Apical Periodontitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Comparison of the Effects of N-acetylcysteine, Calcium Hydroxide, and Double Antibiotic Paste [NA]
A completed clinical trial compared N-acetylcysteine, calcium hydroxide, and double antibiotic paste for chronic apical periodontitis.
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Sealers in Chronic Apical Lesions [NA]
A completed clinical trial from Kahramanmaras Sutcu Imam University evaluating endodontic sealers for chronic apical lesions, examining apic…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Post-operative Pain After Different Irrigation and Disinfection Methods in Single-rooted Teeth [NA]
Completed clinical trial comparing different irrigation and disinfection methods in single-rooted teeth. The study evaluated postoperative p…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: CGF-Enhanced Autologous Pulp Transplantation in Mature Necrotic Teeth [NA]
Completed clinical trial evaluating CGF-Enhanced Autologous Pulp Transplantation in mature necrotic teeth.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Clinical Efficacy of AH Plus Bioceramic Sealer [NA]
A Kuwait Ministry of Health-sponsored clinical trial is evaluating the efficacy of AH Plus Bioceramic Sealer for treating root canal infecti…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Comparative Evaluation of Clinical and Radiographic Treatment Outcomes of Garlic Gel and Calcium Hydroxide as an Intracanal Medicament in Nonsurgical Root Canal Treatment of Permanent Teeth. [Phase 3]
A Phase 3 clinical trial comparing garlic gel to calcium hydroxide as an intracanal medicament in nonsurgical root canal treatment; currentl…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Inflammation-Related Endothelial Barrier Dysfunction in Patients With Apical Periodontitis
A completed clinical trial from the University of Turin evaluating inflammation-related endothelial barrier dysfunction in patients with api…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis [Phase 2]
Phase 2 clinical trial assessing N-acetylcysteine as part of root canal treatment for necrotic teeth with apical periodontitis; study is act…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Evaluation of Postoperative Pain and Lesion Healing in Periapical Lesion-Affected Teeth Obturated With Different Root Canal Sealers [NA]
This clinical trial evaluates postoperative pain and lesion healing in teeth with periapical lesions treated using different root canal seal…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Neurokinin A and Matrix Metalloproteinase 9 Levels in Gingival Crevicular Fluid Samples of Teeth With Symptomatic Irreversible Pulpitis With Symptomatic Apical Periodontitis
This clinical trial entry describes a study measuring neurokinin A and matrix metalloproteinase-9 levels in gingival crevicular fluid from t…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: The Present Study Aims to Follow up on All Root Canal Treatments Performed During the Year 2023 Within the Public Dental Services of the Counties of Jönköping, Kalmar, and Östergötland, Sweden. The Study is Entirely Observational in Nature.
An observational study in Sweden will follow up all root canal treatments performed in 2023 within public dental services in Jönköping, Kalm…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Examination of the Effect of Nd:YAG Laser on Oxidative Stress and Matrix Metalloproteinase-9 in Teeth With Apical Periodontitis
This clinical trial evaluated whether Nd:YAG laser affects oxidative stress and matrix metalloproteinase-9 in teeth with apical periodontiti…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Comparison of Sonic and Ultrasonic Activation on Healing of Apical Periodontitis [NA]
A completed clinical trial comparing sonic activation versus ultrasonic activation for healing apical periodontitis. The status indicates co…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Pulp Transplantation in Necrotic Mature Teeth With Periapical Radiolucency [NA]
This entry notes the completion of a clinical trial evaluating pulp transplantation for regenerating dental pulp in necrotic mature teeth wi…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Effect of Probiotics, Double Antibiotic Paste, and Calcium Hydroxide on Postoperative Pain in Irreversible Pulpitis: A Randomized Trial [NA]
Completed randomized trial evaluating the effects of probiotics, double antibiotic paste, and calcium hydroxide on postoperative pain in irr…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: A Comparative Analysis of Biomaterials for Retrograde Filling in Apical Surgery. [NA]
This Clinical Trial Update reports a comparative analysis of biomaterials for retrograde filling in apical surgery to treat apical periodont…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: The Effect of Different Intracanal Medicaments on Periapical Lesion Healing [NA]
This clinical trial evaluates how different intracanal medicaments affect healing of apical periodontitis-related periapical lesions, and th…
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: The Success of Root Canal Treatments Performed Using Two Different Intracanal Medicaments [NA]
A clinical trial evaluating outcomes of root canal treatment using two different intracanal medicaments.
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: The Efficiency of 810 nm Diode Laser on Periapical Healing After Root Canal Retreatment [NA]
Clinical trial evaluating 810 nm diode laser disinfection to improve periapical healing after root canal retreatment is currently recruiting…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Using Platelet-rich Fibrin in Regenerative Endodontic Treatment in Mature Permanent Teeth [NA]
This clinical trial update concerns using platelet-rich fibrin in regenerative endodontic treatment for mature permanent teeth, sponsored by…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Effect of Ozone Use in Intracanal Irrigation on Oxidative Stress Level in Teeth With Asymptomatic Apical Periodontitis [NA]
This clinical trial update describes an ongoing study evaluating the effect of ozone-based intracanal irrigation on oxidative stress in teet…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: To Evaluate Periapical Healing Post Full Pulpotomy in Teeth With and Without Apical Periodontitis [NA]
This clinical trial evaluates periapical healing after full pulpotomy in teeth with and without apical periodontitis. The study status is NO…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: The Effect of Using Octenidine Hydrochloride as a Final Irrigation Solution on Teeth With Asymptomatic Apical Periodontitis on Postoperative Pain and Treatment Success: A Prospective Randomized Clinical Study [NA]
A completed randomized trial evaluated whether using octenidine hydrochloride as the final irrigation solution reduces postoperative pain an…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Evaluation of Periapical Healing Following Endodontic Microsurgery With Leukocyte and Platelet Rich Fibrin (L-PRF)
This clinical trial from the University of Pennsylvania evaluates periapical healing after endodontic microsurgery using leukocyte- and plat…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Effectiveness of GentleWave on the Healing of Apical Periodontitis: A Prospective Cohort Study [NA]
A prospective cohort trial assessing the effectiveness of the GentleWave system in healing apical periodontitis, which has been terminated.