Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: Muscle Training of Patients With Amyotrophic Lateral Sclerosis (ALS) [NA]
A completed clinical trial conducted by the University of Southern Denmark evaluated muscle training in patients with amyotrophic lateral sc…
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)
The clinical trial completed a study validating biomarkers in amyotrophic lateral sclerosis and related motor neuron diseases, evaluating ca…
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)
This report summarizes a completed clinical trial studying cortex changes during real and imagined movements in people with amyotrophic late…
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: sCD163 in ALS Patients
A completed clinical trial at University of Aarhus investigated soluble CD163 in patients with amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Study of Electrical Impedance Myography (EIM) in ALS
This update reports on the completed clinical trial evaluating Electrical Impedance Myography (EIM) in amyotrophic lateral sclerosis and rel…
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CLINICAL_TRIALS trial_result · 2016-05-04Clinical Trial Update: Nightime NIV Initiation in Amyotrophic Lateral Sclerosis in an Outpatient Setting [NA]
The document notes the completion of a clinical trial evaluating initiating nighttime noninvasive ventilation for individuals with amyotroph…
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CLINICAL_TRIALS research · 2016-05-03Clinical Trial Update: A Study to Evaluate the Performance of a Diagnostic Test in ALS
This document reports a study to evaluate the performance of a diagnostic test for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Trial of Resistance and Endurance Exercise in Amyotrophic Lateral Sclerosis (ALS) [NA]
This entry notes that the Johns Hopkins University trial evaluating resistance and endurance exercise in amyotrophic lateral sclerosis has c…
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FDA approval · 2016-03-30FDA Approved: RILUZOLE — Original Application (Ascend Laboratories, LLC)
FDA approved the original application for riluzole by Ascend Laboratories, LLC.
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis [Phase 1]
A Phase 1 trial evaluating transplantation of human spinal cord-derived neural stem cells (NSI-566) for amyotrophic lateral sclerosis, spons…
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS [Phase 3]
A Phase 3 clinical trial evaluating vitamin E for muscular cramps in patients with amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: Impact of Early Non Invasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) Patients [NA]
A clinical trial evaluating early non-invasive ventilation in amyotrophic lateral sclerosis has completed. The snippet does not include tria…
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CLINICAL_TRIALS trial_result · 2016-02-04Clinical Trial Update: Feasibility of Telesurveillance and Home Cough Assistance for Amyotrophic Lateral Patients (ALS) [Phase 4]
Phase 4 trial assessing the feasibility of telesurveillance and home cough assistance for amyotrophic lateral sclerosis; the study has compl…
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CLINICAL_TRIALS trial_result · 2016-02-01Clinical Trial Update: Compassionate Treatment : An Exploratory Clinical Trial to Assess Treatment of Amyotrophic Lateral Sclerosis [Phase 1]
This update notes the completion of a Phase 1 exploratory clinical trial conducted at China Medical University Hospital evaluating a compass…
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Tongue Strength in Amyotrophic Lateral Sclerosis (ALS) [NA]
A clinical trial update examining tongue strength in individuals with amyotrophic lateral sclerosis (ALS); the current trial status is not d…
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: An Open Label, Safety and Tolerability Continuation Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
This update notes the termination of an open-label safety and tolerability continuation study of intracerebroventricular sNN0029 in patients…
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: A Safety Study of sNN0029 Administration Via Intracerebroventricular Route to Patients With ALS [Phase 1]
Phase 1 safety study of sNN0029 administered via intracerebroventricular route in patients with Amyotrophic Lateral Sclerosis has been termi…
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: A follow-on Study to Assess Long-term Safety and Tolerability of i.c.v Administration of sNN0029 in Patients With ALS [Phase 1]
A Phase 1 clinical trial evaluating the long-term safety and tolerability of intracerebroventricular administration of sNN0029 in patients w…
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CLINICAL_TRIALS withdrawal · 2016-01-14Clinical Trial Update: Mesenchymal Stem Cell Injection in Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
Phase 1/2 trial of mesenchymal stem cell injections for amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-01-07Clinical Trial Update: Optimizing NIPPV Use for Patients With ALS [NA]
A completed clinical trial investigating optimal use of non-invasive ventilation (NIPPV) in patients with amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Acetylcholine Receptors From Human Muscles as Pharmacological Target for ALS [NA]
A university-led clinical trial explored acetylcholine receptors from human muscles as a pharmacological target for amyotrophic lateral scle…
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CLINICAL_TRIALS withdrawal · 2016-01-01Clinical Trial Update: Intraventricular Transplantation of Mesenchymal Stem Cell in Patients With ALS [Phase 1]
A phase 1 trial evaluating intraventricular transplantation of mesenchymal stem cells in patients with amyotrophic lateral sclerosis was wit…
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CLINICAL_TRIALS trial_result · 2015-12-31Clinical Trial Update: Gilenya in Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
This document reports the completion and results posting of a Phase 2 trial of fingolimod (Gilenya) in amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2015-12-30Clinical Trial Update: Human Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis (ALS) [Phase 1]
This Phase 1 clinical trial evaluated transplantation of human neural stem cells in patients with amyotrophic lateral sclerosis and has comp…
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CLINICAL_TRIALS research · 2015-12-22Clinical Trial Update: Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation [Phase 3]
A Phase 3 trial evaluating phrenic stimulation for respiratory insufficiency in amyotrophic lateral sclerosis was terminated.