Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas [Phase 3]
Phase 3 clinical trial evaluating Glubran 2, a modified cyanoacrylate tissue adhesive, for use in soft pancreas during pancreatic and periam…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: A Study of MGC028 in Participants With Advanced Solid Tumors [Phase 1]
Clinical trial update for MGC028 in participants with advanced solid tumors. This Phase 1 study is currently recruiting to evaluate safety a…
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CLINICAL_TRIALS withdrawal · 2025-09-11Clinical Trial Update: A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies [Phase 2]
A Phase II clinical trial investigating adjuvant immunotherapy targeting KRAS G12D, KRAS G12V, and TP53 R175H across several gastrointestina…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Real-World Study of Precision Treatment for Advanced Cholangiocarcinoma Based on Molecular Subtyping
A real-world study is investigating precision treatment for advanced cholangiocarcinoma based on molecular subtyping, and the study has not …
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers [Phase 2]
Phase 2 trial evaluating tucatinib plus trastuzumab with oxaliplatin-based chemotherapy or pembrolizumab-containing regimens for HER2-positi…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Hilar Cholangiocarcinoma. A Prospective Multicenter Study.
A prospective multicenter study of liver transplantation combined with neoadjuvant chemo-radiotherapy for unresectable hilar cholangiocarcin…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)
This clinical trial POELH-III evaluates preoperative evaluation of lymph nodes in cholangiocarcinoma and is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Study of Large Channel Digital Pancreaticobiliary Scope (DPS) With Compatible Accessories [Phase 4]
Phase 4 study evaluating a Large Channel Digital Pancreaticobiliary Scope (DPS) with compatible accessories is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Volume-Restricted Resection for Perihilar Cholangiocarcinoma
This clinical trial update describes a study on volume-restricted resection for perihilar cholangiocarcinoma. It notes that enrollment has n…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Gavo-cel (TC-210), a mesothelin-targeted therapy, in patients with advanced mesothelin-expressing cancer…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
A Phase 1/2 study of TC-510 from TCR2 Therapeutics in mesothelin-expressing cancers is active but not recruiting, spanning multiple indicati…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Biomarker Discovery in Patients With Advanced Biliary Tract Cancer
A completed clinical trial update describing biomarker discovery efforts in patients with advanced biliary tract cancer, including cholangio…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: The Future Management of Patients With Neoplasms of the Gastro-intestinal Tract [NA]
This clinical trial update describes a study on the future management of gastrointestinal tract cancers, including pancreatic adenocarcinoma…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Effect and Mechanism of ALPPS Operation on Liver Regeneration
This clinical trial update describes evaluating the effects and mechanisms of the ALPPS liver surgery on liver regeneration in patients with…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma [Phase 3]
Phase 3 trial evaluating pemigatinib versus chemotherapy in unresectable or metastatic cholangiocarcinoma was terminated.
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: A Single-arm, Multicenter, Exploratory Study of Adebrelimab Combined With Apatinib and Systemic Chemotherapy for Initially Unresectable Biliary Tract Cancer [Phase 2]
A Phase 2, single-arm, multicenter exploratory trial is evaluating Adebrelimab plus Apatinib and systemic chemotherapy for initially unresec…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of LY3039478 in participants with advanced or metastatic solid tumors was terminated. Results were posted on 2025-08-21.
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Study of TT-00420 (Tinengotinib) in Subjects With Cholangiocarcinoma Who Failed or Relapsed to Chemotherapy and FGFR Inhibitor [Phase 2]
Phase 2 study of TT-00420 (Tinengotinib) in metastatic cholangiocarcinoma patients who failed or relapsed after chemotherapy and FGFR inhibi…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: En Bloc Resection of the Liver and Pancreas With a "Non-touch" Technique Followed by Liver Transplantation to Improve the Overall Survival in Patients With Non-resectable Hilar Cholangiocarcinoma Beyond the Mayo Clinic Transplant Criteria [NA]
This clinical trial update outlines a surgical strategy of en bloc resection of the liver and pancreas using a non-touch technique, followed…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer [Phase 2]
Phase 2 trial evaluating preoperative combination therapy with gemcitabine, cisplatin, and nab-paclitaxel for resectable cholangiocarcinoma,…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Acceptance and Commitment Therapy (ACT-HBC) for the Improvement of Cancer Distress in Patients With Hepatobiliary Cancers [NA]
Mayo Clinic is recruiting for a study of Acceptance and Commitment Therapy for reducing cancer-related distress in patients with malignant h…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Improving a Bile Duct Drainage Procedure in Patients With Inoperable Cancer Blocking the Bile Ducts: Comparing Two Types of Endoscopically Placed Internal Stents to Prevent Blockage of a Lumen Apposing Metal Stent [NA]
A clinical trial update describes a study comparing two endoscopically placed internal stents to prevent blockage of a lumen-apposing metal …
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma
This clinical trial update notes that the study evaluating preoperative lymph node evaluation in cholangiocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: The Safety and Efficacy of Benmelstobart Injection in Patients With Advanced Biliary Tract Malignant Tumors [Phase 2]
A Phase 2 clinical trial is evaluating Benmelstobart Injection for advanced biliary tract cancers and the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Non-invasive Diffusion-weighted Imaging With MRCP in the Diagnosis of Neoplastic Biliary Obstruction
A clinical trial evaluating non-invasive diffusion-weighted imaging with MRCP to diagnose neoplastic biliary obstruction.