Cholangiocarcinoma
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Chemotherapy Combined with Immunotherapy and Targeted Therapy in Cholangiocarcinoma
An ongoing clinical trial is evaluating a combination of chemotherapy, immunotherapy, and targeted therapy for cholangiocarcinoma, and is cu…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: First-line Trastuzumab, Gemcitabine, Cisplatin and Nivolumab in Advanced HER2- Positive Biliary Tract Cancer: a Multicenter, Open-label, Single-arm Phase Ib/II Trial (HERBOT) [Phase 1, Phase 2]
A multicenter, open-label Phase Ib/II trial evaluating first-line trastuzumab with gemcitabine and cisplatin plus nivolumab in HER2-positive…
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Cell-Surface Plectin in the Diagnosis of Cholangiocarcinoma from ERCP-directed Biliary Samples
This clinical trial is investigating cell-surface plectin as a diagnostic biomarker for cholangiocarcinoma using ERCP-derived biliary sample…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Neoadjuvant Gemcitabine Plus Cisplatin With or Without Durvalumab in Resectable Biliary Tract Cancer [Phase 2]
This Phase 2 trial evaluates neoadjuvant gemcitabine plus cisplatin, with or without durvalumab, in patients with resectable biliary tract c…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Donafenib Combined With Capecitabine for Postoperative Adjuvant Therapy of Biliary Malignant Tumors With High-risk Recurrence Risk [Phase 2]
Phase 2 trial evaluating donafenib in combination with capecitabine as postoperative adjuvant therapy for biliary tract cancer with high rec…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Feasibility of Cryobiopsy from the Bile Duct - CRYLEO [NA]
This completed clinical trial assessed the feasibility of performing cryobiopsy of the bile duct to sample neoplastic tissue.
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors [Phase 1]
Phase 1 study of ELI-002 in KRAS-mutated pancreatic ductal adenocarcinoma and other KRAS-driven solid tumors has completed enrollment, with …
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Phase 2 Trial of Adjuvant Adebrelimab Combined With Capecitabine in High-Risk Resected Cholangiocarcinoma: ACHIEVE [Phase 2]
Phase 2 ACHIEVE trial evaluating adjuvant combination of Adebrelimab (SHR-1316) and Capecitabine in high-risk resected cholangiocarcinoma; r…
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Intra Artherial Therapies in Treatment of Primary Liver Diseases: an Observational Study
An observational study evaluating intra-arterial therapies for primary liver diseases, including hepatocellular carcinoma and cholangiocarci…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: In This Study, a Retrospective Analysis Was Conducted to Explore the Risk Factors for Patients Undergoing Pancreaticoduodenal Surgery (PD) to Achieve TO, and a Nomogram Prediction Model Was Further Established to Promote the Standardization and Standardization of PD Surgical Quality Evaluation.
A retrospective study examined risk factors in patients undergoing pancreaticoduodenectomy and developed a nomogram to standardize PD surgic…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver [Phase 2]
Phase 2 clinical trial results update evaluating pevonedistat in combination with chemotherapy for biliary tract cancers (cholangiocarcinoma…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: TAS102 in Combination With NAL-IRI in Advanced GI Cancers [Phase 1, Phase 2]
This document provides an update on an ongoing Phase 1/2 clinical trial evaluating the combination of TAS-102 with nanoliposomal irinotecan …
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Feasibility Analysis of LCD-SLA 3D Printing Technology for Overall Surgical Planning of Liver Malignant Tumors [NA]
This completed clinical trial assessed the feasibility of LCD-SLA 3D printing to assist in overall surgical planning for liver malignant tum…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Study of Pembrolizumab and Olaparib in Bile Duct Cancer [Phase 2]
Phase 2 trial of pembrolizumab plus olaparib in cholangiocarcinoma has completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Long-term Morbidity After Surgery for Perihilar Cholangiocarcinoma
A completed clinical trial report examining long-term morbidity after surgery for perihilar cholangiocarcinoma, focusing on postoperative co…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms [NA]
This entry notes the completion of a clinical trial evaluating a comprehensive electronic cancer support system for managing cancer-related …
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Diagnostic Value of Next-Generation Sequencing Analysis in Biliary Tract Tumours [NA]
This clinical trial registry entry describes a study evaluating the diagnostic value of next-generation sequencing analysis in biliary tract…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Utidelone Capsule Monotherapy for Patients with Advanced Solid Tumors [Phase 2]
Phase 2 trial of Utidelone as monotherapy for advanced solid tumors, currently not recruiting.
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Prospective Evaluation of Biliary Tissue Sampling with ERCP
Prospective evaluation of biliary tissue sampling using ERCP is currently enrolling by invitation at Mayo Clinic.
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: GEMOX Combined With Targeted Therapy and Immunotherapy for Patients With Advanced Cholangiocarcinoma [NA]
A clinical trial is recruiting to assess GEMOX combined with targeted therapy and immunotherapy for advanced cholangiocarcinoma, sponsored b…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Robotically Assisted Surgery For Perihilar Cholangiocarcinoma: A Prospective Study
Prospective study evaluating robotically assisted surgery for perihilar cholangiocarcinoma is currently recruiting. Sponsored by Azienda Osp…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: An Artificial Intelligence System for ROSE of EUS-FNA Sample: a Prospective, Multicenter, Diagnostic Study.
This clinical trial update describes a prospective multicenter study evaluating an AI-assisted ROSE system for EUS-FNA samples to diagnose m…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Spanish Registry of Digestive Tumours RETUD
This entry notes the RETUD Spanish registry for digestive tumours is currently recruiting, sponsored by the Spanish Cooperative Group for th…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Phase Ⅱ Clinical Study of Surufatinib Combined With Gemcitabine and Cisplatin Plus Durvalumab/Pembrolizumab Regimen in the Treatment of Advanced Biliary Tract Cancer [Phase 2]
Phase II trial evaluates a combination of surufatinib with gemcitabine, cisplatin, and durvalumab or pembrolizumab for advanced biliary trac…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand [NA]
A McMaster University-sponsored clinical trial in Khon Kaen, Thailand is evaluating a community-based behaviour-change communication model t…