B-cell Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL) [Phase 2]
Phase 2 clinical trial update for KTE-X19 in minimal residual disease–positive B-cell acute lymphoblastic leukemia, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Autologous CD22 CAR T Cells in Adults w/ Recurrent or Refractory B Cell Malignancies [Phase 1]
Phase 1 trial evaluating autologous CD22 CAR T cells in adults with recurrent or refractory B-cell malignancies has completed enrollment. Re…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML) [Phase 1]
Phase 1 clinical trial of CD123-directed T-cell therapy for acute myeloid leukemia and related hematologic diseases is currently recruiting …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19) [Phase 1, Phase 2]
A Phase 1/2 clinical trial of SENTRY-CD19, a CD19-targeted gene therapy, in multiple CD19-positive hematologic malignancies is currently rec…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: NexCAR19 (Talikabtagene Autoleucel) in Relapsed/Refractory B-Cell Malignancies (NexCAR19) [Phase 2, Phase 3]
Clinical trial update for NexCAR19 (Talikabtagene autoleucel), a CAR-T therapy studied in relapsed/refractory B-cell malignancies; the Phase…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 clinical trial evaluating different fludarabine dosing regimens in children and young adults with B-cell acute lymphoblastic leuke…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Co-administration of CART22-65s and huCART19 for B-ALL [Phase 1, Phase 2]
This document reports a Phase 1/2 clinical trial update on co-administering CART22-65s and huCART19 for B-cell acute lymphoblastic leukemia …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Immunotherapy Combined With Auto-HSCT and CD22/CD19 CAR-T Sandwich Strategy for B-ALL [Phase 2]
Phase 2 clinical trial evaluating a combination of immunotherapy with autologous hematopoietic stem cell transplant and CD22/CD19 CAR-T cell…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Clinical Study of Universal CD19 CAR-γδ T Cell Infusion in the Treatment of Relapsed/Refractory Acute B Lymphoblastic Leukemia [Phase 1]
Phase 1 clinical study evaluating universal CD19 CAR-γδ T cell infusion for relapsed/refractory acute lymphoblastic leukemia (B-cell lineage…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Study of Obecabtagene Autoleucel in People With B-cell Acute Lymphoblastic Leukemia [Phase 2]
This document announces a Phase 2 clinical trial evaluating Obecabtagene Autoleucel for B-cell acute lymphoblastic leukemia, with recruitmen…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies [Phase 1]
Phase 1 study evaluating PIT565 in relapsed/refractory B-cell malignancies, including B-cell Non-Hodgkin Lymphoma and B-cell Acute Lymphobla…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020) [Phase 3]
A Phase 3 international trial investigating treatment for childhood relapsed precursor B-cell acute lymphoblastic leukemia, with status not …
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Clinical Study Exploring the Safety, Efficacy and Cell Metabolic Kinetics of Universal Car-t Cell Injection in CD19 and / or CD20 Positive Relapsed / Refractory B-cell Acute Lymphoblastic Leukemia in Adolescents, Children and Adults [EARLY_Phase 1]
A Phase 1 clinical trial evaluating safety, efficacy, and cell metabolic kinetics of universal CAR-T cell therapy targeting CD19 and/or CD20…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CD19/CD22 bicistronic CAR T cells in children and young adults with recurrent or refractory CD19/CD…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1 [Phase 1]
This clinical trial update describes a Phase 1 study of UCD19 CAR T therapy in adults with B-cell acute lymphoblastic leukemia who are MRD-p…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Clinical Trial of CD19 and CD22 CAR Sequential Therapy Versus Single CD19 CAR Bridging to HSCT for r/r B-ALL Patients [NA]
A recruiting clinical trial is evaluating sequential CD19 and CD22 CAR-T cell therapy versus a single CD19 CAR bridging to hematopoietic ste…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial [Phase 1]
A Phase 1 clinical trial assessing donor-derived CD19 CAR T therapy bridging allogeneic HSCT, followed by donor-derived CD22 CAR T therapy, …
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Orphan Indications for CD19 Redirected Autologous T Cells [Phase 2]
Phase 2 trial update describing expanding orphan indications for CD19-directed autologous CAR-T therapy in pediatric and young adult B-cell …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 clinical trial of Venetoclax combined with a pediatric-inspired regimen for newly diagnosed B-cell acute lymphoblastic leukemia is c…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial is investigating the addition of asciminib to standard treatment for adults with newly diagnosed Philadelphia chrom…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Clinical Trial of CMD63 Chimeric Antigen Receptor T-cell (CAR T-cell) in Children With Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 clinical trial evaluating CMD63 CAR T-cell therapy in children with relapsed or refractory B-cell acute lymphoblastic leukemia, curr…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL) [Phase 1]
Phase 1 trial update for a CD19-targeted CAR T cell therapy in pediatric patients with relapsed or refractory B cell acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Expanded Access Program for OOS Obe-cel
Autolus Limited announced an Expanded Access Program for Obe-cel, its CAR-T therapy, to treat adults with acute lymphoblastic leukemia, incl…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of venetoclax and vincristine in adults with relapsed or refractory B- or T-cell acute lymphoblas…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab
A multi-site clinical trial is evaluating how long protective immunity from routine childhood vaccines lasts in participants with B-cell acu…