Cholangiocarcinoma
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Photodynamic Therapy for Cholangiocarcinoma [NA]
A completed clinical trial evaluating photodynamic therapy for non-resectable cholangiocarcinoma.
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Neo-adjuvant Chemo and Immunotherapy in the Pre-operAtive Treatment of Locally Advanced CholangIOcarciNoma [Phase 2]
A Phase 2 study evaluating neoadjuvant chemotherapy with immunotherapy before surgery for locally advanced cholangiocarcinoma is currently r…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: A Dual Channel Supraglottic Airway Device (LMA Gastro) for Oxygenation in Patients Undergoing ERCP [NA]
A completed clinical trial evaluated the LMA Gastro dual-channel supraglottic airway device for oxygenation during ERCP procedures.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Durvalumab and Tremelimumab With Platinum-based Chemotherapy in Intrahepatic Cholangiocarcinoma (ICC) [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of Durvalumab plus Tremelimumab with platinum-based chemotherapy for intra…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Primary Percutaneous Stenting Above the Ampulla Versus Endoscopic Drainage for Unresectable Malignant Hilar Biliary Obstruction [Phase 3]
A Phase 3 clinical trial comparing primary percutaneous stenting above the ampulla to endoscopic drainage for unresectable malignant hilar b…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: Spanish Registry of Quality Indicators and Adverse Events of Endoscopic Retrograde Cholangiopancreatography
This entry describes the Spanish Registry of Quality Indicators and Adverse Events for Endoscopic Retrograde Cholangiopancreatography (ERCP)…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Anlotinib Plus Nab-Paclitaxels and S-1 for Patients with Advanced Biliary Tract Cancer As Second-Line Treatment [Phase 2, Phase 3]
This document describes a Phase 2/Phase 3 clinical trial evaluating a combination of anlotinib with nab-paclitaxel and S-1 for second-line t…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: A Novel Serological Risk Model for Early Non-invasive Diagnosis of Cholangiocarcinoma
A clinical trial update describing a novel serological risk model for early, non-invasive diagnosis of cholangiocarcinoma, currently not yet…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: IDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid Tumor [Phase 1]
Phase 1 trial of AB-218, an IDH1 inhibitor, in advanced IDH1-mutant cholangiocarcinoma and other IDH1-mutant solid tumors has been terminate…
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CLINICAL_TRIALS research · 2024-10-10Clinical Trial Update: Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma [NA]
A clinical trial is investigating liver transplantation for patients with stable, advanced intrahepatic cholangiocarcinoma. Enrollment is by…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Outcomes and Prognostic Factors in Hepatopancreatoduodenectomy
A completed clinical trial from Seoul National University Hospital analyzes outcomes and prognostic factors for hepatopancreatoduodenectomy …
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CLINICAL_TRIALS research · 2024-10-03Clinical Trial Update: Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations [Phase 1]
TYRA-200 is being studied in a Phase 1 trial to assess safety and anti-tumor activity in advanced cholangiocarcinoma with FGFR2 alterations.…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors [Phase 1, Phase 2]
Phase 1/2 trial of BNT141 in CLDN18.2-positive gastric, pancreatic, ovarian, and biliary tract cancers. The study was terminated and results…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Oral Protein Supplements for Nutritional and Quality of Life Improvement After Pancreatic Resection in Elderly Patients [NA]
A completed clinical trial from Yonsei University evaluated whether oral protein supplements improve nutrition and quality of life after pan…
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig in Resectable iCCA [Phase 2]
Phase 2 trial update evaluating gemcitabine/cisplatin/nab-paclitaxel with rilvegostomig in resectable cholangiocarcinoma; currently not yet …
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: A Study of ZW25 (Zanidatamab) in Subjects With Advanced or Metastatic HER2-Amplified Biliary Tract Cancers [Phase 2]
Phase 2 study of Zanidatamab (ZW25) in advanced or metastatic HER2-amplified biliary tract cancers completed with results posted.
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Evaluation of Combined Modality Protons and Hepatic Transplantation for Hilar Cholangiocarcinoma [NA]
A clinical trial evaluating proton therapy combined with hepatic transplantation for hilar cholangiocarcinoma, currently not recruiting.
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: TCF-001 TRACK (Target Rare Cancer Knowledge) Study [NA]
Clinical trial update for TCF-001 TRACK study (Target Rare Cancer Knowledge) is currently recruiting. The study targets cholangiocarcinoma a…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Impact of Preoperative Endoscopic Ultrasound-guided Fine-needle Aspiration in Cholangiocarcinoma Patients
Clinical trial update describing a study assessing the impact of preoperative endoscopic ultrasound-guided fine-needle aspiration in cholang…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Pemigatinib Combined With Durvalumab for Previously Treated Biliary Tract Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating pemigatinib with durvalumab for previously treated biliary tract carcinoma is not yet recruiting.
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors [Phase 2]
Phase 2 clinical trial evaluating the combination of olaparib and durvalumab in IDH-mutated solid tumors, including glioma and cholangiocarc…
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer [Phase 2]
Phase II clinical trial evaluating SHR-A1811 in patients with HER2-expressing or HER2-amplified biliary tract cancer; recruitment is ongoing…
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Phase 2 Study: OBI-833/OBI-821 Maintenance for Globo H+ Advanced Biliary Tract Cancer After Gemcitabine/Cisplatin [Phase 1]
A Phase 2 maintenance trial of OBI-833 and OBI-821 for Globo H-positive advanced biliary tract cancer after gemcitabine/cisplatin is not yet…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: TACE Combined With Immune Checkpoint Inhibitors for Liver Malignant Tumors [NA]
This clinical trial assesses the combination of transarterial chemoembolization (TACE) with immune checkpoint inhibitors for non-resectable …
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma [Phase 2]
Phase 2 study evaluating tinengotinib (TT-00420) for cholangiocarcinoma has completed; no efficacy or safety results are provided in the sou…