B-cell Acute Lymphoblastic Leukemia
📧 Sign up to get email alerts when something new happens for B-cell Acute Lymphoblastic Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Study of Obecabtagene Autoleucel in People With B-cell Acute Lymphoblastic Leukemia [Phase 2]
This document announces a Phase 2 clinical trial evaluating Obecabtagene Autoleucel for B-cell acute lymphoblastic leukemia, with recruitmen…
-
CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies [Phase 1]
Phase 1 study evaluating PIT565 in relapsed/refractory B-cell malignancies, including B-cell Non-Hodgkin Lymphoma and B-cell Acute Lymphobla…
-
CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020) [Phase 3]
A Phase 3 international trial investigating treatment for childhood relapsed precursor B-cell acute lymphoblastic leukemia, with status not …
-
CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Clinical Study Exploring the Safety, Efficacy and Cell Metabolic Kinetics of Universal Car-t Cell Injection in CD19 and / or CD20 Positive Relapsed / Refractory B-cell Acute Lymphoblastic Leukemia in Adolescents, Children and Adults [EARLY_Phase 1]
A Phase 1 clinical trial evaluating safety, efficacy, and cell metabolic kinetics of universal CAR-T cell therapy targeting CD19 and/or CD20…
-
CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CD19/CD22 bicistronic CAR T cells in children and young adults with recurrent or refractory CD19/CD…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1 [Phase 1]
This clinical trial update describes a Phase 1 study of UCD19 CAR T therapy in adults with B-cell acute lymphoblastic leukemia who are MRD-p…
-
CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Clinical Trial of CD19 and CD22 CAR Sequential Therapy Versus Single CD19 CAR Bridging to HSCT for r/r B-ALL Patients [NA]
A recruiting clinical trial is evaluating sequential CD19 and CD22 CAR-T cell therapy versus a single CD19 CAR bridging to hematopoietic ste…
-
CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Orphan Indications for CD19 Redirected Autologous T Cells [Phase 2]
Phase 2 trial update describing expanding orphan indications for CD19-directed autologous CAR-T therapy in pediatric and young adult B-cell …
-
CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 clinical trial of Venetoclax combined with a pediatric-inspired regimen for newly diagnosed B-cell acute lymphoblastic leukemia is c…
-
CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial is investigating the addition of asciminib to standard treatment for adults with newly diagnosed Philadelphia chrom…
-
CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Clinical Trial of CMD63 Chimeric Antigen Receptor T-cell (CAR T-cell) in Children With Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 clinical trial evaluating CMD63 CAR T-cell therapy in children with relapsed or refractory B-cell acute lymphoblastic leukemia, curr…
-
CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL) [Phase 1]
Phase 1 trial update for a CD19-targeted CAR T cell therapy in pediatric patients with relapsed or refractory B cell acute lymphoblastic leu…
-
CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Expanded Access Program for OOS Obe-cel
Autolus Limited announced an Expanded Access Program for Obe-cel, its CAR-T therapy, to treat adults with acute lymphoblastic leukemia, incl…
-
CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab
A multi-site clinical trial is evaluating how long protective immunity from routine childhood vaccines lasts in participants with B-cell acu…
-
CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Phase 2 Study Assessing the Clinical Activity and Safety of Obecabtagene Autoleucel as a Consolidation in Patients With Newly Diagnosed High-risk B-cell Acute Lymphocytic Leukemia (ALL) [Phase 2]
Phase 2 study evaluating obecabtagene autoleucel as consolidation therapy in newly diagnosed high-risk B-cell acute lymphoblastic leukemia; …
-
CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: CIK Cell Therapy for Relapsed or Refractory Acute B-Lymphoblastic Leukemia: Prognostic Impact on Patients With Early CAR-T Cell Dysfunction [NA]
Clinical trial update on cytokine-induced killer (CIK) cell therapy for relapsed or refractory B-cell acute lymphoblastic leukemia, assessin…
-
CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Clinical Study of SYNCAR-100 in the Treatment of Relapsed/Refractory Acute B-Lymphoblastic Leukemia [EARLY_Phase 1]
An early-phase study of SYNCAR-100 is investigating its use in relapsed/refractory B-cell acute lymphoblastic leukemia. The trial is current…
-
CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 clinical trial evaluating imatinib mesylate in combination with chemotherapy for newly diagnosed Philadelphia chromosome-positive ac…
-
CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Long-term Follow up Local Registry Study of Kymriah in South Korea
This clinical trial update reports a long-term follow-up local registry study of Kymriah in South Korea. Recruitment is ongoing for patients…
-
CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Combination With Low Intensity Chemotherapy in Older Patients With Newly Diagnosed B-cell Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 study evaluating subcutaneous blinatumomab with low-intensity chemotherapy for older patients with newly diagnosed B-cell acute lymp…
-
CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Study of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone for Relapsed B-cell ALL [Phase 1]
A Phase 1 study is evaluating a triplet of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone for relapsed B-cell acute lymphoblastic leuk…
-
CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma [EARLY_Phase 1]
This is an early-phase (Phase 1) clinical trial update for Iomab-ACT, which combines 131-I-labeled apamistamab with CD19-targeted CAR T-cell…
-
CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: This Clinical Trial is a Single-arm, Non-randomized Pilot Trial to Determine the Safety of Administering Autologous Anti-C19 Cells (ARI-0001) and the Feasibility of Local CAR-T Cell Production in Patients Over 18 Years of Age With Relapsed/Refractory (R/R) CD19+ Hematologic Malignancies, Including R [NA]
A single-arm, non-randomized pilot trial to evaluate the safety of autologous anti-CD19 CAR-T cells (ARI-0001) and the feasibility of local …
-
CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease [Phase 2]
Phase 2 clinical trial update evaluating Besponsa (Inotuzumab ozogamicin) for B-cell acute lymphoblastic leukemia with positive minimal resi…
-
CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: BAFFR Targeting CAR-T Cells for the Treatment of Relapsed or Refractory B-cell ALL [Phase 1]
A Phase 1 clinical trial evaluating BAFFR-targeting CAR-T cells for relapsed or refractory B-cell acute lymphoblastic leukemia is currently …