Antibody-mediated Rejection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Update: A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) [Phase 3]
Phase 3 clinical trial evaluating the safety and effects of felzartamab infusions in adults with antibody-mediated rejection after kidney tr…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Study to Learn More About the Long-Term Safety and Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) [Phase 3]
A Phase 3 clinical trial updating on long-term safety and effects of felzartamab infusions in adults with kidney transplants experiencing an…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study to Learn More About the Long-Term Safety and Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) [Phase 3]
Phase 3 study to assess long-term safety and effects of felzartamab infusions in adults with antibody-mediated rejection after kidney transp…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation [Phase 2]
Phase 2 study evaluating ALXN2030 for antibody-mediated rejection in kidney transplant patients is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Peripheral and Intrarenal B Cell Study in Antibody Mediated Transplant Rejection : Phenotypic and Transcriptional Study, Study of Reactivity
A recruiting clinical study evaluating peripheral and intrarenal B cells in antibody-mediated rejection after kidney transplantation, focusi…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by Prefilled Syringe in Kidney Transplant Recipients With Antibody-Mediated Rejection (AMR) [Phase 2]
Phase 2 trial to evaluate the safety and tolerability of subcutaneous Efgartigimod PH20 given by prefilled syringe in kidney transplant reci…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Impact of ExtraCorporeal Phototherapy (ECP) on Auxiliary Follicular T-lymphocytes and Circulating B-lymphocytes During Chronic AntiBody-Mediated Rejection in Kidney Transplantation. [NA]
This clinical trial investigates how extracorporeal photopheresis (ECP) affects auxiliary follicular T-lymphocytes and circulating B-lymphoc…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: VIRTUUS Children's Study
The VIRTUUS Children's Study (NCT03719339) sponsored by Children's Hospital of Philadelphia is currently active but not recruiting, focusing…
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CLINICAL_TRIALS withdrawal · 2025-11-20Clinical Trial Update: Eculizumab Therapy for Subclinical Antibody-mediated Rejection in Kidney Transplantation [Phase 1, Phase 2]
A Phase 1/2 trial evaluating eculizumab for subclinical acute antibody-mediated rejection in kidney transplantation has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Comparison Between Bortezomib and Rituximab Plus Plasmapheresis in AMR [NA]
A completed clinical trial comparing bortezomib to rituximab plus plasmapheresis for antibody-mediated rejection.
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients [Phase 3]
A Phase 3 trial of clazakizumab for chronic active antibody-mediated rejection in kidney transplant recipients was terminated, with results …
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Quantitative Parameters of HLA-DQ Antibodies in Lung Transplantation
A completed clinical trial update reporting quantitative parameters of HLA-DQ antibodies in lung transplantation, with relevance to antibody…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Allogeneic Umbilical Cord Mesenchymal Stromal Cells for the Treatment of Chronic Antibody-Mediated Rejection in Kidney Transplantation [Phase 2]
Phase 2 clinical trial evaluating allogeneic umbilical cord mesenchymal stromal cells for chronic antibody-mediated rejection in kidney tran…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Biorepository and Registry for Plasma Exchange Patients
A clinical trial update announcing a biorepository and registry for patients undergoing plasma exchange, with recruiting status and listed i…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Diagnostic Efficacy of Molecular Diagnostic Method for AMR in ABOiKT [NA]
A completed clinical trial evaluated the diagnostic efficacy of a molecular diagnostic method for detecting antibody-mediated rejection in A…
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Clazakizumab for Chronic and Active Antibody Mediated Rejection Post-Kidney Transplant [Phase 1, Phase 2]
The trial update reports Phase 1/2 results for clazakizumab in chronic and active antibody-mediated rejection after kidney transplantation, …
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Longitudinal Changes in Donor-Derived Cell-Free DNA With Tocilizumab Treatment for Chronic Antibody-Mediated Rejection
A clinical trial update investigates longitudinal changes in donor-derived cell-free DNA with tocilizumab treatment for chronic antibody-med…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Transplant Antibody-Mediated Rejection: Guiding Effective Treatments [Phase 3]
A Phase 3 clinical trial evaluating treatments for antibody-mediated rejection in kidney transplant patients has been terminated.
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: TocIlizumab in Late/Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients [Phase 3]
Clinical trial update for a Phase 3 study of tocilizumab in late/chronic active antibody-mediated rejection after kidney transplantation. Th…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant [Phase 1, Phase 2]
Clinical trial update on clazakizumab for highly HLA-sensitized patients awaiting kidney transplant; the study spans Phase 1/2 with status A…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Donor-derived Cell-free DNA for Early Diagnosis of Antibody-mediated Rejection [NA]
A completed study from Charité University evaluated donor-derived cell-free DNA as an early diagnostic biomarker for antibody-mediated rejec…
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: CARdiac Imaging and BIomarkers in the Diagnosis of Antibody Mediated Rejection in Heart Transplantation
This clinical trial aims to evaluate cardiac imaging and biomarkers for diagnosing antibody-mediated rejection in heart transplant recipient…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: A Prospective Randomized Trial of ECP in Subclinical AMR [NA]
Status update on a prospective randomized trial evaluating extracorporeal photopheresis for subclinical antibody-mediated rejection in lung …
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: Felzartamab in Late Antibody-Mediated Rejection [Phase 2]
Phase 2 clinical trial update for felzartamab in antibody-mediated rejection has completed.
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Desensitization in Kidney Allograft Using Daratumumab [Phase 1, Phase 2]
Phase 1/2 trial evaluating desensitization in kidney transplantation using daratumumab has been completed.