Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of trifluridine/tipiracil with oxaliplatin for advanced or metastatic biliary tract cancer…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma [Phase 3]
An early access (compassionate use) study of ivosidenib for patients with pretreated cholangiocarcinoma (locally advanced or metastatic) is …
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation [Phase 1]
Phase 1 study of AG-120 (ivosidenib) for IDH1-mutant advanced solid tumors, including glioma, has completed enrollment and data collection.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Biobank for Cholestatic Liver Diseases.
Mayo Clinic is recruiting for a biobank study of cholestatic liver diseases, including primary sclerosing cholangitis and primary biliary ch…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
A Mayo Clinic-sponsored study aims to characterize biliary cell-derived organoids from bile samples of patients with primary sclerosing chol…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study [Phase 2]
A Phase 2 trial (The Knight SHIFT Study) is comparing morning versus afternoon administration of immunotherapy for advanced or metastatic so…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Ivosidenib, Nivolumab, and Ipilimumab Combination in Previously Treated Subjects With Nonresectable or Metastatic IDH1 Mutant Cholangiocarcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating the triple combination of ivosidenib, nivolumab, and ipilimumab in previously treated nonresectable or metastat…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma [Phase 1]
Phase 1 trial update for SynKIR-110 in mesothelin-expressing ovarian cancer, cholangiocarcinoma, and mesothelioma, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma [Phase 2]
Phase 2 trial evaluating delivery of chemotherapy to patients with colorectal cancer or cholangiocarcinoma using the Medtronic Pump and Codm…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers [Phase 1]
Phase 1 exploratory study evaluating FAPi PET/CT imaging with histopathology validation in patients with various cancers. The trial collects…
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CLINICAL_TRIALS other · 2026-02-05Clinical Trial Update: The PLATON Network
The PLATON Network trial (NCT05489250), sponsored by IKF GmbH at Krankenhaus Nordwest, has been terminated; the study involved hepatocellula…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Evaluation of the Safety, Tolerability and Efficacy of iNeo-Vac-R01, an Individualized mRNA Therapeutic Technology Based on Tumor Neoantigens, for Adjuvant Treatment in Patients With Biliary Malignant Tumors After Radical Resection [Phase 1, Phase 2]
This clinical trial update reports ongoing Phase 1/2 evaluation of iNeo-Vac-R01, an individualized mRNA neoantigen vaccine, as adjuvant ther…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease [Phase 1]
AU409 is being evaluated in a Phase 1 trial for advanced cholangiocarcinoma and hepatocellular carcinoma, including patients with stage III/…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Comparison of Two Seed Strand Implantation Techniques for Biliary Cancer [NA]
Clinical trial update reporting a completed study comparing two seed strand implantation techniques for biliary cancer.
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy
Terminated clinical trial evaluating the clinical utility of selected circulating tumor DNA assays in patients with advanced malignancies, s…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Nivolumab Plus Relatlimab and Gemcitabine/Cisplatin as First-Line Treatment in Advanced Biliary Tract Cancer. [Phase 2]
Phase 2 trial evaluating nivolumab plus relatlimab with gemcitabine/cisplatin as first-line treatment for advanced biliary tract cancer; the…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating BOLD-100 in combination with FOLFOX for advanced solid tumors, including colorectal cancer, pancreatic…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar Cholangiocarcinoma
Completed clinical trial comparing the diagnostic efficacy of endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/B) versus …
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC) [Phase 2]
Phase 2 clinical trial assessing a four-drug combination (gemcitabine, cisplatin, AB680, AB122) as first-line therapy for advanced biliary t…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers [Phase 2]
Phase 2 study evaluating the PET imaging agent [18F]FAPI-74 in gastrointestinal cancers has completed.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a combination of GNS561 and trametinib in advanced KRAS-mutated cholangiocarcinoma is currently recrui…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia
A Zhejiang University-sponsored clinical trial (NCT07359586) is currently recruiting to evaluate laryngopharyngeal injury after endotracheal…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating MK-2870 alone or with other therapies for gastrointestinal cancers is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Brightline-2: A Study to Test Whether Brigimadlin (BI 907828) Helps People With Cancer in the Biliary Tract, Pancreas, Lung or Bladder [Phase 2]
Phase 2 study update on brigimadlin (BI 907828) in biliary tract cancer, pancreatic cancer, lung cancer, and bladder cancer; the trial has c…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Pembrolizumab in Combination With Lenvatinib in Patients With Advanced Biliary Tract Carcinoma [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with lenvatinib for advanced biliary tract carcinoma. The study has completed.