Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-08-23Clinical Trial Update: HEALEY ALS Platform Trial - Regimen D Pridopidine [Phase 2, Phase 3]
Phase 2/3 results for pridopidine in Regimen D within the HEALEY ALS Platform Trial for amyotrophic lateral sclerosis have been completed an…
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: Study to Investigate the Safety of the Transplantation (by Injection) of Human Glial Restricted Progenitor Cells (hGRPs; Q-Cells®) Into Subjects With Amyotrophic Lateral Sclerosis (ALS) [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating the safety of intrathecal transplantation of human glial restricted progenitor cells (Q-Cells) in adu…
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CLINICAL_TRIALS trial_result · 2023-07-28Clinical Trial Update: An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 (Tofersen) in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS) [Phase 3]
Phase 3 trial of BIIB067 (tofersen) in adults with inherited ALS completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-07-25Clinical Trial Update: HEALEY ALS Platform Trial - Regimen A Zilucoplan [Phase 2, Phase 3]
Phase 2/3 results for Zilucoplan within the HEALEY ALS Platform Trial Regimen A in amyotrophic lateral sclerosis have been completed with re…
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CLINICAL_TRIALS trial_result · 2023-07-25Clinical Trial Update: HEALEY ALS Platform Trial - Regimen C CNM-Au8 [Phase 2, Phase 3]
A Phase 2/3 HEALEY ALS Platform Trial evaluating Regimen C CNM-Au8 for amyotrophic lateral sclerosis has completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Study of AMX0035 in Patients With ALS [Phase 1, Phase 2]
Clinical trial update describing pharmacokinetic and pharmacodynamic study of AMX0035 in ALS patients (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2023-07-20Clinical Trial Update: Targeting Metabolic Flexibility in Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 trial investigating metabolic flexibility as a therapeutic approach for amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2023-07-10Clinical Trial Update: Safety and Efficacy of TUDCA as add-on Treatment in Patients Affected by ALS [Phase 3]
A Phase 3 clinical trial evaluating TUDCA as an add-on treatment for amyotrophic lateral sclerosis (ALS) is in progress, with status current…
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CLINICAL_TRIALS trial_result · 2023-06-28Clinical Trial Update: Multiple Doses of AT-1501-A201 in Adults With ALS [Phase 2]
Phase 2 trial in adults with amyotrophic lateral sclerosis (ALS) evaluating multiple doses of AT-1501-A201 has completed; results posted in …
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: A Study in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial in patients with amyotrophic lateral sclerosis (ALS) sponsored by Eisai Co., Ltd.
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: A Long-Term Study in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2, Phase 3]
A long-term study in amyotrophic lateral sclerosis (ALS) is reported as completed for a Phase 2/Phase 3 trial.
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CLINICAL_TRIALS trial_result · 2023-06-12Clinical Trial Update: HEALEY ALS Platform Trial - Regimen B Verdiperstat [Phase 2, Phase 3]
Phase 2/3 results for Verdiperstat under the HEALEY ALS Platform Trial in amyotrophic lateral sclerosis have been completed with results pos…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: Effectiveness of Expiratory Muscle Strength Training for Improving Communication in ALS [NA]
Completed clinical trial evaluating expiratory muscle strength training to improve communication in amyotrophic lateral sclerosis. Results p…
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: The Effect of RNS60 on ALS Biomarkers [Phase 2]
Phase 2 trial assessing the effect of RNS60 on ALS biomarkers has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-04-07Clinical Trial Update: A Compassionate Use Protocol of AMX0035 for Treatment of Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2, Phase 3]
A compassionate use protocol update for AMX0035 in ALS has completed Phase 2 and Phase 3 trials.
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CLINICAL_TRIALS trial_result · 2023-04-03Clinical Trial Update: Efficacy of Cannabinoids in Amyotrophic Lateral Sclerosis or Motor Neurone Disease [Phase 3]
Phase 3 clinical trial updating the efficacy of cannabinoids in amyotrophic lateral sclerosis (ALS) / motor neuron disease.
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CLINICAL_TRIALS trial_result · 2023-04-03Clinical Trial Update: EMERALD TRIAL Open Label Extension Study [Phase 4]
Open-label extension study update for the EMERALD trial (Phase 4) with conditions including amyotrophic lateral sclerosis and cannabis-relat…
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: Diaphragm Pacing System (DPS) In Participants With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 trial update for diaphragm pacing system in participants with amyotrophic lateral sclerosis (ALS) has completed.
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label Extension [Phase 3]
Open-label Phase 3 extension study evaluating oral levosimendan effects on respiratory function in Amyotrophic Lateral Sclerosis was termina…
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: Impact of Nuedexta on Bulbar Physiology and Function in ALS [Phase 1, Phase 2]
Phase 1/2 trial evaluating the impact of Nuedexta on bulbar physiology and function in amyotrophic lateral sclerosis has been completed with…
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: iPSC-based Drug Repurposing for ALS Medicine (iDReAM) Study [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial update for an iPSC-based drug repurposing study (iDReAM) in amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: Open Label Extension of TUDCA-ALS Study [Phase 3]
Open-label extension update for a Phase 3 TUDCA-ALS trial investigating amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2023-03-01Clinical Trial Update: Colchicine for Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial investigating colchicine for amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2023-01-10Clinical Trial Update: An Efficacy and Safety Study of Ravulizumab in ALS Participants [Phase 3]
Phase 3 trial evaluating ravulizumab in Amyotrophic Lateral Sclerosis (ALS) was terminated; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2022-11-29Clinical Trial Update: Therapy in Amyotrophic Lateral Sclerosis (TAME) [Phase 2]
Phase 2 trial update for a therapy in amyotrophic lateral sclerosis and frontotemporal dementia; trial completed with results posted in 2022…