Chagas Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Short-course Benznidazole Treatment to Reduce Trypanosoma Cruzi Parasitic Load in Women of Reproductive Age [Phase 3]
Phase 3 clinical trial evaluating a short-course benznidazole regimen to reduce Trypanosoma cruzi parasite load in women of reproductive age…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease [NA]
A completed clinical trial evaluating sympathetic denervation by video-assisted thoracoscopy to control cardiac arrhythmias in patients with…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC [Phase 4]
Phase 4 trial comparing sacubitril/valsartan to enalapril in patients with Chagas disease-related cardiomyopathy, assessing morbidity, morta…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Delivering a Multi-disease Screening Tool to Migrant Populations [NA]
This update reports the completion of a trial evaluating a multi-disease screening tool for migrant populations. The study targeted HIV, hep…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Atorvastatin on Inflammation and Cardiac Function in Chronic Chagas Disease [Phase 2]
A Phase 2 clinical trial evaluating atorvastatin for inflammation and cardiac function in Chagas disease was terminated.
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: New Therapies and Biomarkers for Chagas Infection [Phase 2]
Phase 2 clinical trial update on new therapies and biomarkers for Chagas disease, with the study status shown as completed.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: SBRT in Chagas Disease Ventricular Tachycardia [Phase 1, Phase 2]
This clinical trial update notes a Phase 1/Phase 2 study evaluating stereotactic body radiotherapy for ventricular tachycardia in patients w…
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CLINICAL_TRIALS trial_result · 2023-12-19Clinical Trial Update: Evaluation of Different Benznidazole Regimens for the Treatment of Chronic Chagas Disease. [Phase 2]
A phase 2 trial evaluating different benznidazole regimens for chronic Chagas disease has completed.
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: Shorter Benznidazole Regimens Compared to the Standard Regimen for Chagas Disease [Phase 3]
Phase 3 trial investigating shorter benznidazole regimens versus standard regimen for Chagas disease; currently recruiting.
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Chagas Disease
Clinical trial update evaluating speckle tracking strain as a predictor of myocardial fibrosis in Chagas disease has completed with posted r…
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease [Phase 3]
Phase 3 trial evaluating benznidazole for chronic Chagas disease has completed.
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: A Study to Learn How Well Nifurtimox Works and How Safe it is in Children Aged 0 to 17 Years With Chagas' Disease, an Inflammatory, Infectious Disease Caused by the Parasite Trypanosoma Cruzi [Phase 3]
Phase 3 trial evaluating nifurtimox in children with Chagas disease has completed and results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: Colchicine for Patients With Chagas´ Disease( B1 Stage) [Phase 2]
Phase 2 clinical trial investigating colchicine for patients with Chagas disease and colchicine resistance.
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas Disease [Phase 4]
Phase 4 trial evaluating an optimized PCR method to assess parasitological response in chronic Chagas disease.
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: Population Pharmacokinetics Study of Benznidazole in Children With Chagas'Disease [Phase 4]
A Phase 4 population pharmacokinetics study of benznidazole in children with Chagas disease has completed.
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Lower Urinary Tract Dysfunction in Chronic Chagas' Disease : Clinical and Urodynamic Presentation
This update summarizes a completed clinical trial investigating lower urinary tract dysfunction in chronic Chagas disease, including clinica…
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CLINICAL_TRIALS trial_result · 2017-12-20Clinical Trial Update: BENDITA BEnznidazole New Doses Improved Treatment and Associations [Phase 2]
Phase 2 update on Bendita benznidazole new doses showing improved treatment and associations for Chagas disease.
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Galectin-3 as a Biomarker in Patients With Chagas Disease
A completed clinical trial investigating galectin-3 as a biomarker in patients with Chagas disease.
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Specificity Study of Diagnostic for Chagas Disease
This clinical trial update reports the completion of a specificity study evaluating a diagnostic test for Chagas disease.
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CLINICAL_TRIALS trial_result · 2017-07-27Clinical Trial Update: Physical Exercise Program in Chronic Chagas Heart Disease [Phase 3]
Phase 3 clinical trial evaluating a physical exercise program for chronic Chagas heart disease has completed. Sponsor: Evandro Chagas Nation…
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CLINICAL_TRIALS trial_result · 2016-11-16Clinical Trial Update: Congenital Transmission of Lineages I and II of Trypanosoma Cruzi
This clinical trial update reports on congenital transmission of Trypanosoma cruzi lineages I and II in Chagas disease, with the study statu…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Study to Assess the Food Effect on the Pharmacokinetics of Nifurtimox Tablets in Chronic Chagas' Patients [Phase 1]
Phase 1 study assessed the effect of food on nifurtimox pharmacokinetics in chronic Chagas disease; the study has completed.
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas Disease [Phase 4]
Phase 4 study evaluating the Medtronic Reveal LINQ Insertable Cardiac Monitor in patients with Chagas disease has been terminated.
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CLINICAL_TRIALS trial_result · 2016-07-15Clinical Trial Update: Chagas Disease as an Undiagnosed Type of Cardiomyopathy in the United States
The NHLBI-sponsored trial evaluated Chagas disease as an undiagnosed form of cardiomyopathy in the United States and has completed.
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Genetic Architecture of Heart Disease in Rural Brazil
This NHLBI-sponsored, completed trial investigated the genetic architecture of heart disease in rural Brazil, including participants with Ch…