Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS) [Phase 1, Phase 2]
Phase 1/2 trial assessing SOD1 inhibition by pyrimethamine in familial amyotrophic lateral sclerosis has completed; results were posted in 2…
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of MCI-186 (edaravone) for amyotrophic lateral sclerosis has completed, with results post…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Intravenous Injection of Adipose Derived Mesenchymal Stem Cell for ALS [Phase 1]
Phase 1 trial evaluating intravenous adipose-derived mesenchymal stem cells for amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 trial of ozanezumab vs placebo in amyotrophic lateral sclerosis completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Clinical Trial on The Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis (Extension CMN/ELA) [Phase 1, Phase 2]
A clinical trial tested autologous bone marrow stem cell therapy in amyotrophic lateral sclerosis and has completed Phase 1/2 testing.
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: EEG-Based Brain-Computer Interface Project for Individuals With Amyotrophic Lateral Sclerosis (ALS)
Clinical trial update on an EEG-based brain-computer interface project for individuals with amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis [Phase 1]
Phase 1 clinical trial investigating intramuscular infusion of autologous bone marrow stem cells in patients with Amyotrophic Lateral Sclero…
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Clinical Trial Nuedexta in Subjects With ALS [Phase 2]
Phase 2 clinical trial results for Nuedexta in individuals with amyotrophic lateral sclerosis were posted in March 2017.
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: An In-home Study of Brain Computer Interfaces [NA]
This document reports the results of an in-home brain-computer interface study in people with Amyotrophic Lateral Sclerosis. The trial is co…
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease [Phase 2, Phase 3]
This clinical trial update reports on the safety and efficacy of a Cannabis Sativa Extract for spasticity in motor neuron disease and ALS. T…
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Compassionate Use of Ceftriaxone in Patients With Amyotrophic Lateral Sclerosis (ALS)
This document reports a completed compassionate-use clinical trial of ceftriaxone in patients with amyotrophic lateral sclerosis (ALS).
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Cerebrospinal Fluid Repository
The study NCT00714636, sponsored by Drexel University College of Medicine, related to a cerebrospinal fluid repository for amyotrophic later…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: PET Imaging in ALS Patients [NA]
Completed clinical trial investigating PET imaging in patients with amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Nocturnal PtcCO2 Monitoring in Patients With Amyotrophic Lateral Sclerosis (ALS) [NA]
The trial evaluating nocturnal PtcCO2 monitoring in patients with Amyotrophic Lateral Sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
This clinical trial update notes the completion of a Phase 2 study evaluating the safety and tolerability of Acthar in patients with amyotro…
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Non-Invasive Measurement of Gastrointestinal (GI) Motility in Patients With Amyotrophic Lateral Sclerosis (ALS)
This clinical trial update reports on a completed study evaluating non-invasive measurement of gastrointestinal motility in patients with am…
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CLINICAL_TRIALS trial_result · 2017-01-02Clinical Trial Update: Study of Standard Noninvasive Positive Pressure Ventilation (NIPPV) and Low Expiratory Pressure NIPPV in ALS Patients [NA]
A completed clinical study in amyotrophic lateral sclerosis compared standard noninvasive positive pressure ventilation (NIPPV) with low exp…
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis [NA]
This clinical trial update reports completion and posted results of a direct brain interface (ECoG) study in individuals with upper limb par…
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Safety Extension Study of TRO19622 in ALS [Phase 2, Phase 3]
Safety extension study of TRO19622 (olesoxime) in amyotrophic lateral sclerosis has completed Phase 2/3.
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: Study of Rasagiline in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
A Phase 2 clinical trial updating results for rasagiline in patients with amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Diaphragmatic Pacer Placement: Anesthetic Management (DP)
Update on a diaphragmatic pacer placement trial focusing on anesthetic management in spinal cord injury and amyotrophic lateral sclerosis, w…
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CLINICAL_TRIALS trial_result · 2016-08-29Clinical Trial Update: Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Patients With Amyotrophic Lateral Sclerosis [Phase 1]
This clinical trial update describes a Phase 1 study evaluating autologous bone marrow-derived mesenchymal stem cells for treating Amyotroph…
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: A P300 Brain Computer Interface to Operate Power Wheelchair Tilt [NA]
A study evaluating a P300 brain-computer interface to operate a power wheelchair tilt, including healthy participants and patients with amyo…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Safety and Efficacy Study of Autologous Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating autologous bone marrow-derived stem cell treatment for amyotrophic lateral sclerosis has completed with …
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS [Phase 3]
A completed Phase 3 trial evaluating the safety and efficacy of AVP-923 for emotional lability in patients with amyotrophic lateral sclerosi…