Antibody-mediated Rejection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Update: A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) [Phase 3]
Phase 3 clinical trial evaluating the safety and effects of felzartamab infusions in adults with antibody-mediated rejection after kidney tr…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Study to Learn More About the Long-Term Safety and Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) [Phase 3]
A Phase 3 clinical trial updating on long-term safety and effects of felzartamab infusions in adults with kidney transplants experiencing an…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Comparison Between Bortezomib and Rituximab Plus Plasmapheresis in AMR [NA]
A completed clinical trial comparing bortezomib to rituximab plus plasmapheresis for antibody-mediated rejection.
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients [Phase 3]
A Phase 3 trial of clazakizumab for chronic active antibody-mediated rejection in kidney transplant recipients was terminated, with results …
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Quantitative Parameters of HLA-DQ Antibodies in Lung Transplantation
A completed clinical trial update reporting quantitative parameters of HLA-DQ antibodies in lung transplantation, with relevance to antibody…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Diagnostic Efficacy of Molecular Diagnostic Method for AMR in ABOiKT [NA]
A completed clinical trial evaluated the diagnostic efficacy of a molecular diagnostic method for detecting antibody-mediated rejection in A…
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Clazakizumab for Chronic and Active Antibody Mediated Rejection Post-Kidney Transplant [Phase 1, Phase 2]
The trial update reports Phase 1/2 results for clazakizumab in chronic and active antibody-mediated rejection after kidney transplantation, …
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant [Phase 1, Phase 2]
Clinical trial update on clazakizumab for highly HLA-sensitized patients awaiting kidney transplant; the study spans Phase 1/2 with status A…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Donor-derived Cell-free DNA for Early Diagnosis of Antibody-mediated Rejection [NA]
A completed study from Charité University evaluated donor-derived cell-free DNA as an early diagnostic biomarker for antibody-mediated rejec…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: A Prospective Randomized Trial of ECP in Subclinical AMR [NA]
Status update on a prospective randomized trial evaluating extracorporeal photopheresis for subclinical antibody-mediated rejection in lung …
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: Felzartamab in Late Antibody-Mediated Rejection [Phase 2]
Phase 2 clinical trial update for felzartamab in antibody-mediated rejection has completed.
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Desensitization in Kidney Allograft Using Daratumumab [Phase 1, Phase 2]
Phase 1/2 trial evaluating desensitization in kidney transplantation using daratumumab has been completed.
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CLINICAL_TRIALS trial_result · 2022-01-18Clinical Trial Update: Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients [Phase 3]
A Phase 3 trial evaluating human plasma-derived C1-esterase inhibitor as add-on therapy to standard of care for refractory antibody-mediated…
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CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation [Phase 2]
Phase 2 pilot study of belatacept for immunosuppression in lung transplant recipients has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-09-09Clinical Trial Update: A Pilot Trial of Clazakizumab in Late ABMR [Phase 2]
A Phase 2 pilot trial evaluating clazakizumab for antibody-mediated rejection has completed recruitment.
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CLINICAL_TRIALS trial_result · 2020-07-13Clinical Trial Update: A Multicenter Study to Evaluate the Efficacy and Safety of Cinryze® for the Treatment of Acute Antibody-mediated Rejection in Participants With Kidney Transplant [Phase 3]
Phase 3 trial evaluating Cinryze for acute antibody-mediated rejection in kidney transplant recipients was terminated with results posted in…
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: Belatacept (Nulojix) in Renal Transplant Recipient With Mild Immunologic Risk Factor: a Pilot Prospective Study. [Phase 2]
Phase 2 pilot prospective study evaluating belatacept (Nulojix) in renal transplant recipients with mild immunologic risk factors, including…
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CLINICAL_TRIALS trial_result · 2018-12-17Clinical Trial Update: Belatacept in Kidney Transplantation of Moderately Sensitized Patients [Phase 4]
A Phase 4 clinical trial evaluating belatacept in moderately sensitized kidney transplant patients has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: Cyclophosphamide Therapy for Refractory Antibody-Mediated Rejection (AMR) in Kidney Transplants [Phase 2]
Phase 2 clinical trial evaluating cyclophosphamide therapy for refractory antibody-mediated rejection in kidney transplant recipients. The s…
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CLINICAL_TRIALS trial_result · 2017-09-21Clinical Trial Update: Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation [Phase 2]
Phase 2 trial of eculizumab for antibody-mediated rejection after kidney transplant was terminated; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: Safety & Efficacy of Eculizumab to Prevent AMR in Living Donor Kidney Transplant Recipients Requiring Desensitization [Phase 2]
Phase 2 trial evaluating safety and efficacy of eculizumab to prevent antibody-mediated rejection in living donor kidney transplant recipien…
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: Effect of BM-MSCs on Chronic AMR After Kidney Transplantation [Phase 1, Phase 2]
This document reports on a Phase 1/Phase 2 trial evaluating bone marrow-derived mesenchymal stem cells (BM-MSCs) for chronic antibody-mediat…