Central Nervous System Tumors
📧 Sign up to get email alerts when something new happens for Central Nervous System Tumors.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors [Phase 2]
A Phase 2 trial evaluating Entrectinib as a single-agent upfront therapy for children under 3 with NTRK1/2/3 or ROS1-fused CNS tumors is cur…
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of PHST001 in Advanced Solid Tumors [Phase 1]
Pheast Therapeutics is recruiting for a Phase 1 study of PHST001 in patients with advanced solid tumors, including ovarian cancer, endometri…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Mirdametinib in People With Central Nervous System Tumors [Phase 1, Phase 2]
This document provides an update on an ongoing Phase 1/Phase 2 clinical trial evaluating Mirdametinib in people with central nervous system …
-
CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials [NA]
A clinical trial update describing efforts to improve adolescent and young adult self-reported data in ECOG-ACRIN trials, with trials curren…
-
CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors [NA]
Observational study in recurrent central nervous system tumors to evaluate responses to various treatments in brain tumors, with ongoing rec…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options [Phase 1, Phase 2]
Ongoing pediatric study of entrectinib (Rxdx-101) for locally advanced or metastatic solid tumors and/or primary CNS tumors with no satisfac…
-
CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors [Phase 2]
A Phase 2 clinical trial investigates sirolimus in combination with metronomic chemotherapy in children with recurrent or refractory solid t…
-
CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Intraoperative Use of I.V. Sodium Fluorescein in Suspected CNS Tumors
This clinical trial updates the use of intravenous sodium fluorescein during surgery for suspected central nervous system tumors and is curr…
-
CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors [Phase 1]
A phase 1 trial evaluating the safety of combining avelumab with lenvatinib in children with central nervous system tumors; the study is act…
-
CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional HER2-targeted CAR T-cell therapy for pediatric recurrent or refractory central nervous system tumors a…
-
CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors. [Phase 4]
A Phase 4 clinical trial evaluating the use of the radiotracer 68-Gallium DOTATATE PET/MRI for diagnosing and managing somatostatin receptor…
-
CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients
St. Jude Children's Research Hospital is conducting a prospective study to perform next-generation sequencing on normal tissues in pediatric…
-
CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: OH2 Oncolytic Viral Therapy in Central Nervous System Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial of OH2 Oncolytic Viral Therapy for central nervous system tumors is currently recruiting.
-
CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Computer-based Neurocognitive Assessment in Children With Central Nervous System Tumors Receiving Proton Beam Radiation Therapy
This clinical trial update indicates a study evaluating computer-based neurocognitive assessment in children with central nervous system tum…
-
CLINICAL_TRIALS research · 2013-12-18Clinical Trial Update: Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors [Phase 3]
Phase 3 trial assessing chemotherapy with or without etoposide followed by autologous stem cell transplant in young patients with previously…
-
CLINICAL_TRIALS research · 2013-09-20Clinical Trial Update: Thiotepa and Radiation Therapy in Treating Young Patients With Newly Diagnosed Malignant Brain Tumors [Phase 2]
Phase 2 clinical trial evaluating thiotepa combined with radiation therapy for newly diagnosed malignant brain tumors in young patients.
-
CLINICAL_TRIALS research · 2008-02-06Clinical Trial Update: Administration of High Dose Thiotepa and Melphalan With Autologous Hematopoietic Stem Cell Transplant in Children and Adolescents With Solid Tumors [NA]
Clinical trial update on administering high-dose thiotepa and melphalan with autologous hematopoietic stem cell transplant in children and a…