Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: PULSAR Combined With Immunotherapy and Chemotherapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating PULSAR in combination with immunotherapy and chemotherapy for cholangiocarcinoma is currently recruiti…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA
A clinical trial is evaluating anti-PD-1/PD-L1 antibodies in combination with gemcitabine and cisplatin for advanced cholangiocarcinoma, and…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Phase I/II Study: Allogeneic NK-cell Therapy With Chemotherapy for Post-Surgery PDA or Cholangiocarcinoma Patients [Phase 1, Phase 2]
Phase I/II clinical trial evaluating allogeneic NK-cell therapy with chemotherapy for patients after surgical resection of pancreatic ductal…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Diagnostic Approach for Cholangiocarcinoma Using Liquid Bile Biopsy
This ClinicalTrials.gov study, conducted by University Hospital, Bordeaux, is recruiting to evaluate a liquid bile biopsy-based diagnostic a…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Intravital Microscopy in Human Solid Tumors [NA]
Mayo Clinic is conducting a clinical trial using intravital microscopy in multiple solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer [Phase 1]
A Phase 1 clinical trial evaluating chemoimmunotherapy combined with hyperthermia and spatially-fractionated radiotherapy in advanced biliar…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: A Phase 2 Study of Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation [Phase 2]
Phase 2 study of Ivosidenib in Japanese patients with nonresectable or metastatic IDH1-mutant cholangiocarcinoma. Results were posted on 202…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Pembrolizumab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 trial is examining pembrolizumab alone or with lenvatinib or chemotherapy as first-line treatment for advanced biliary tract cance…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Trop2-targeted immunoPET Imaging of Solid Tumors [Phase 2, Phase 3]
Clinical trial update for Trop2-targeted immunoPET imaging of solid tumors, currently in Phase 2/3 and recruiting.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer [Phase 1]
Phase 1 trial evaluating the combination of guadecitabine and durvalumab in advanced cholangiocarcinoma, gallbladder cancer, hepatocellular …
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Senior Adult Hepatobiliary Prehab Study [NA]
This update covers the Senior Adult Hepatobiliary Prehab Study, a trial in hepatobiliary cancer including cholangiocarcinoma; the study stat…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver Injury [NA]
A mechanistic clinical trial evaluating the protective and regenerative effects of Spirulina on hepatectomy-related liver injury in cholangi…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers [Phase 2]
Phase 2 perioperative regimen of gemcitabine, cisplatin, and pembrolizumab for potentially resectable biliary tract cancers; sponsored by Jo…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer
This clinical trial update describes a noninvasive miRNA-based test being explored for screening gastrointestinal cancers. It is currently r…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Ivosidenib in Locally Advanced or Metastatic Cholangiocarcinoma With IDH1 R132 Mutation After at Least One Prior Systemic Treatment - an Observational Study
An observational study evaluating the use of ivosidenib for locally advanced or metastatic cholangiocarcinoma with IDH1 R132 mutation after …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: A Study of GV20-0251 in Advanced or Refractory Solid Tumors [Phase 1]
This Phase 1 clinical trial update indicates that GV20-0251 is being studied in advanced or refractory solid tumors and is currently recruit…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies [NA]
A clinical trial is evaluating high dose-rate brachytherapy for unresectable primary and metastatic liver malignancies. The study is current…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors [Phase 1, Phase 2]
Phase I/II trial of autologous T cells engineered to express T-cell receptors (TCRs) in patients with solid tumors was terminated with resul…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating a recombinant EphB4-HSA fusion protein in combination with standard chemotherapy for advanced or metastatic solid t…
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EMA approval · 2025-10-29EMA Authorised: Lytgobi (Futibatinib) — Taiho Pharma Netherlands B.V.
EU authorises Lytgobi (futibatinib) for cholangiocarcinoma with conditional approval.
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies [Phase 1]
Open-label Phase 1 safety and tolerability study of INCB062079 in patients with advanced hepatocellular carcinoma and other malignancies; st…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: In-Depth Characterisation of Biliary Strictures and Hepato-Pancreato-Biliary Focal Lesions for Development of New Technologies to Tackle Hepato-Pancreato-Biliary Cancers
This clinical trial protocol from the University of Nottingham aims to characterize biliary strictures and hepatobiliary–pancreatic focal le…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer [Phase 2]
This clinical trial update notes the completion of a phase 2 study evaluating nanoliposomal irinotecan (nal-IRI) with either 5-fluorouracil/…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: EchoTip AcuCore Post-Market Clinical Study
Completed post-market clinical study update for the EchoTip AcuCore device, detailing the completion of the post-market evaluation.
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) [Phase 2]
Pembrolizumab is being studied in a Phase 2 trial (MK-3475-158/KEYNOTE-158) for advanced solid tumors; the study is currently active but not…