Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-11Clinical Trial Results: A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma [Phase 3]
Phase 3 trial comparing pemigatinib to chemotherapy in unresectable or metastatic cholangiocarcinoma has terminated with results posted.
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CLINICAL_TRIALS trial_result · 2026-07-13Clinical Trial Results: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
Phase 1/2 trial results for TC-510 in advanced mesothelin-expressing cancers were terminated with posted results.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers [Phase 1, Phase 2]
The document describes an ongoing Phase 1/2 trial evaluating tivozanib for biliary tract cancers and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio [Phase 2]
Phase 2 clinical trial evaluating Yttrium-90 radioembolization combined with durvalumab, gemcitabine, and cisplatin for intrahepatic cholang…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
The update details a study to collect solid tumor tissue from people undergoing biopsy or surgery for colorectal, gastric, cholangiocarcinom…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations [Phase 1]
Phase 1 study of LY3410738 in patients with IDH1/IDH2-mutant advanced solid tumors, including cholangiocarcinoma, chondrosarcoma, and glioma…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of PHST001 in Advanced Solid Tumors [Phase 1]
Pheast Therapeutics is recruiting for a Phase 1 study of PHST001 in patients with advanced solid tumors, including ovarian cancer, endometri…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer
Clinical trial update on a precision-based immunotherapy program for primary liver cancer, currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of CGT4859, an FGFR2/3 inhibitor, for intrahepatic cholangiocarcinoma, cholangiocarcinoma, and other advanced solid tumors; …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of LY4337713 in Participants With FAP-Positive Solid Tumors [Phase 1]
A Phase 1 clinical trial update for LY4337713 in participants with FAP-positive solid tumors; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Molecular Epidemiology of Biliary Tree Cancers
This ClinicalTrials.gov study update notes that a trial on the molecular epidemiology of biliary tree cancers is currently recruiting, led b…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function [Phase 1]
Phase 1 study evaluating radiation therapy for patients with hepatocellular carcinoma, cholangiocarcinoma, or liver metastases who have impa…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Agnostic Therapy in Rare Solid Tumors [Phase 2]
A Phase 2 trial of an agnostic therapy for multiple rare solid tumors is currently recruiting. The study lists a broad set of tumor types ac…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Phase II Study of Iparomlimab and Tuvonralimab (QL1706) in Combination With Albumin-Bound Paclitaxel and Lenvatinib as Second-Line Therapy for Unresectable or Metastatic Biliary Tract Cancer [Phase 2]
A Phase II clinical trial is evaluating iparomlimab and tuvonralimab (QL1706) in combination with albumin-bound paclitaxel and lenvatinib as…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer [Phase 2]
This Phase 2 trial evaluates whether chemotherapy with atezolizumab is superior to chemotherapy with bevacizumab and atezolizumab in patient…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies [Phase 1, Phase 2]
This Clinical Trial Update describes a Phase 1/2 study of the ATR inhibitor peposertib in combination with the PD-L1 inhibitor avelumab and …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Clinical Effectiveness of Microwave Ablation Using Starwave Microwave Generator for Hepatic Malignancies [NA]
A clinical trial update indicates a study evaluating microwave ablation with the Starwave Microwave Generator for hepatic malignancies is cu…
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CLINICAL_TRIALS withdrawal · 2026-04-13Clinical Trial Update: Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ Needle [NA]
A clinical trial comparing Beacon BNX EUS-Needle vs SharkCore Needle has been withdrawn. The study involved pancreatic cancer, lymphadenopat…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors [Phase 2]
Phase 2 trial evaluating the combination of olaparib and AZD6738 in IDH1/IDH2-mutant tumors, including refractory cholangiocarcinoma; result…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced Cholangiocarcinoma [Phase 2]
A Phase 2 trial evaluating the PD-1 inhibitor Pucotenlimab combined with the EGFR-ADC Becotatugvedotin for advanced cholangiocarcinoma; the …
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Comparing the TDTP-RECIST With RECIST 1.1 and Other Volumetric Evaluation Methods for Assessing the Therapeutic Efficacy of Irregular Malignant Tumors
A completed study comparing TDTP-RECIST with RECIST 1.1 and other volumetric methods to evaluate therapeutic response in irregular malignant…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract Cancer [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of a combination therapy—gemcitabine/cisplatin (GemCis) with trastuzumab and …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: MP0317 in Combination With Chemoimmunotherapy in First Line Treatment for Patients With Advanced Biliary Tract Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating MP0317 in combination with chemoimmunotherapy as first-line treatment for advanced biliary tract carcino…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma [Phase 2]
This update describes a Phase 2 trial evaluating durvalumab, bevacizumab, tremelimumab plus transarterial chemoembolization for hepatocellul…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Phase II Study Evaluating Ivosidenib Maintenance After SOC Adjuvant Chemotherapy in Curative mIDH1 Cholangiocarcinoma [Phase 2]
Phase II study evaluating maintenance therapy with ivosidenib after standard-of-care adjuvant chemotherapy in curative IDH1-mutant cholangio…