Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-01-28Clinical Trial Update: Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers [Phase 3]
Phase 3 trial comparing active symptom control alone versus with mFOLFOX chemotherapy for locally advanced or metastatic biliary tract cance…
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CLINICAL_TRIALS trial_result · 2020-01-09Clinical Trial Update: Metformin And Chloroquine in IDH1/2-mutated Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial investigating metformin and chloroquine in IDH1/2-mutated solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2019-12-09Clinical Trial Update: Clinical Study on the First-line Treatment of Advanced Biliary System Tumors With Tripley Monoclonal Antibody Combined With GEMOX Regimen [Phase 2]
Phase 2 clinical trial evaluating Tripley monoclonal antibody combined with GEMOX as first-line treatment for advanced biliary tract tumors.
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CLINICAL_TRIALS trial_result · 2019-10-30Clinical Trial Update: Study of TQB2450 Combined With Anlotinib in Subjects With Advanced Cholangiocarcinoma [Phase 1, Phase 2]
A clinical trial evaluating TQB2450 in combination with Anlotinib in advanced cholangiocarcinoma (Phase 1/2) with status not disclosed.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Efficacy and Safety Study of Nab-Paclitaxel Combined With Cisplatin in Second or Later-Line Treatment in Advanced Biliary Tract Cancers [Phase 2]
Phase 2 trial evaluating nab-paclitaxel with cisplatin in advanced biliary tract cancers; efficacy and safety updates are reported.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: TAS-102 in Treating Advanced Biliary Tract Cancers [Phase 2]
A Phase 2 clinical trial update for TAS-102 in advanced biliary tract cancers (cholangiocarcinoma and gallbladder cancer) has completed with…
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CLINICAL_TRIALS trial_result · 2019-08-30Clinical Trial Update: Trial of Therapeutic Vaccine in Patients With Cholangiocarcinoma [Phase 1, Phase 2]
A clinical trial update for a therapeutic vaccine in cholangiocarcinoma spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: Toripalimab Combined With Gemcitabine/5--fluoropyrimidine for Advanced Cholangiocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating toripalimab in combination with gemcitabine and 5-fluorouracil for advanced cholangiocarcinoma is underw…
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Study of Gemcitabine, Irinotecan and Panitumumab in Patients With Advanced and Metastatic Biliary Tract Adenocarcinoma [Phase 2]
Phase 2 trial investigating gemcitabine, irinotecan, and panitumumab in advanced/metastatic biliary tract adenocarcinoma completed with post…
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Evaluating Combination Immunotherapy for Advanced Cholangiocarcinoma With Pembrolizumab and PEG-Intron [Phase 2]
Phase 2 trial evaluating pembrolizumab plus PEG-Intron for advanced cholangiocarcinoma was terminated with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-05-21Clinical Trial Update: Study of GEMOX(Gemcitabine/Oxaliplatin) Versus XELOX(Xeloda/Oxaliplatin) in Advanced Biliary Tract Carcinoma [Phase 3]
Phase 3 trial comparing GEMOX to XELOX in advanced biliary tract cancer; status is unknown.
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CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating CPI-613 in advanced or metastatic biliary tract cancers, including cholangiocarcinoma and unresectable o…
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CLINICAL_TRIALS research · 2019-02-20Clinical Trial Update: Self-expandable Metal Stents Versus Multiple Plastic Stents for Palliation of Biliary Obstruction [NA]
A clinical trial comparing self-expandable metal stents with multiple plastic stents for palliation of biliary obstruction; the current stat…
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Pathogenesis of Liver Fluke Induced Cancer in Thailand
Completed clinical trial update investigating the pathogenesis of liver fluke–associated cancer in Thailand, focusing on Opisthorchis viverr…
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy [Phase 2]
This update reports results from a Phase 2 single-agent trial of regorafenib in patients with advanced or metastatic biliary tract carcinoma…
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: Efficacy and Safety of Endobiliary Radiofrequency Ablation by Using a Novel RF Catheter (ELRA®) on Maintaining the Patency of Endobiliary Metal Drainage in Patients With Malignant Biliary Strictures : A Double-arm Comparable Study [NA]
This clinical trial update discusses the efficacy and safety of a novel endobiliary radiofrequency ablation catheter (ELRA) used to maintain…
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CLINICAL_TRIALS research · 2019-01-28Clinical Trial Update: A Study for Efficacy of Side-by-side Compared to Stent-in-stent Technique in the Endoscopic Management of Malignant Hilar Biliary Obstruction [NA]
A clinical trial comparing side-by-side versus stent-in-stent techniques for malignant hilar biliary obstruction. The study lists cholangioc…
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Adjuvant Chemotherapy for Biliary Tract Cancer After Curative Resection [Phase 3]
Phase 3 clinical trial investigating adjuvant chemotherapy after curative resection for biliary tract cancer.
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CLINICAL_TRIALS research · 2018-06-06Clinical Trial Update: Process Optimization of Preoperative Biliary Drainage in Patients With Malignant Obstructive Jaundice [NA]
A clinical trial update describing methods to optimize preoperative biliary drainage in patients with malignant obstructive jaundice.
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: ASLAN001 in Patients With Advanced or Metastatic Cholangiocarcinoma Who Progressed on at Least 1 Line of Systemic Therapy [Phase 2]
Phase 2 trial of ASLAN001 in advanced or metastatic cholangiocarcinoma that progressed after at least one prior systemic therapy has complet…
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Phase II Trial of Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Cholangiocarcinoma [Phase 2]
Phase II trial evaluating nab-paclitaxel plus gemcitabine as first-line therapy for cholangiocarcinoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-15Clinical Trial Update: Colonization of Bile Ducts and Postoperative Infectious Complications of Pancreaticoduodenectomies
This completed clinical trial update investigates bile duct colonization and postoperative infectious complications after pancreaticoduodene…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Efficacy Study of Intra-hepatic Administration of Therasphere® in Association With Intravenous Chemotherapy to Treat Cholangiocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating intra-hepatic administration of TheraSphere in combination with intravenous chemotherapy for cholangioca…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Precise Treatment System of Biliary Malignancies Based on Special Disease Database
An ongoing clinical trial update describes a precision treatment system for biliary malignancies using a disease-specific database, sponsore…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: A Phase II Trial of LDK378 in ROS1 and /or ALK Over-expressed Advanced Intrahepatic or Hilar Cholangiocarcinoma [Phase 2]
A Phase II trial of ceritinib (LDK378) for ROS1/ALK-overexpressed advanced intrahepatic or hilar cholangiocarcinoma has been terminated. The…