Aplastic Anemia
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CLINICAL_TRIALS other · 2017-08-11Clinical Trial Update: Haploidentical Transplantation in Severe Aplastic Anemia [NA]
This is a clinical trial update for haploidentical transplantation in severe aplastic anemia, but the trial status is currently unknown.
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CLINICAL_TRIALS research · 2017-07-26Clinical Trial Update: Clinical Study of Non Severe Aplastic Anemia Treated With Cyclosporine, Androgen and Levamisole [NA]
A clinical study is evaluating cyclosporine, an androgen, and levamisole for non-severe aplastic anemia, with the current status listed as U…
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia
A multi-center case-control study investigating multiple risk factors for aplastic anemia has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Neuropsychological Effects of Immunosuppressive Treatment in Subjects With Aplastic Anemia
This clinical trial update reports on the neuropsychological effects of immunosuppressive treatment in subjects with aplastic anemia; the st…
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Unrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells [Phase 1]
A Phase 1 trial of unrelated umbilical cord blood transplantation augmented with ALDHbr cord blood cells has completed, with the update desc…
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CLINICAL_TRIALS trial_result · 2017-06-15Clinical Trial Update: Cord Blood Transplantation in Severe Aplastic Anemia [Phase 2]
Phase 2 clinical trial evaluating cord blood transplantation for severe aplastic anemia has completed, including patients with hereditary di…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies [NA]
Clinical trial update for fludarabine-based conditioning prior to allogeneic transplantation in advanced hematologic malignancies; study com…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia [Phase 2]
Phase 2 trial comparing three immunosuppressive regimens for severe aplastic anemia; results of the study have been posted.
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Stem Cell Transplant (SCT) for Dyskeratosis Congenita or SAA [Phase 2, Phase 3]
Completed Phase 2 and Phase 3 clinical trial evaluating stem cell transplant for Dyskeratosis Congenita and Aplastic Anemia; results posted …
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL) [Phase 2]
A phase 2 trial of alemtuzumab in myelodysplastic syndrome, aplastic anemia, and T-cell large granular lymphocytic leukemia was terminated, …
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CLINICAL_TRIALS safety_alert · 2017-04-17Clinical Trial Update: Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone
Clinical trial update reports methemoglobinemia risk in young patients with hematologic cancers or aplastic anemia treated with dapsone in a…
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CLINICAL_TRIALS research · 2017-04-07Clinical Trial Update: Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Aplastic Anemia [Phase 1]
Phase 1 clinical trial evaluating umbilical cord-derived mesenchymal stem cell therapy for aplastic anemia, sponsored by Hebei Medical Unive…
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Allogeneic Stem Cell Transplantation for Patients With Severe Aplastic Anemia [Phase 1]
Phase 1 trial evaluating allogeneic stem cell transplantation for severe aplastic anemia; the study status is completed.
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Cyclophosphamide and Anti-thymocyte Globulin Followed By Methotrexate and Cyclosporine in Preventing Chronic Graft-Versus-Host Disease in Patients With Severe Aplastic Anemia Undergoing Donor Bone Marrow Transplant [Phase 2]
Phase 2 study evaluating a conditioning regimen of cyclophosphamide and anti-thymocyte globulin followed by methotrexate and cyclosporine to…
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FDA approval · 2017-03-09FDA Approved: PROMACTA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for PROMACTA (eltrombopag olamine) by Novartis Pharmaceuticals Corporation. The action updates the p…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA Treatment [Phase 2]
Phase 2 trial evaluating horse T-cell leukemia/lymphoma ATG and cyclosporine in patients with aplastic anemia unresponsive to or suboptimall…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders [Phase 1, Phase 2]
A completed Phase 1/2 study from Singapore General Hospital evaluated a Traditional Chinese Medicine formulation for supportive management o…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: ATG Combined With Cyclophosphamide And Cord Blood Transfusion in Treating Patients With Severe Aplastic Anemia [Phase 4]
This entry provides a Phase 4 clinical trial update evaluating ATG-based therapy with cyclophosphamide and cord blood transfusion for severe…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: Bone Marrow Transplant Trial for Patients With Refractory Severe Aplastic Anemia [Phase 2]
Phase 2 bone marrow transplant trial for patients with refractory severe aplastic anemia was terminated.
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FDA label_change · 2016-10-12FDA Approved: PROMACTA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for PROMACTA (eltrombopag olamine) to update its labeling; this action may include changes to indica…
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Fludarabine-based Conditioning for Severe Aplastic Anemia (BMT CTN 0301) [Phase 1, Phase 2]
A phase 1/2 trial evaluating fludarabine-based conditioning for severe aplastic anemia has completed recruitment with results posted.
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: High-Tc Susceptometer to Monitor Transfusional Iron Overload
Clinical trial update reporting that the study evaluating a High-Tc Susceptometer to monitor transfusional iron overload has completed, in p…
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CLINICAL_TRIALS trial_result · 2016-08-05Clinical Trial Update: Efficacy and Safety of Thrombopoietin In Patients With Severe and Very Severe Aplastic Anemia [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of thrombopoietin in patients with severe and very severe aplastic anemia.
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: A Phase II Study of Umbilical Cord Blood Transplantation [Phase 2]
A Phase II study of Umbilical Cord Blood Transplantation was terminated, with results posted in 2016 for diseases including leukemia, lympho…
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders [Phase 2]
A Phase 2 trial testing nonmyeloablative allogeneic stem cell transplantation from HLA-matched unrelated donors for multiple hematologic dis…