Chagas Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Prospective Study of Benznidazole for Chagas' Disease Children With Chronic Indeterminate Chagas Disease [Phase 3]
A Phase 3 clinical trial is evaluating benznidazole for children with chronic indeterminate Chagas disease; the trial is currently active bu…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health
An observational pregnancy safety study to evaluate outcomes in women exposed to nifurtimox during pregnancy for Chagas disease; the trial s…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Short-course Benznidazole Treatment to Reduce Trypanosoma Cruzi Parasitic Load in Women of Reproductive Age [Phase 3]
Phase 3 clinical trial evaluating a short-course benznidazole regimen to reduce Trypanosoma cruzi parasite load in women of reproductive age…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease. [Phase 2]
A Phase 2 clinical trial evaluating the efficacy, safety, and tolerability of LXE408 in adults with chronic Chagas disease, currently recrui…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease [NA]
A completed clinical trial evaluating sympathetic denervation by video-assisted thoracoscopy to control cardiac arrhythmias in patients with…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Prospective Evaluation of Rapid Diagnostic Tests for Trypanosoma Cruzi Infection
Prospective evaluation of rapid diagnostic tests for Trypanosoma cruzi infection in individuals with chronic Chagas disease; the study is cu…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC [Phase 4]
Phase 4 trial comparing sacubitril/valsartan to enalapril in patients with Chagas disease-related cardiomyopathy, assessing morbidity, morta…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: University-Based Chagas Testing in Salta Province, Argentina
An ongoing university-based Chagas disease testing study in Salta Province, Argentina is enrolling by invitation, sponsored by the Mundo San…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Delivering a Multi-disease Screening Tool to Migrant Populations [NA]
This update reports the completion of a trial evaluating a multi-disease screening tool for migrant populations. The study targeted HIV, hep…
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CLINICAL_TRIALS withdrawal · 2025-03-13Clinical Trial Update: Short Benznidazole Regimen for Chronic Phase Chagas Disease Patients [Phase 3]
A Phase 3 trial evaluating a shortened benznidazole regimen for chronic-phase Chagas disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Atorvastatin on Inflammation and Cardiac Function in Chronic Chagas Disease [Phase 2]
A Phase 2 clinical trial evaluating atorvastatin for inflammation and cardiac function in Chagas disease was terminated.
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: New Therapies and Biomarkers for Chagas Infection [Phase 2]
Phase 2 clinical trial update on new therapies and biomarkers for Chagas disease, with the study status shown as completed.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: SBRT in Chagas Disease Ventricular Tachycardia [Phase 1, Phase 2]
This clinical trial update notes a Phase 1/Phase 2 study evaluating stereotactic body radiotherapy for ventricular tachycardia in patients w…
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CLINICAL_TRIALS trial_result · 2023-12-19Clinical Trial Update: Evaluation of Different Benznidazole Regimens for the Treatment of Chronic Chagas Disease. [Phase 2]
A phase 2 trial evaluating different benznidazole regimens for chronic Chagas disease has completed.
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: Shorter Benznidazole Regimens Compared to the Standard Regimen for Chagas Disease [Phase 3]
Phase 3 trial investigating shorter benznidazole regimens versus standard regimen for Chagas disease; currently recruiting.
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FDA approval · 2023-06-02FDA Approved: LAMPIT — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
The FDA approved a supplemental application for Lampit (nifurtimox) from Bayer HealthCare Pharmaceuticals Inc., signaling an update to its l…
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FDA approval · 2023-02-22FDA Approved: LAMPIT — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA supplemental application for Lampit (nifurtimox) from Bayer HealthCare Pharmaceuticals Inc., seeking regulatory action on an updated ind…
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FDA approval · 2022-01-27FDA Approved: LAMPIT — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA approved a supplemental application for Lampit (nifurtimox) from Bayer HealthCare Pharmaceuticals Inc., expanding the drug's approved in…
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FDA label_change · 2021-12-15FDA Approved: BENZNIDAZOLE — Supplemental Application (Exeltis USA, Inc.)
FDA approved a supplemental application for benznidazole by Exeltis USA, Inc., indicating an approved update to the product labeling.
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Chagas Disease
Clinical trial update evaluating speckle tracking strain as a predictor of myocardial fibrosis in Chagas disease has completed with posted r…
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FDA approval · 2020-10-02FDA Approved: LAMPIT — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
The FDA approved a supplemental application for Lampit (nifurtimox) from Bayer HealthCare Pharmaceuticals Inc., supporting its regulatory ap…
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FDA approval · 2020-08-06FDA Approved: LAMPIT — Original Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA approves Lampit (nifurtimox) under an original application by Bayer for the treatment of Chagas disease.
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease [Phase 3]
Phase 3 trial evaluating benznidazole for chronic Chagas disease has completed.
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FDA approval · 2019-11-07FDA Approved: BENZNIDAZOLE — Supplemental Application (Exeltis USA, Inc.)
The FDA approved a supplemental application for benznidazole from Exeltis USA, Inc., updating the labeling for this product. This reflects a…
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: A Study to Learn How Well Nifurtimox Works and How Safe it is in Children Aged 0 to 17 Years With Chagas' Disease, an Inflammatory, Infectious Disease Caused by the Parasite Trypanosoma Cruzi [Phase 3]
Phase 3 trial evaluating nifurtimox in children with Chagas disease has completed and results were posted in 2019.