Central Nervous System Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: POWER UP: Participating Online While Exercising to Recover Using Play [NA]
A clinical trial called POWER UP studying online participation during exercise to help recovery for central nervous system tumors has been t…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: A Nomogram for Predicting the Diagnosis of Central Malignant Tumors Based on Preoperative Clinical Characteristics and Laboratory Indicators:
A completed clinical trial evaluates a nomogram based on preoperative clinical characteristics and laboratory indicators to predict diagnose…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors [Phase 2]
Phase 2 trial update of haploidentical transplantation with donor natural killer cells for solid tumors; the study was terminated and result…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Feasibility of Using Bortezomib With or Without Chemotherapy in Patients With Atypical Teratoid/Rhabdoid Tumors [Phase 2]
Phase 2 trial update evaluating the feasibility of adding bortezomib, with or without standard chemotherapy, in patients with atypical terat…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma [Phase 1, Phase 2]
Regeneron’s cemiplimab (REGN2810) was studied in pediatric patients with relapsed/refractory solid tumors and CNS tumors, including a safety…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: A Study of TAS-120 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of futibatinib (TAS-120) in patients with advanced solid tumors, including cholangiocarcinoma, urothelial carcinoma, breas…
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CLINICAL_TRIALS trial_result · 2023-08-30Clinical Trial Update: Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors [Phase 1, Phase 2]
A Phase 1/2 study evaluating lenvatinib in combination with everolimus for pediatric patients with recurrent and refractory solid tumors, in…
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CLINICAL_TRIALS trial_result · 2023-03-30Clinical Trial Update: Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors [Phase 1]
Phase 1 pediatric trial evaluating a triple combination of nanoparticle albumin-bound rapamycin, temozolomide, and irinotecan for recurrent …
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CLINICAL_TRIALS trial_result · 2021-10-27Clinical Trial Update: Indocyanine Green for Central Nervous System Tumors [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating indocyanine green for suspected central nervous system tumors; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-08-13Clinical Trial Update: Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor [Phase 2]
A Phase 2 trial evaluated modafinil for memory and attention problems in children after cancer treatment for brain tumors; results have been…
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CLINICAL_TRIALS trial_result · 2021-04-05Clinical Trial Update: Study of Lenalidomide With Vorinostat in Pediatric Patients With High Grade or Progressive CNS Tumors [Phase 1]
Phase 1 trial evaluating lenalidomide with vorinostat in pediatric high-grade or progressive CNS tumors; study terminated with results poste…
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CLINICAL_TRIALS trial_result · 2019-08-08Clinical Trial Update: Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors [Phase 1]
Phase 1 study evaluating irinotecan and bevacizumab with temozolomide in refractory/relapsed CNS tumors; trial completed with results posted…
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CLINICAL_TRIALS trial_result · 2019-04-25Clinical Trial Update: Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma [Phase 2]
Phase 2 trial evaluating low-dose radiation plus combination chemotherapy after surgery in children with newly diagnosed medulloblastoma; st…
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CLINICAL_TRIALS trial_result · 2019-02-28Clinical Trial Update: Bevacizumab in Recurrent Grade II and III Glioma [Phase 2]
Phase 2 clinical trial update evaluating bevacizumab for recurrent grade II and III glioma has been completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas [Phase 1]
This Phase I trial evaluated the combination of vorinostat and bortezomib in pediatric patients with refractory or recurrent solid tumors, i…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: High-dose ICE With Amifostine [Phase 2]
Phase 2 trial evaluating high-dose ICE chemotherapy with Amifostine has completed accrual and results are reported for multiple solid tumors…
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CLINICAL_TRIALS trial_result · 2016-07-13Clinical Trial Update: Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma [Phase 2]
Phase 2 clinical trial investigating chemotherapy followed by radiation therapy for adults with supratentorial glioma has completed.
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Gene Expression and Location in Samples From Patients With Brain Tumors
This completed clinical trial studied gene expression and the spatial distribution of genes in samples from patients with brain tumors.
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Study of Peptide Vaccination With Tumor Associated Antigens Mixed With Montanide in Patients With CNS Tumors [Phase 1]
Phase 1 trial evaluating a peptide vaccine with tumor-associated antigens given with Montanide adjuvant in patients with central nervous sys…
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors [Phase 2]
Arsenic trioxide was studied in a Phase 2 trial for children with advanced neuroblastoma and other childhood solid tumors; results have been…
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CLINICAL_TRIALS trial_result · 2015-05-04Clinical Trial Update: PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors [Phase 1]
A Phase 1 study of PTC299 in pediatric patients with refractory or recurrent primary central nervous system tumors has completed. The trial …
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CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors [Phase 1]
Phase 1 clinical trial evaluating valproic acid in children with recurrent or refractory solid tumors or central nervous system tumors; the …
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain Tumors
This update notes the completion of a clinical trial evaluating gene testing to aid diagnosis and treatment of childhood brain tumors. No tr…
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma [Phase 1]
Phase 1 trial evaluating combination chemotherapy plus radiation therapy for newly diagnosed brain stem glioma has completed.
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CLINICAL_TRIALS trial_result · 2014-03-28Clinical Trial Update: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors [Phase 1]
A Phase 1 clinical trial evaluates chemotherapy plus peripheral stem cell transplantation in infants with malignant brain or spinal cord tum…