Antibody-mediated Rejection

• CLINICAL_TRIALS trial_result · 2022-01-18
  Clinical Trial Update: Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients [Phase 3]

  A Phase 3 trial evaluating human plasma-derived C1-esterase inhibitor as add-on therapy to standard of care for refractory antibody-mediated…

• CLINICAL_TRIALS trial_result · 2021-11-02
  Clinical Trial Update: Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation [Phase 2]

  Phase 2 pilot study of belatacept for immunosuppression in lung transplant recipients has completed with posted results.

• CLINICAL_TRIALS trial_result · 2020-09-09
  Clinical Trial Update: A Pilot Trial of Clazakizumab in Late ABMR [Phase 2]

  A Phase 2 pilot trial evaluating clazakizumab for antibody-mediated rejection has completed recruitment.

• CLINICAL_TRIALS trial_result · 2020-07-13
  Clinical Trial Update: A Multicenter Study to Evaluate the Efficacy and Safety of Cinryze® for the Treatment of Acute Antibody-mediated Rejection in Participants With Kidney Transplant [Phase 3]

  Phase 3 trial evaluating Cinryze for acute antibody-mediated rejection in kidney transplant recipients was terminated with results posted in…

• CLINICAL_TRIALS trial_result · 2019-07-05
  Clinical Trial Update: Belatacept (Nulojix) in Renal Transplant Recipient With Mild Immunologic Risk Factor: a Pilot Prospective Study. [Phase 2]

  Phase 2 pilot prospective study evaluating belatacept (Nulojix) in renal transplant recipients with mild immunologic risk factors, including…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS research · 2019-01-28
  Clinical Trial Update: Antibodies and Liver Retransplantation

  A clinical trial update concerning the use of antibodies in liver retransplantation for liver transplant failure and antibody-mediated rejec…

• CLINICAL_TRIALS trial_result · 2018-12-17
  Clinical Trial Update: Belatacept in Kidney Transplantation of Moderately Sensitized Patients [Phase 4]

  A Phase 4 clinical trial evaluating belatacept in moderately sensitized kidney transplant patients has been withdrawn.

• CLINICAL_TRIALS trial_result · 2018-04-19
  Clinical Trial Update: Cyclophosphamide Therapy for Refractory Antibody-Mediated Rejection (AMR) in Kidney Transplants [Phase 2]

  Phase 2 clinical trial evaluating cyclophosphamide therapy for refractory antibody-mediated rejection in kidney transplant recipients. The s…

• CLINICAL_TRIALS trial_result · 2017-09-21
  Clinical Trial Update: Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation [Phase 2]

  Phase 2 trial of eculizumab for antibody-mediated rejection after kidney transplant was terminated; results posted in 2017.

• CLINICAL_TRIALS trial_result · 2017-04-19
  Clinical Trial Update: Safety & Efficacy of Eculizumab to Prevent AMR in Living Donor Kidney Transplant Recipients Requiring Desensitization [Phase 2]

  Phase 2 trial evaluating safety and efficacy of eculizumab to prevent antibody-mediated rejection in living donor kidney transplant recipien…

• CLINICAL_TRIALS trial_result · 2015-09-30
  Clinical Trial Update: Effect of BM-MSCs on Chronic AMR After Kidney Transplantation [Phase 1, Phase 2]

  This document reports on a Phase 1/Phase 2 trial evaluating bone marrow-derived mesenchymal stem cells (BM-MSCs) for chronic antibody-mediat…

• CLINICAL_TRIALS withdrawal · 2012-02-17
  Clinical Trial Update: Recombinant Human C1 Inhibitor for the Treatment of Early Antibody-Mediated Rejection in Renal Transplantation [Phase 2]

  A Phase 2 trial evaluating recombinant human C1 esterase inhibitor for early antibody-mediated rejection in kidney transplantation has been …