Clinical Trial Update: Orphan Indications for CD19 Redirected Autologous T Cells [Phase 2]

View source ↗

Summary

Phase 2 trial update describing expanding orphan indications for CD19-directed autologous CAR-T therapy in pediatric and young adult B-cell acute lymphoblastic …

Upgrade for the full analysis, importance score, and drug timeline.

Diseases / indications

• B-cell Acute Lymphoblastic Leukemia
• B-cell Acute Lymphoblastic Leukemia with Cns Relapse
• B-cell Acute Lymphoblastic Leukemia with Translocation
• Hypodiploid B-cell Acute Lymphoblastic Leukemia
• Kmt2a-rearranged B-cell Acute Lymphoblastic Leukemia

Drugs mentioned

• Kymriah (tisagenlecleucel)

Snippet

Sponsor: Stephan Grupp MD PhD | Conditions: Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL, Infants With Very High Risk KMT2A B-ALL | Phase 2 | Status: RECRUITING