Central Nervous System Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-08-08Clinical Trial Update: Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors [Phase 1]
Phase 1 study evaluating irinotecan and bevacizumab with temozolomide in refractory/relapsed CNS tumors; trial completed with results posted…
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CLINICAL_TRIALS trial_result · 2019-04-25Clinical Trial Update: Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma [Phase 2]
Phase 2 trial evaluating low-dose radiation plus combination chemotherapy after surgery in children with newly diagnosed medulloblastoma; st…
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CLINICAL_TRIALS trial_result · 2019-02-28Clinical Trial Update: Bevacizumab in Recurrent Grade II and III Glioma [Phase 2]
Phase 2 clinical trial update evaluating bevacizumab for recurrent grade II and III glioma has been completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas [Phase 1]
This Phase I trial evaluated the combination of vorinostat and bortezomib in pediatric patients with refractory or recurrent solid tumors, i…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: High-dose ICE With Amifostine [Phase 2]
Phase 2 trial evaluating high-dose ICE chemotherapy with Amifostine has completed accrual and results are reported for multiple solid tumors…
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CLINICAL_TRIALS trial_result · 2016-07-13Clinical Trial Update: Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma [Phase 2]
Phase 2 clinical trial investigating chemotherapy followed by radiation therapy for adults with supratentorial glioma has completed.
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Gene Expression and Location in Samples From Patients With Brain Tumors
This completed clinical trial studied gene expression and the spatial distribution of genes in samples from patients with brain tumors.
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Study of Peptide Vaccination With Tumor Associated Antigens Mixed With Montanide in Patients With CNS Tumors [Phase 1]
Phase 1 trial evaluating a peptide vaccine with tumor-associated antigens given with Montanide adjuvant in patients with central nervous sys…
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors [Phase 2]
Arsenic trioxide was studied in a Phase 2 trial for children with advanced neuroblastoma and other childhood solid tumors; results have been…
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CLINICAL_TRIALS trial_result · 2015-05-04Clinical Trial Update: PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors [Phase 1]
A Phase 1 study of PTC299 in pediatric patients with refractory or recurrent primary central nervous system tumors has completed. The trial …
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CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors [Phase 1]
Phase 1 clinical trial evaluating valproic acid in children with recurrent or refractory solid tumors or central nervous system tumors; the …
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain Tumors
This update notes the completion of a clinical trial evaluating gene testing to aid diagnosis and treatment of childhood brain tumors. No tr…
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma [Phase 1]
Phase 1 trial evaluating combination chemotherapy plus radiation therapy for newly diagnosed brain stem glioma has completed.
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CLINICAL_TRIALS trial_result · 2014-03-28Clinical Trial Update: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors [Phase 1]
A Phase 1 clinical trial evaluates chemotherapy plus peripheral stem cell transplantation in infants with malignant brain or spinal cord tum…
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors [Phase 2]
Phase 2 trial evaluating neoadjuvant chemotherapy with or without second-look surgery followed by radiation with or without peripheral stem …
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme [Phase 2]
Phase 2 trial of radiation therapy followed by bleomycin in adults with newly diagnosed supratentorial glioblastoma multiforme (brain tumor)…
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment [Phase 2]
Phase 2 trial evaluating cyproheptadine and megestrol to prevent weight loss in children with cancer-related cachexia; the study has complet…
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CLINICAL_TRIALS trial_result · 2013-12-19Clinical Trial Update: Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial assessing Calcitriol plus Carboplatin in adults with advanced solid tumors, including brain/CNS tumors; the study has…
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CLINICAL_TRIALS research · 2013-12-18Clinical Trial Update: Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors [Phase 3]
Phase 3 trial assessing chemotherapy with or without etoposide followed by autologous stem cell transplant in young patients with previously…
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CLINICAL_TRIALS research · 2013-09-20Clinical Trial Update: Thiotepa and Radiation Therapy in Treating Young Patients With Newly Diagnosed Malignant Brain Tumors [Phase 2]
Phase 2 clinical trial evaluating thiotepa combined with radiation therapy for newly diagnosed malignant brain tumors in young patients.
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CLINICAL_TRIALS trial_result · 2013-09-19Clinical Trial Update: Methylphenidate HCl or Modafinil in Treating Young Patients With Excessive Daytime Sleepiness After Cancer Therapy [Phase 2]
A Phase 2 clinical trial evaluated methylphenidate HCl or modafinil for excessive daytime sleepiness in young patients after cancer therapy.…
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CLINICAL_TRIALS trial_result · 2013-09-09Clinical Trial Update: Combination Chemotherapy in Treating Children With Progressive Brain Tumors [Phase 3]
The document reports the completion of a Phase 3 clinical trial evaluating combination chemotherapy for pediatric progressive brain tumors.
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CLINICAL_TRIALS trial_result · 2013-08-16Clinical Trial Update: Lobradimil and Carboplatin in Treating Children With Brain Tumors [Phase 2]
A Phase 2 clinical trial evaluating the combination of lobradimil and carboplatin for children with brain or central nervous system tumors h…
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CLINICAL_TRIALS trial_result · 2013-07-18Clinical Trial Update: Gallium Nitrate in Treating Children With Brain Tumor, Neuroblastoma, Rhabdomyosarcoma, Non-Hodgkin's Lymphoma, or Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating gallium nitrate in pediatric patients with brain tumors, neuroblastoma, rhabdomyosarcoma, non-Hodgkin's lymphoma, o…
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors [Phase 2]
Phase 2 trial update evaluating the combination of chemotherapy and tamoxifen in patients with solid tumors has completed.