Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-11Clinical Trial Results: A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma [Phase 3]
Phase 3 trial comparing pemigatinib to chemotherapy in unresectable or metastatic cholangiocarcinoma has terminated with results posted.
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CLINICAL_TRIALS trial_result · 2026-07-13Clinical Trial Results: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
Phase 1/2 trial results for TC-510 in advanced mesothelin-expressing cancers were terminated with posted results.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations [Phase 1]
Phase 1 study of LY3410738 in patients with IDH1/IDH2-mutant advanced solid tumors, including cholangiocarcinoma, chondrosarcoma, and glioma…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of CGT4859, an FGFR2/3 inhibitor, for intrahepatic cholangiocarcinoma, cholangiocarcinoma, and other advanced solid tumors; …
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Phase II Study of Iparomlimab and Tuvonralimab (QL1706) in Combination With Albumin-Bound Paclitaxel and Lenvatinib as Second-Line Therapy for Unresectable or Metastatic Biliary Tract Cancer [Phase 2]
A Phase II clinical trial is evaluating iparomlimab and tuvonralimab (QL1706) in combination with albumin-bound paclitaxel and lenvatinib as…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies [Phase 1, Phase 2]
This Clinical Trial Update describes a Phase 1/2 study of the ATR inhibitor peposertib in combination with the PD-L1 inhibitor avelumab and …
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors [Phase 2]
Phase 2 trial evaluating the combination of olaparib and AZD6738 in IDH1/IDH2-mutant tumors, including refractory cholangiocarcinoma; result…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced Cholangiocarcinoma [Phase 2]
A Phase 2 trial evaluating the PD-1 inhibitor Pucotenlimab combined with the EGFR-ADC Becotatugvedotin for advanced cholangiocarcinoma; the …
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Comparing the TDTP-RECIST With RECIST 1.1 and Other Volumetric Evaluation Methods for Assessing the Therapeutic Efficacy of Irregular Malignant Tumors
A completed study comparing TDTP-RECIST with RECIST 1.1 and other volumetric methods to evaluate therapeutic response in irregular malignant…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract Cancer [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of a combination therapy—gemcitabine/cisplatin (GemCis) with trastuzumab and …
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients [Phase 1]
Phase 1 trial of Cabotamig (ARB202) in advanced gastrointestinal cancers has completed; no specific efficacy results are provided in the doc…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Activity of Regorafenib in Combination With Chemotherapy in Patients With Advanced Biliary Tract Cancer [Phase 1, Phase 2]
This clinical trial update reports activity of regorafenib in combination with chemotherapy in patients with advanced biliary tract cancer a…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) [Phase 2]
Phase 2 basket study evaluating entrectinib in solid tumors harboring NTRK1/2/3, ROS1, or ALK gene rearrangements; the study is listed as Ac…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors [Phase 1]
A Phase 1 study of CF33-hNIS (VAXINIA), an oncolytic virus, given alone or with pembrolizumab, in adults with metastatic or advanced solid t…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Study of E7090 in Participants With Unresectable Advanced or Metastatic Cholangiocarcinoma With Fibroblast Growth Factor Receptor (FGFR) 2 Gene Fusion [Phase 2]
A Phase 2 trial of futibatinib (E7090) in unresectable or metastatic cholangiocarcinoma with FGFR2 gene fusion has completed. Sponsor: Eisai…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors [Phase 1, Phase 2]
A first-in-human study of RLY-4008, a highly selective FGFR2 inhibitor, in intrahepatic cholangiocarcinoma and other advanced solid tumors h…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation [Phase 1]
Phase 1 study of AG-120 (ivosidenib) for IDH1-mutant advanced solid tumors, including glioma, has completed enrollment and data collection.
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Ivosidenib, Nivolumab, and Ipilimumab Combination in Previously Treated Subjects With Nonresectable or Metastatic IDH1 Mutant Cholangiocarcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating the triple combination of ivosidenib, nivolumab, and ipilimumab in previously treated nonresectable or metastat…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma [Phase 2]
Phase 2 trial evaluating delivery of chemotherapy to patients with colorectal cancer or cholangiocarcinoma using the Medtronic Pump and Codm…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease [Phase 1]
AU409 is being evaluated in a Phase 1 trial for advanced cholangiocarcinoma and hepatocellular carcinoma, including patients with stage III/…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Comparison of Two Seed Strand Implantation Techniques for Biliary Cancer [NA]
Clinical trial update reporting a completed study comparing two seed strand implantation techniques for biliary cancer.
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy
Terminated clinical trial evaluating the clinical utility of selected circulating tumor DNA assays in patients with advanced malignancies, s…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Nivolumab Plus Relatlimab and Gemcitabine/Cisplatin as First-Line Treatment in Advanced Biliary Tract Cancer. [Phase 2]
Phase 2 trial evaluating nivolumab plus relatlimab with gemcitabine/cisplatin as first-line treatment for advanced biliary tract cancer; the…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar Cholangiocarcinoma
Completed clinical trial comparing the diagnostic efficacy of endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/B) versus …
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers [Phase 2]
Phase 2 study evaluating the PET imaging agent [18F]FAPI-74 in gastrointestinal cancers has completed.