRIALS trial_result · 2014-12-09Clinical Trial Update: Study of Total Body Irradiation and Fludarabine Followed By Allogeneic Peripheral Blood Stem Cell or Bone Marrow Transplantation in Combination With Cyclosporine and Mycophenolate Mofetil in Patients With Inherited Disorders [NA]
A completed clinical trial evaluating total body irradiation and fludarabine followed by allogeneic transplantation with cyclosporine and my…
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CLINICAL_TRIALS research · 2014-09-05Clinical Trial Update: Chronic Granulomatous Disease Study in China
Clinical trial update for Chronic granulomatous disease in China, sponsored by Shanghai Children's Medical Center; current trial status is u…
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CLINICAL_TRIALS trial_result · 2013-11-19Clinical Trial Update: Targeted Busulfan, Fludarabine Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Chronic Granulomatous Disease(CGD) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a targeted busulfan and fludarabine conditioning regimen for hematopoietic stem cell transplantation i…
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CLINICAL_TRIALS withdrawal · 2012-06-04Clinical Trial Update: Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD) [Phase 1, Phase 2]
A Phase 1/2 trial of lentiviral gene therapy for X-linked chronic granulomatous disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2011-09-27Clinical Trial Update: Gene Therapy for X-linked Chronic Granulomatous Disease (CGD) in Children [Phase 1, Phase 2]
Phase 1/2 gene therapy trial for X-linked Chronic Granulomatous Disease in children has completed, sponsored by the University of Zurich. Th…
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CLINICAL_TRIALS trial_result · 2009-10-15Clinical Trial Update: Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies [NA]
This clinical trial update notes termination of an allogeneic bone marrow transplantation study for patients with primary immunodeficiencies…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Modified Stem Cell Transplantation Procedure for Treating Chronic Granulomatous Disease [Phase 2]
Phase 2 clinical trial evaluating a modified stem cell transplantation procedure for chronic granulomatous disease has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Treatment of Chronic Granulomatous Disease With Allogeneic Stem Cell Transplantation Versus Standard of Care [Phase 3]
A Phase 3 trial comparing allogeneic stem cell transplantation to standard of care in chronic granulomatous disease has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Itraconazole for the Prevention of Fungal Infections in Chronic Granulomatous Disease [Phase 2]
Phase 2 trial evaluating itraconazole to prevent fungal infections in chronic granulomatous disease has completed.