Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS trial_result · 2015-09-15Clinical Trial Update: Sport Therapy and Osteopathy Manipulative Treatment in ALS [NA]
This document provides an update on a completed clinical trial evaluating sport therapy and osteopathic manipulative treatment for amyotroph…
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea [Phase 2]
Phase 2 trial update showing completion of a toxin-based treatment for sialorrhea in amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2015-07-24Clinical Trial Update: Quantitative Neuromuscular Ultrasonography in Amyotrophic Lateral Sclerosis (ALS)
The document reports the completion of a clinical trial evaluating quantitative neuromuscular ultrasonography in patients with amyotrophic l…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Efficacy of Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)
This document reports the completion of a clinical trial evaluating the efficacy of noninvasive ventilation in amyotrophic lateral sclerosis…
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: A P300 Brain Computer Interface Keyboard to Control Assistive Technology For Use by People With Amyotrophic Lateral Sclerosis [NA]
A completed clinical trial investigated a P300-based brain-computer interface keyboard to help people with amyotrophic lateral sclerosis con…
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: P300 Brain Computer Interface Keyboard to Operate Assistive Technology [Phase 1, Phase 2]
Results from Phase 1 and Phase 2 studies evaluated a P300 brain-computer interface keyboard designed to operate assistive technology. The tr…
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Study of Pioglitazone in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
A Phase 2 study of pioglitazone in amyotrophic lateral sclerosis sponsored by the University of Ulm was terminated.
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Evaluation of a Mechanical Device During Acute Respiratory Failure in Patients With Neuromuscular Disorders [Phase 3]
Phase 3 evaluation of a mechanical device for acute respiratory failure in patients with Duchenne muscular dystrophy and amyotrophic lateral…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls [Phase 3]
Phase 3 clinical trial investigating dopamine and serotonin transporter imaging in patients with amyotrophic lateral sclerosis and control s…
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Amyotrophic Lateral Sclerosis Registry Rhineland-Palatinate
The Amyotrophic Lateral Sclerosis Registry Rhineland-Palatinate has completed, and results were posted on 2015-04-22.
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CLINICAL_TRIALS trial_result · 2015-04-20Clinical Trial Update: Dose Escalation and Safety Study of Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 dose-escalation and safety study of human spinal cord–derived neural stem cell transplantation for amyotrophic lateral sclerosis is …
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Effect of Intrathecal Administration of Hematopoietic Stem Cells in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2, Phase 3]
Clinical trial evaluating intrathecal administration of hematopoietic stem cells in amyotrophic lateral sclerosis has completed both Phase 2…
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CLINICAL_TRIALS trial_result · 2015-04-01Clinical Trial Update: Safety and Tolerability of the Ketogenic Diet in Amyotrophic Lateral Sclerosis (ALS) [Phase 3]
Phase 3 clinical trial studying the safety and tolerability of a ketogenic diet in amyotrophic lateral sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2015-03-27Clinical Trial Update: A Study of the Expression of Nogo and Reticulon Genes in Skeletal Muscle of Patients With Amyotrophic Lateral Sclerosis
The study evaluating expression of Nogo and Reticulon genes in skeletal muscle of patients with amyotrophic lateral sclerosis has been termi…
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CLINICAL_TRIALS trial_result · 2015-03-23Clinical Trial Update: Differential Study of Muscle Transcriptome [NA]
This update notes that a clinical trial examining differential muscle transcriptome in amyotrophic lateral sclerosis, spinal muscular atroph…
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CLINICAL_TRIALS trial_result · 2015-03-11Clinical Trial Update: Neuromuscular Ultrasound in ALS
The clinical trial investigating neuromuscular ultrasound in amyotrophic lateral sclerosis (ALS) by Duke University has completed.
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CLINICAL_TRIALS trial_result · 2015-02-27Clinical Trial Update: High Fat/High Calorie Trial in Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial in amyotrophic lateral sclerosis evaluating a high-fat/high-calorie intervention has completed and results have been …
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: A Clinical Demonstration of EEG Brain-computer Interface for ALS Patients
A completed clinical trial demonstrates an EEG-based brain-computer interface for patients with amyotrophic lateral sclerosis, with results …
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CLINICAL_TRIALS trial_result · 2014-12-04Clinical Trial Update: Safety and Efficacy Study of Creatine and Tamoxifen in Volunteers With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
A Phase 2 trial assessing the safety and efficacy of creatine in combination with tamoxifen in people with amyotrophic lateral sclerosis has…
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CLINICAL_TRIALS trial_result · 2014-11-26Clinical Trial Update: Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 trial evaluating the efficacy and tolerability of Tauroursodeoxycholic acid (TUDCA) in amyotrophic lateral sclerosis has completed a…
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Dexpramipexole and Cimetidine Drug Drug Interaction (DDI) [Phase 1]
Phase 1 results from a drug–drug interaction study evaluating dexpramipexole with cimetidine in amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Dexpramipexole Renal PK Study [Phase 1]
This update reports the completion of a Phase 1 pharmacokinetic study of dexpramipexole, including assessments in individuals with renal ins…
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate) [Phase 1]
Phase 1 study evaluating the effect of dexpramipexole on the QTc interval in healthy volunteers. The trial is sponsored by Knopp Biosciences…
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Dexpramipexole SAD/MAD Study [Phase 1]
This document announces the completion of a Phase 1 SAD/MAD study of dexpramipexole for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Safety/Efficacy Study for the Treatment of Amyotrophic Lateral Sclerosis [Phase 1]
A Phase 1 safety/efficacy trial for amyotrophic lateral sclerosis sponsored by TCA Cellular Therapy has been suspended.