Clinical Trial Update: Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma [Phase 1]

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Summary

This Phase 1 study evaluated a multi-drug regimen of temsirolimus, dexamethasone, mitoxantrone, vincristine, and pegaspargase in pediatric patients with relapse…

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Diseases / indications

• B-cell Acute Lymphoblastic Leukemia
• Lymphoblastic Lymphoma
• Mature T-cell Non-hodgkin Lymphoma
• Natural Killer Cell Non-hodgkin Lymphoma
• T-cell Acute Lymphoblastic Leukemia

Drugs mentioned

• Decadron (Dexamethasone)
• Novantrone (mitoxantrone)
• Oncaspar (pegaspargase)
• Oncovin (vincristine)
• Torisel (Temsirolimus)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Childhood B Acute Lymphoblastic Leukemia, Childhood T Acute Lymphoblastic Leukemia | Phase 1 | Status: COMPLETED