Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies [Phase 4]
Phase 4 trial evaluating olutasidenib for drug-drug interaction in IDH1-mutant malignancies. The study is currently recruiting in AML, gliom…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients [Phase 1]
Phase 1 trial of Cabotamig (ARB202) in advanced gastrointestinal cancers has completed; no specific efficacy results are provided in the doc…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Investigation of Predictive Biomarkers in Patients With Advanced BTC Treated With Lenvatinib Plus Pembrolizumab
Clinical trial update describing investigation of predictive biomarkers in patients with advanced biliary tract cancer treated with lenvatin…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Vebotolimab Combined With Ptorlimab for EGFR-positive Refractory Advanced Biliary Tract Malignancies [Phase 2]
A Phase 2 clinical trial evaluating the combination of vebotolimab and Ptorlimab for EGFR-positive advanced biliary tract cancers is not yet…
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EMA approval · 2026-03-17EMA Authorised: Pemazyre (pemigatinib) — Incyte Biosciences Distribution B.V.
The European Medicines Agency authorised Pemazyre (pemigatinib) for cholangiocarcinoma with conditional approval and orphan medicine designa…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: FAPI-PET Value for the Initial Screening of Pancreatic and Biliary Cancers [Phase 2]
A Phase 2 study investigating the use of FAPI-PET imaging for initial screening of cholangiocarcinoma and pancreatic adenocarcinoma, status …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Liquid Biopsy MonitORing Of CholangioCarcinOma for Treatment Response and Prognostic Outcomes (MOROCCO)
A Mayo Clinic study named MOROCCO is evaluating liquid biopsy-based monitoring to assess treatment response and prognosis in cholangiocarcin…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Detecting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma (LyMIC)
A completed clinical trial (LyMIC) studying detection of lymph node metastasis in intrahepatic cholangiocarcinoma. The trial was sponsored b…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Activity of Regorafenib in Combination With Chemotherapy in Patients With Advanced Biliary Tract Cancer [Phase 1, Phase 2]
This clinical trial update reports activity of regorafenib in combination with chemotherapy in patients with advanced biliary tract cancer a…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Clinical Study of TQB3454 Tablets in the Treatment of Advanced Biliary Carcinoma. [Phase 3]
Phase 3 clinical trial update for TQB3454 in advanced biliary carcinoma (cholangiocarcinoma), with status ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS approval · 2026-03-10Clinical Trial Update: Expanded Access Study of TAS-120 in Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements
Expanded Access study of TAS-120 (futibatinib) in patients with advanced cholangiocarcinoma harboring FGFR2 rearrangements, with the drug re…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: 18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant [Phase 1]
This clinical trial update describes a Phase 1 imaging study using 18F-FSPG PET to evaluate liver cancer in patients scheduled for liver res…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome
An ongoing clinical trial is recruiting to study the frequency and clinical phenotype of BAP1 tumor predisposition syndrome and its associat…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) [Phase 2]
Phase 2 basket study evaluating entrectinib in solid tumors harboring NTRK1/2/3, ROS1, or ALK gene rearrangements; the study is listed as Ac…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: TRACE-BTC. Relation of Biomarkers and Patients Reported Quality of Life to Outcomes in Patients With Biliary Tract Cancer: a Real- World Cohort
The TRACE-BTC study is a real-world cohort investigation examining how biomarkers and patient-reported quality of life relate to outcomes in…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors [Phase 1]
A Phase 1 study of CF33-hNIS (VAXINIA), an oncolytic virus, given alone or with pembrolizumab, in adults with metastatic or advanced solid t…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01) [Phase 3]
A Phase 3 trial evaluating rilvegostomig combined with chemotherapy as adjuvant therapy after surgical resection for biliary tract cancer is…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of AK130 in combination with AK112 for advanced biliary tract cancer, currently rec…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Study of E7090 in Participants With Unresectable Advanced or Metastatic Cholangiocarcinoma With Fibroblast Growth Factor Receptor (FGFR) 2 Gene Fusion [Phase 2]
A Phase 2 trial of futibatinib (E7090) in unresectable or metastatic cholangiocarcinoma with FGFR2 gene fusion has completed. Sponsor: Eisai…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors [Phase 1, Phase 2]
A first-in-human study of RLY-4008, a highly selective FGFR2 inhibitor, in intrahepatic cholangiocarcinoma and other advanced solid tumors h…
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EMA approval · 2026-02-25EMA Authorised: Tibsovo (Ivosidenib) — Les Laboratoires Servier
The European Medicines Agency authorised Tibsovo (ivosidenib) for acute myeloid leukemia and cholangiocarcinoma in the EU, with Les Laborato…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating sacituzumab govitecan for locally advanced, recurrent, or metastatic cholangiocarcinoma is currently act…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers [NA]
A pilot study comparing two ctDNA sampling methods (ctDNA IDV vs SPV) in patients undergoing biopsies for hepatobiliary and pancreatic cance…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes [NA]
Cedars-Sinai Medical Center is recruiting for a study evaluating virtual reality to manage gastrointestinal cancer pain and improve patient-…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations [Phase 2]
This Clinical Trial Update reports on a Phase 2 study of olaparib in patients with advanced glioma, cholangiocarcinoma, or other IDH1/IDH2-m…