B-cell Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-22Clinical Trial Update: Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma [Phase 2]
Phase 2 trial evaluating rituximab in patients undergoing donor peripheral blood stem cell transplantation for relapsed or refractory B-cell…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Biomarkers in Samples From Patients With B-Cell Acute Lymphoblastic Leukemia
The update summarizes biomarker analyses performed on samples from patients with B-cell acute lymphoblastic leukemia. The study status is co…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 trial updated on dosing of vincristine (low-dose vs high-dose) plus combination chemotherapy for relapsed B-cell acute lymphoblast…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update evaluating whether adding donor stem cell transplantation to combination chemotherapy improves outcomes in adu…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Genetically Modified Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 trial evaluating genetically modified haploidentical natural killer cell infusions for B-lineage acute lymphoblastic leukemia has co…
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CLINICAL_TRIALS withdrawal · 2017-04-10Clinical Trial Update: A Study to Determine Safety, Feasibility and Efficacy of JCAR015 in Adult Subjects With B-Cell Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A clinical trial evaluating JCAR015 in adults with B-cell acute lymphoblastic leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy [Phase 1]
Phase 1 trial evaluating CART19 therapy for B-cell hematologic malignancies including various lymphomas and leukemias that are refractory or…
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CLINICAL_TRIALS withdrawal · 2017-02-14Clinical Trial Update: Study of Efficacy and Safety of CTL019 in Adult ALL Patients [Phase 2]
A Phase 2 study examining CTL019 (tisagenlecleucel) in adults with B-cell acute lymphoblastic leukemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-01-27Clinical Trial Update: Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 dose-escalation study in relapsed or refractory acute myeloid leukemia and relapsed/refractory B-cell acute lymphoblastic leukemia…
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CLINICAL_TRIALS withdrawal · 2017-01-19Clinical Trial Update: Testing a Reduced Conditioning Regimen FB2A2 Preceded by a Fractionated Radio-immunotherapy (RIT) With 90Y-Epratuzumab Before Allogeneic Stem Cell Transplantation for Patients With Lymphocyte B CD22 Positive Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
This clinical trial update reports withdrawal of a Phase 1/2 study evaluating a reduced conditioning regimen with 90Y-epratuzumab radioimmun…
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CLINICAL_TRIALS withdrawal · 2017-01-19Clinical Trial Update: Study Evaluating the Efficacy of 90Yttrium-epratuzumab in Adults With CD22+ Relapsed/Refractory B-ALL [Phase 2]
A Phase 2 study evaluating 90Yttrium-epratuzumab for CD22-positive relapsed/refractory B-cell acute lymphoblastic leukemia in adults has bee…
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CLINICAL_TRIALS trial_result · 2017-01-16Clinical Trial Update: Ibrutinib in Treating Patients With Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia [Phase 2]
This clinical trial update reports the termination of a Phase 2 study of ibrutinib in adults with relapsed or refractory B-cell acute lympho…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: A Phase I Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell Leukemia [Phase 1]
Update on a Phase I trial of 4SCAR19 cells for relapsed/refractory B-cell acute lymphoblastic leukemia. The trial status is currently UNKNOW…
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CLINICAL_TRIALS research · 2016-06-09Clinical Trial Update: CD22 Targeting CAR-T Therapy Against B Cell Hematological Malignancies [Phase 1, Phase 2]
This entry reports a phase 1/2 clinical trial of a CD22-targeted CAR-T therapy for recurrent or refractory B-cell malignancies; the status i…
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Study of mAb 216 With Chemotherapy for Treatment of Pediatric Relapsed or Refractory B-progenitor Acute Lymphoblastic Leukemia [Phase 1]
This notice reports the termination of a Phase 1 clinical trial studying monoclonal antibody 216 in combination with chemotherapy for childr…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic Leukemia
This completed clinical trial from the Children's Oncology Group studied biomarkers as a diagnostic tool in samples from younger patients wi…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia
Completed clinical trial update studying gene analyses in samples from younger patients with relapsed childhood acute lymphoblastic leukemia…
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Response or Resistance to Chemotherapy in Young Patients With Acute Lymphoblastic Leukemia Treated With Methotrexate
This clinical trial update summarizes how young patients with acute lymphoblastic leukemia responded to or developed resistance to methotrex…
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CLINICAL_TRIALS research · 2016-02-03Clinical Trial Update: A Study to Assess CD19-targeted Immunotherapy T Cells in Patients With Relapsed or Refractory CD19+ B Cell Leukemia [Phase 1, Phase 2]
A clinical trial update describing a Phase 1/2 study evaluating CD19-targeted immunotherapy T cells in patients with relapsed or refractory …
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CLINICAL_TRIALS withdrawal · 2015-10-30Clinical Trial Update: Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 study evaluating Nilotinib with combination chemotherapy for newly diagnosed Philadelphia chromosome-positive acute lymphoblastic …
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma [Phase 1]
This Phase 1 study evaluated a multi-drug regimen of temsirolimus, dexamethasone, mitoxantrone, vincristine, and pegaspargase in pediatric p…
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CLINICAL_TRIALS trial_result · 2015-02-12Clinical Trial Update: Confirmatory Phase II Study of Blinatumomab (MT103) in Patients With Minimal Residual Disease of B-precursor Acute Lymphoblastic Leukemia (ALL) [Phase 2]
A confirmatory Phase II study evaluating blinatumomab (MT103) in patients with minimal residual disease in B-cell acute lymphoblastic leukem…
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: Study of the BiTE® Blinatumomab (MT103) in Adult Patients With Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 study evaluating blinatumomab in adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (B-ALL).
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CLINICAL_TRIALS trial_result · 2014-09-16Clinical Trial Update: Chemotherapy Plus Rituximab Combination for Adult Lymphoblastic Leukemia (B-ALL) and Burkitt's Non-Hodgkin Lymphoma [Phase 2]
Phase 2 trial evaluating chemotherapy plus rituximab for adults with Burkitt lymphoma or B-cell acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS research · 2014-07-14Clinical Trial Update: Monoclonal Antibodies in Recurrent or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL) (MARALL) [Phase 1, Phase 2]
This entry outlines a Phase 1/2 clinical trial (MARALL) evaluating monoclonal antibodies for recurrent or refractory B-cell acute lymphoblas…