Chagas Disease
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: Colchicine for Patients With Chagas´ Disease( B1 Stage) [Phase 2]
Phase 2 clinical trial investigating colchicine for patients with Chagas disease and colchicine resistance.
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas Disease [Phase 4]
Phase 4 trial evaluating an optimized PCR method to assess parasitological response in chronic Chagas disease.
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: Population Pharmacokinetics Study of Benznidazole in Children With Chagas'Disease [Phase 4]
A Phase 4 population pharmacokinetics study of benznidazole in children with Chagas disease has completed.
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Lower Urinary Tract Dysfunction in Chronic Chagas' Disease : Clinical and Urodynamic Presentation
This update summarizes a completed clinical trial investigating lower urinary tract dysfunction in chronic Chagas disease, including clinica…
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CLINICAL_TRIALS trial_result · 2017-12-20Clinical Trial Update: BENDITA BEnznidazole New Doses Improved Treatment and Associations [Phase 2]
Phase 2 update on Bendita benznidazole new doses showing improved treatment and associations for Chagas disease.
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Galectin-3 as a Biomarker in Patients With Chagas Disease
A completed clinical trial investigating galectin-3 as a biomarker in patients with Chagas disease.
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FDA approval · 2017-08-29FDA Approved: BENZNIDAZOLE — Original Application (Exeltis USA, Inc.)
FDA approved the original application for benznidazole (Exeltis USA, Inc.) to treat Chagas disease.
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Specificity Study of Diagnostic for Chagas Disease
This clinical trial update reports the completion of a specificity study evaluating a diagnostic test for Chagas disease.
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CLINICAL_TRIALS trial_result · 2017-07-27Clinical Trial Update: Physical Exercise Program in Chronic Chagas Heart Disease [Phase 3]
Phase 3 clinical trial evaluating a physical exercise program for chronic Chagas heart disease has completed. Sponsor: Evandro Chagas Nation…
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CLINICAL_TRIALS research · 2017-07-21Clinical Trial Update: CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY) [Phase 2, Phase 3]
A Phase 2/3 trial (EQUITY) evaluating equivalence of usual interventions for Chagas disease; current status is unknown.
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CLINICAL_TRIALS trial_result · 2016-11-16Clinical Trial Update: Congenital Transmission of Lineages I and II of Trypanosoma Cruzi
This clinical trial update reports on congenital transmission of Trypanosoma cruzi lineages I and II in Chagas disease, with the study statu…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Study to Assess the Food Effect on the Pharmacokinetics of Nifurtimox Tablets in Chronic Chagas' Patients [Phase 1]
Phase 1 study assessed the effect of food on nifurtimox pharmacokinetics in chronic Chagas disease; the study has completed.
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas Disease [Phase 4]
Phase 4 study evaluating the Medtronic Reveal LINQ Insertable Cardiac Monitor in patients with Chagas disease has been terminated.
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CLINICAL_TRIALS research · 2016-08-22Clinical Trial Update: New Tools for the Diagnosis, Prognosis and Treatment Follow-up in Chagas Disease
A completed clinical trial evaluating new tools for diagnosis, prognosis, and treatment follow-up in Chagas disease.
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CLINICAL_TRIALS trial_result · 2016-07-15Clinical Trial Update: Chagas Disease as an Undiagnosed Type of Cardiomyopathy in the United States
The NHLBI-sponsored trial evaluated Chagas disease as an undiagnosed form of cardiomyopathy in the United States and has completed.
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Genetic Architecture of Heart Disease in Rural Brazil
This NHLBI-sponsored, completed trial investigated the genetic architecture of heart disease in rural Brazil, including participants with Ch…
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CLINICAL_TRIALS research · 2016-01-21Clinical Trial Update: Impact of the Pharmaceutical Care on the Quality of Life in Patients With Chagas Heart Disease [NA]
Clinical trial update assessing the impact of pharmaceutical care on the quality of life in patients with Chagas heart disease. Status is li…
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CLINICAL_TRIALS trial_result · 2016-01-06Clinical Trial Update: Longitudinal Study of Patients With Chronic Chagas Cardiomyopathy in Brazil (SaMi_Trop Project)
Completed longitudinal study of patients with chronic Chagas cardiomyopathy in Brazil (SaMi_Trop Project) sponsored by the University of Sao…
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: Sensitivity Study of Diagnostic for Detection of Chagas Infection
This completed clinical trial from InBios International assesses the sensitivity of a diagnostic test for detecting Chagas infection.
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CLINICAL_TRIALS trial_result · 2015-11-10Clinical Trial Update: Selenium Treatment and Chagasic Cardiopathy (STCC) [Phase 3]
This entry notes an ongoing Phase 3 clinical trial evaluating selenium treatment for Chagasic cardiopathy.
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CLINICAL_TRIALS trial_result · 2015-10-16Clinical Trial Update: Study to Assess Bioequivalence of 30 and 120 mg Nifurtimox Tablets in Chronic Chagas' Patients [Phase 1]
A Phase 1 trial assessing the bioequivalence of 30 mg and 120 mg nifurtimox tablets in chronic Chagas disease patients; the study has comple…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Syndecan-4 as a Biomarker in Patients With Chagas Disease
A completed clinical trial evaluating Syndecan-4 as a biomarker in patients with Chagas disease.
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CLINICAL_TRIALS research · 2015-10-12Clinical Trial Update: Determination of Genetic Polymorphisms in Chronic Chagas Cardiomyopathy
A completed clinical trial investigating genetic polymorphisms associated with chronic Chagas cardiomyopathy.
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Exercise Training in Chagas Cardiomyopathy [Phase 4]
A Phase 4 clinical trial evaluating exercise training in patients with Chagas disease–related cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: A Randomized Trial of Carvedilol in Chronic Chagas Cardiomyopathy [Phase 4]
A Phase 4 randomized trial evaluating carvedilol in chronic Chagas cardiomyopathy has completed.