Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: A Follow up Study to Protocol 101/2 - Continued Treatment by IPL344 IV [Phase 2]
The Phase 2 follow-up study of IPL344 IV for amyotrophic lateral sclerosis has been suspended.
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Study of ANX005 in Adults With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 study of ANX005 in adults with amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: A Study to Assess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as Capsules to Healthy Adult Male Participants (Part B) [Phase 1]
This Phase 1 study evaluated the effect of erythromycin (Part A) and itraconazole (Part B) on SAR443820 pharmacokinetics when taken orally i…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZYIL1 in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
This clinical trial update summarizes Phase 2 results for ZYIL1 in amyotrophic lateral sclerosis, including efficacy, safety, tolerability, …
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP [NA]
A National Taiwan University Hospital-sponsored clinical trial is recruiting to evaluate plasmapheresis in amyotrophic lateral sclerosis pat…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral Sclerosis [Phase 2]
This document reports Phase 2 trial results for ranolazine in amyotrophic lateral sclerosis, focusing on safety and efficacy, with the study…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 3]
Phase 3 study of Reldesemtiv in amyotrophic lateral sclerosis was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Geometrical Facial Deformation According to Posture in Amyotrophic Lateral Sclerosis
This clinical trial update reports results on geometrical facial deformation according to posture in Amyotrophic Lateral Sclerosis, with res…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Tofacitinib in Patients With Amyotrophic Lateral Sclerosis [EARLY_Phase 1]
An early-phase 1 clinical trial is investigating tofacitinib in patients with amyotrophic lateral sclerosis, with the study currently not ye…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Home-based Remote Digital Monitoring to Assess ALS Progression (Track ALS)
The Track ALS study, a home-based remote digital monitoring trial to assess ALS progression, has completed. Sponsor: St. Joseph's Hospital a…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Evaluate the Safety of Neuronata-R® Inj. Suspended With HypoTHermosol® FRS (HTS-FRS) in Patients With ALS [Phase 1]
A Phase 1 trial assessing the safety of Neuronata-R with HypoTHermosol FRS in amyotrophic lateral sclerosis has been suspended; no results a…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: A Prospective Study to Evaluate the Correlation Between Oculometric Measurements and Clinical Endpoints in ALS Patients
A completed prospective study evaluating whether oculometric measurements correlate with clinical endpoints in patients with amyotrophic lat…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Validation Study
A completed validation study evaluating the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) for detecting cognitive impairment in Norw…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: An IIT Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of a Single Intrathecal Injection of SNUG01 in Patients with Amyotrophic Lateral Sclerosis [EARLY_Phase 1]
An IIT Phase 1 study to evaluate the safety, tolerability, and preliminary efficacy of a single intrathecal injection of SNUG01 in patients …
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Dysphagia, QoL and Attitudes Towards PEG in ALS Patients
Clinical trial update for ALS examining dysphagia, quality of life, and attitudes toward PEG; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Contralateral R1 in Amyotrophic Lateral Sclerosis
A clinical trial evaluating Contralateral R1 for Amyotrophic Lateral Sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Study of [11C]CPPC to Assess the Safety and Tolerability in Patients With ALS [Phase 1]
A Phase 1 trial evaluating the safety and tolerability of the PET tracer [11C]CPPC in patients with amyotrophic lateral sclerosis has been t…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: A Biomarker Study to Evaluate MN-166 in Subjects With Amyotrophic Literal Sclerosis (ALS) [Phase 1, Phase 2]
A Phase 1/2 biomarker study evaluating MN-166 (ibudilast) in Amyotrophic Lateral Sclerosis has completed enrollment and posted results.
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Retrospective Study on the Safety and Therapeutic/Improvement Effects of Intravenous Administration of SHED-CM for ALS (SHED-CAH2023)
A completed retrospective study assessing the safety and potential therapeutic effects of intravenous SHED-CM in amyotrophic lateral scleros…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Rapamycin Treatment for ALS [Phase 2]
A Phase 2 trial evaluating rapamycin for amyotrophic lateral sclerosis has completed. The snippet does not include trial results.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis [Phase 1]
A Phase 1 study evaluating the safety, pharmacokinetics, and pharmacodynamics of DNL343 in individuals with Amyotrophic Lateral Sclerosis ha…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Quality of Life Evaluation with the SRI Questionnaire of ALS Patient with Non-invasive Ventilation [NA]
A completed clinical trial evaluating quality of life in amyotrophic lateral sclerosis patients using non-invasive ventilation, assessed wit…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: HEALEY ALS Platform Trial - Regimen E SLS-005 - Trehalose [Phase 2, Phase 3]
Update on the HEALEY ALS Platform Trial Regimen E SLS-005 with trehalose is complete, and results have been posted. The study targets amyotr…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS) [Phase 3]
A Phase 3 safety extension study of oral edaravone in people with amyotrophic lateral sclerosis has completed, with results posted. The upda…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Phase III Trial of AMX0035 for Amyotrophic Lateral Sclerosis Treatment [Phase 3]
Clinical trial update indicates AMX0035 is in a Phase III study for amyotrophic lateral sclerosis that is active but not recruiting.