Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031) [Phase 3]
Phase 3 open-label extension of COURAGE-ALS investigating CY 5031 was terminated; results were posted in August 2024.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Factors Associated With Success of NIPPV in ALS Patients
A completed clinical trial update examines factors associated with successful non-invasive ventilation in patients with amyotrophic lateral …
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
A Phase 2 clinical trial evaluating CNM-Au8, a therapeutic nanocatalyst, in slowing disease progression for amyotrophic lateral sclerosis ha…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Remote Pulmonary Function Testing and Nurse Coaching in ALS [NA]
This clinical trial update reports results from a study evaluating remote pulmonary function testing and nurse coaching in amyotrophic later…
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: Patient's TeleMonitoring With Amyotrophic Lateral Sclerosis Treated by Non Invasive Ventilation at Home. [NA]
This clinical trial update reports the completion of a study evaluating telemonitoring for amyotrophic lateral sclerosis patients treated wi…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Phase 2, Randomized, Double Blind, Placebo Controlled Multicenter Study of Autologous MSC-NTF Cells in Patients With ALS [Phase 2]
Phase 2 randomized, double-blind, placebo-controlled multicenter study of autologous MSC-NTF cells in amyotrophic lateral sclerosis has comp…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Trial of Oxaloacetate in ALS [Phase 1]
Phase 1 trial of oxaloacetate for amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Reducing Disparities in the Quality of Advance Care Planning for Older Adults [NA]
A Duke University-sponsored trial examining disparities in the quality of advance care planning for older adults has completed.
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Environmental Exposure and Neurological Diseases Questionnaire
The trial update notes the completion of a Dartmouth-Hitchcock study examining environmental exposure and its relation to neurological disea…
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients [Phase 3]
Phase 3 trial assessing repeated administrations of NurOwn for amyotrophic lateral sclerosis (ALS) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: Olanzapine for the Treatment of Appetite Loss in Amyotrophic Lateral Sclerosis (ALS) [Phase 2, Phase 3]
Phase 2/Phase 3 trial investigating olanzapine for appetite loss in amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: Safety and Tolerability of Anakinra in Combination With Riluzol in Amyotrophic Lateral Sclerosis [Phase 2]
A Phase 2 clinical trial evaluated the safety and tolerability of combining anakinra with riluzole in patients with amyotrophic lateral scle…
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CLINICAL_TRIALS trial_result · 2024-01-26Clinical Trial Update: Enoxacin for Amyotrophic Lateral Sclerosis (ALS) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating enoxacin for amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2024-01-24Clinical Trial Update: Clinical Pharmacology Study of Oral Edaravone in Amyotrophic Lateral Sclerosis Patients With Gastrostomy [Phase 1]
Phase 1 pharmacology study evaluating oral edaravone in amyotrophic lateral sclerosis patients with gastrostomy; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-01-24Clinical Trial Update: Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis [Phase 1]
A Phase 1 clinical pharmacology study evaluating oral edaravone in Japanese patients with amyotrophic lateral sclerosis has completed, with …
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS) [Phase 1]
Phase 1 clinical trial evaluating suppression of HERV-K with antiretroviral therapy in volunteers with amyotrophic lateral sclerosis has com…
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: Inhibition of Rho Kinase (ROCK) With Fasudil as Disease-modifying Treatment for ALS [Phase 2]
Phase 2 clinical trial investigating ROCK inhibitor fasudil as a disease-modifying treatment for amyotrophic lateral sclerosis has completed…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Clinical Study to Evaluate the Efficacy and Safety of FB1006 in the Treatment of ALS Patients [Phase 4]
A Phase 4 clinical trial evaluating the efficacy and safety of FB1006 in treating amyotrophic lateral sclerosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-10-11Clinical Trial Update: 3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 clinical trial of 3K3A-APC for amyotrophic lateral sclerosis has completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-09-29Clinical Trial Update: Masitinib in Combination With Riluzole for the Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS) [Phase 2, Phase 3]
A clinical trial update reports Phase 2 and Phase 3 studies of masitinib in combination with riluzole for ALS; the trial status is completed…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Trial of Theracurmin for Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 trial results for Theracurmin in amyotrophic lateral sclerosis have been completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Safety Study of VM202 to Treat Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
Safety study results for VM202 in amyotrophic lateral sclerosis (Phase 1/Phase 2) have been completed, and results were posted in September …
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CLINICAL_TRIALS trial_result · 2023-09-07Clinical Trial Update: A Double-blind Randomised, Placebo-controlled Clinical Trial to Test Ambroxol Treatment in ALS [Phase 2]
A Phase 2 double-blind, randomized, placebo-controlled trial evaluating ambroxol treatment for Amyotrophic Lateral Sclerosis.
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CLINICAL_TRIALS trial_result · 2023-08-24Clinical Trial Update: Arimoclomol in Amyotropic Lateral Sclerosis [Phase 3]
Phase 3 trial of arimoclomol in amyotrophic lateral sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-24Clinical Trial Update: Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension Trial [Phase 3]
Open-label extension trial update for arimoclomol in amyotrophic lateral sclerosis (Phase 3) has been terminated, with results posted.