Aplastic Anemia
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Sign up freeTop drugs studied for this disease
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FDA label_change · 2020-07-23FDA Approved: JADENU — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approves a supplemental application for JADENU (deferasirox) from Novartis, updating the product labeling.
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FDA approval · 2020-06-15FDA Approved: DEFERASIROX — Original Application (Amneal Pharmaceuticals NY LLC)
The FDA approved Amneal's generic deferasirox (Deferasirox) as an original ANDA for the treatment of transfusion-related iron overload in pa…
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CLINICAL_TRIALS trial_result · 2020-06-05Clinical Trial Update: Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia [Phase 1, Phase 2]
Clinical trial update of eltrombopag with standard immunosuppression for severe aplastic anemia. The Phase 1/2 study had results posted in 2…
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FDA approval · 2020-04-13FDA Approved: DEFERASIROX — Supplemental Application (Xiromed, LLC)
The FDA approved a supplemental application for deferasirox filed by Xiromed, LLC under an ANDA.
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CLINICAL_TRIALS trial_result · 2020-04-02Clinical Trial Update: King's Invasive Aspergillosis Study II [Phase 4]
A Phase 4 clinical trial update for King's Invasive Aspergillosis Study II (NCT02875743) from King's College Hospital NHS Trust, with condit…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: NMA Allogeneic Hematopoietic Cell Transplant in Hematologic Cancer/Disorders [Phase 2]
Phase 2 trial update of an allogeneic hematopoietic cell transplant in hematologic cancers/disorders; status completed with results posted i…
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CLINICAL_TRIALS trial_result · 2019-08-16Clinical Trial Update: Safety and Efficacy of Exjade in the Treatment of Transfusion-dependent Iron Overload in Aplastic Anemia Patients [Phase 4]
Phase 4 trial update on safety and efficacy of Exjade for transfusion-dependent iron overload in patients with aplastic anemia; study termin…
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CLINICAL_TRIALS trial_result · 2019-08-02Clinical Trial Update: Alemtuzumab to Treat Severe Aplastic Anemia [Phase 2]
Phase 2 trial evaluating alemtuzumab for severe aplastic anemia (refractory/relapse) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A in Naive Aplastic Anemia (AA) Subjects [Phase 2]
Phase 2 trial evaluating eltrombopag in combination with rabbit anti-thymocyte globulin and cyclosporine A in naive aplastic anemia patients…
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CLINICAL_TRIALS trial_result · 2019-05-03Clinical Trial Update: A Study to Assess the Safety and Efficacy of Eltrombopag in Japanese Subjects With Refractory, Moderate or More Severe Aplastic Anemia [Phase 2]
Phase 2 trial assessing safety and efficacy of eltrombopag in Japanese patients with refractory, moderate or more severe aplastic anemia (co…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Eltrombopag for Moderate Aplastic Anemia [Phase 2]
This document summarizes Phase 2 results from a trial of eltrombopag in moderate aplastic anemia, with results posted in 2019.
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FDA approval · 2019-04-18FDA Approved: BUSULFAN — Original Application (Armas Pharmaceuticals Inc.)
FDA approved a generic Busulfan from Armas Pharmaceuticals Inc. under ANDA210931, enabling a generic formulation.
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CLINICAL_TRIALS trial_result · 2019-01-18Clinical Trial Update: Study of High Dose Cyclophosphamide in Patients With Severe Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria [Phase 2]
A Phase 2 study evaluated high-dose cyclophosphamide in patients with severe aplastic anemia and paroxysmal nocturnal hemoglobinuria. The tr…
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CLINICAL_TRIALS trial_result · 2018-12-04Clinical Trial Update: Extended Dosing With Eltrombopag for Severe Aplastic Anemia [Phase 2]
Phase 2 trial update on extended dosing of eltrombopag for severe aplastic anemia completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-11-27Clinical Trial Update: Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients [Phase 2, Phase 3]
Clinical trial update for peripheral blood allogenic stem cell transplantation using non-anti thymocyte globulin regimens in severe aplastic…
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FDA approval · 2018-09-28FDA Approved: BUSULFEX — Supplemental Application (Otsuka America Pharmaceutical, Inc.)
FDA approved a supplemental application for Busultex (busulfan) filed by Otsuka America Pharmaceutical, Inc. The action updates the labeling…
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CLINICAL_TRIALS withdrawal · 2018-07-26Clinical Trial Update: Patient-Driven Transfusion Thresholds in Hematological Disorders: A Pilot Study [NA]
A pilot clinical trial on patient-driven transfusion thresholds in hematological disorders sponsored by Emory University has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-07-16Clinical Trial Update: A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients [Phase 2]
Phase 2 pilot study of eltrombopag in refractory aplastic anemia completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: Danazol for Genetic Bone Marrow and Lung Disorders [Phase 1, Phase 2]
Phase 1/2 trial update for danazol in aplastic anemia and related bone marrow/lung disorders; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine [Phase 2]
Phase 2 trial evaluating hematopoietic stem cell transplantation after a chemotherapy-only cytoreduction with busulfan, cyclophosphamide, an…
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Fertility Preservation in Women Who Will Have Gonadotoxic Therapy or Hematopoetic Stem Cell Transplantation, and in Women With Sickle Cell Disease
A NICHD-sponsored clinical trial on fertility preservation for women undergoing gonadotoxic therapy or hematopoietic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Phase III Randomized Study of Cyclophosphamide With or Without Antithymocyte Globulin Before Bone Marrow Transplantation in Patients With Aplastic Anemia [Phase 3]
Phase III randomized trial comparing cyclophosphamide with or without antithymocyte globulin before bone marrow transplantation in patients …
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Efficacy and Safety of Eltrombopag In Patients With Severe and Very Severe Aplastic Anemia [Phase 2]
Phase 2 trial evaluating eltrombopag for severe, very severe, and moderate aplastic anemia reports efficacy and safety results.
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FDA approval · 2017-10-04FDA Approved: PROMACTA — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for PROMACTA (eltrombopag olamine) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias [Phase 2]
Phase 2 study of deferasirox for iron overload in beta-thalassemia patients who cannot be treated with deferoxamine, as well as related chro…