Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-12-16Clinical Trial Update: A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma [Phase 2]
A Phase 2 trial evaluated entinostat in combination with nivolumab in patients with previously treated unresectable or metastatic cholangioc…
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CLINICAL_TRIALS trial_result · 2021-12-10Clinical Trial Update: A Study of MRG002 in the Treatment of HER2-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial update for MRG002 in HER2-positive biliary tract cancer (advanced/metastatic, unresectable).
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CLINICAL_TRIALS trial_result · 2021-12-08Clinical Trial Update: RALOX as Second Line Treatment for Advanced Malignant Biliary System Tumor [Phase 2]
Phase II trial update for RALOX as second-line treatment in advanced malignant biliary system tumors, status not disclosed.
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: SHR-1210 in Combination With GEMOX in Patients With Advanced BTC [Phase 2]
Phase 2 trial of SHR-1210 combined with GEMOX in advanced biliary tract cancer and cholangiocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2021-10-22Clinical Trial Update: Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangiocarcinoma [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating CX-4945 in combination with gemcitabine and cisplatin for frontline treatment of cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2021-10-15Clinical Trial Update: Personal Resilience Empowerment Program Study [NA]
Clinical trial update for a study titled Personal Resilience Empowerment Program; status completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-09-01Clinical Trial Update: Neoadjuvant mFOLFOXIRI for Potentially Resectable Cholangiocarcinoma [Phase 2]
Phase 2 trial update exploring neoadjuvant mFOLFOXIRI for potentially resectable cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2021-06-04Clinical Trial Update: Lenvatinib in Patients With Previously Treated Advanced Biliary Tract Cancer [Phase 2]
Phase 2 trial update of lenvatinib in previously treated advanced biliary tract cancer shows completed status; investigational targeted ther…
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CLINICAL_TRIALS trial_result · 2021-06-03Clinical Trial Update: Apatinib Plus Camrelizumab in Patients With Previously Treated Advanced Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial evaluating apatinib plus camrelizumab in previously treated advanced biliary tract cancer shows completed status.
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CLINICAL_TRIALS trial_result · 2021-04-15Clinical Trial Update: Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in People With Advanced Biliary Tract Carcinoma (BTC) [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with CAPOX for advanced biliary tract cancer has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-26Clinical Trial Update: A Pilot Study to Assess Theragnostically Planned Liver Radiation to Optimize Radiation Therapy [NA]
Pilot study assessing theragnostically planned liver radiation to optimize radiation therapy for liver cancer, completed with posted results…
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FDA approval · 2021-02-23FDA Approved: PEMAZYRE — Supplemental Application (Incyte Corporation)
The FDA approved a supplemental application for Pemazyre (pemigatinib) from Incyte Corporation.
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: Trastuzumab in HER2-positive Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial of trastuzumab in HER2-positive biliary tract cancer has completed.
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CLINICAL_TRIALS trial_result · 2020-12-21Clinical Trial Update: A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma [Phase 2]
Phase 2 trial investigating use of a Medtronic pump and Codman catheter to deliver chemotherapy in colorectal cancer and cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2020-12-02Clinical Trial Update: mFOLFOX vs. mFOLFIRI in Advanced or Recurrent Biliary Tract Cancer Refractory to First Line [Phase 2]
Phase 2 trial comparing mFOLFOX vs. mFOLFIRI in advanced or recurrent biliary tract cancer refractory to first-line therapy has completed.
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CLINICAL_TRIALS trial_result · 2020-11-17Clinical Trial Update: First Line Gemcitabine, Cisplatin and MEK162 in Advanced Biliary Tract Carcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating first-line gemcitabine, cisplatin, and MEK162 in advanced biliary tract carcinoma has completed with results po…
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: Copanlisib (BAY 80-6946) in Combination With Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma [Phase 2]
Phase 2 trial of copanlisib in combination with gemcitabine and cisplatin for advanced cholangiocarcinoma completed.
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CLINICAL_TRIALS trial_result · 2020-10-05Clinical Trial Update: Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Cholangiocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating intra-hepatic chemotherapy for non-resectable liver metastases from cholangiocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic Cholangiocarcinoma [Phase 2]
Phase II trial investigating dasatinib in IDH-mutant advanced intrahepatic cholangiocarcinoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: Regorafenib Versus Placebo to Treat Cholangiocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating regorafenib versus placebo for cholangiocarcinoma is reported, status unknown.
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CLINICAL_TRIALS trial_result · 2020-07-29Clinical Trial Update: Gemcitabine + Oxaliplatin +Nab-paclitaxel in Subjects With Advanced Biliary Tract Cancer [Phase 1, Phase 2]
Clinical trial update for a combination therapy (gemcitabine + oxaliplatin + nab-paclitaxel) in advanced biliary tract cancer, including cho…
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FDA approval · 2020-04-17FDA Approved: PEMAZYRE — Original Application (Incyte Corporation)
FDA approval of Pemazyre (pemigatinib) from Incyte as an original application for the treatment of cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: Second Line Chemotherapy FOLFIRINOX in Irresectable Cholangiocarcinoma [Phase 2]
Phase 2 trial updating second-line chemotherapy FOLFIRINOX in unresectable cholangiocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2020-02-07Clinical Trial Update: Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in Participants With Previously Untreated, Unresectable, Locally Advanced, or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma [Phase 1]
Phase 1 trial evaluating PEGPH20 with cisplatin and gemcitabine, with or without atezolizumab, in previously untreated unresectable/metastat…
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CLINICAL_TRIALS trial_result · 2020-02-06Clinical Trial Update: Combined Biological Treatment and Chemotherapy for Patients With Inoperable Cholangiocarcinoma [Phase 2]
Phase 2 clinical trial update evaluating combined biological treatment and chemotherapy for patients with inoperable cholangiocarcinoma.