Amyotrophic Lateral Sclerosis
📧 Sign up to get email alerts when something new happens for Amyotrophic Lateral Sclerosis.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Retinal Imaging in Neurodegenerative Disease
This clinical trial update notes a Duke University-sponsored study evaluating retinal imaging as a biomarker across multiple neurodegenerati…
-
CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Needs of ALS Patients With C9orf72 Mutation and Their Caregivers
This clinical trial update describes the needs of ALS patients with the C9orf72 mutation and their caregivers, and notes that recruitment fo…
-
CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Quantification of Hsp90 in the Human Brain [NA]
A recruiting clinical study aims to quantify Hsp90 levels in the human brain to explore its role in Parkinson's disease, Alzheimer's disease…
-
CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Healing ALS Registry Observational Study (HAROS)
HAROS is an ongoing observational registry for amyotrophic lateral sclerosis and related motor neuron diseases. Recruitment is currently ope…
-
CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis. [Phase 1, Phase 2]
This document reports an early-stage clinical trial evaluating NB-4746 for amyotrophic lateral sclerosis, which is not yet recruiting.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency [NA]
A clinical trial (NCT06286917) has initiated to evaluate noninvasive ventilation in ALS patients with chronic respiratory insufficiency; spo…
-
CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: UPenn Observational Research Repository on Neurodegenerative Disease
The University of Pennsylvania is conducting an observational research repository for neurodegenerative diseases and is currently recruiting…
-
CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Interest of Measuring P2X4 Receptors on Blood Monocytes as a Diagnostic Marker in Amyotrophic Lateral Sclerosis: P2X4 as a Diagnostic Biomarker for ALS [NA]
This ongoing clinical trial investigates whether measuring P2X4 receptor expression on blood monocytes can diagnose amyotrophic lateral scle…
-
CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: The Importance of Positive Expiratory Pressure Associated With the In-exsufflator in ALS Patients [NA]
A clinical trial evaluating the use of positive expiratory pressure with an in-exsufflator in patients with amyotrophic lateral sclerosis; c…
-
CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Chinese Participants With SOD-1 Amyotrophic Lateral Sclerosis (ALS) [Phase 4]
This clinical trial update describes a Phase 4 study to assess the long-term safety of Tofersen (Qalsody) in Chinese participants with SOD-1…
-
CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Controlling Amyotrophic Lateral Sclerosis Motor Neuron Excitability Study [NA]
Update on the Controlling ALS Motor Neuron Excitability Study shows that the trial is currently recruiting for amyotrophic lateral sclerosis…
-
CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Control Cohort CTRL COH [NA]
A status update for a control cohort in a Hospices Civils de Lyon trial, with recruitment ongoing for Parkinson's disease, amyotrophic later…
-
CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS) [NA]
Clinical trial update for a physiotherapy intervention study in patients with Amyotrophic Lateral Sclerosis, currently recruiting.
-
CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Identifying Biomarkers in ALS Patients Using Neuronal Derived Extracellular Vesicles
A clinical trial is recruiting to identify biomarkers in amyotrophic lateral sclerosis patients using neuronal-derived extracellular vesicle…
-
CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis [EARLY_Phase 1]
An early Phase 1 clinical trial is investigating the effects of psilocybin in patients with amyotrophic lateral sclerosis, and the study is …
-
CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: PREVENT ALL ALS Study
The PREVENT ALL ALS Study is currently recruiting participants to study an intervention for amyotrophic lateral sclerosis at St. Joseph's Ho…
-
CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: ASSESS ALL ALS Study
The ASSESS ALL ALS Study is currently recruiting participants for a trial addressing amyotrophic lateral sclerosis. Sponsor is St. Joseph's …
-
CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Precise Robotically IMplanted Brain-Computer InterfacE [NA]
Neuralink reports a clinical trial update for a robotically implanted brain-computer interface that is currently recruiting for patients wit…
-
CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: This Study Evaluates the Safety, Target Engagement, and Preliminary Efficacy of Galunisertib (TGF-βR1/ALK5 Inhibitor)Combined With Nerandomilast (PDE4 Inhibitor) in GREM2-positive ALS, a Biomarker-defined Subgroup Hypothesized to Reflect Heightened TGF-β/SMAD-driven Astrocytic and Fibrotic Signaling [Phase 2, Phase 3]
This clinical trial update outlines a Phase 2/Phase 3 study evaluating the safety, target engagement, and preliminary efficacy of galunisert…
-
CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Amyotrophic Lateral Sclerosis (ALS) Families Project
Clinical trial update for the Amyotrophic Lateral Sclerosis Families Project. The study is currently recruiting.
-
CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: LONgitudinal and Integrated Evaluation of Biomarkers in reLation to phenotYpe in ALS [NA]
An ongoing clinical trial conducted by Istituto Auxologico Italiano evaluates biomarkers in relation to phenotype in amyotrophic lateral scl…
-
CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Combined Respiratory Training in Persons With ALS [NA]
Clinical trial update for a combined respiratory training program in persons with amyotrophic lateral sclerosis. The study is currently recr…
-
CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Tongue-strengthening Exercises in People With ALS. [NA]
A clinical trial sponsored by Nova Southeastern University is evaluating tongue-strengthening exercises in people with amyotrophic lateral s…
-
CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Muscular Biomarkers in Amyotrophic Lateral Sclerosis [NA]
This update reports a completed clinical trial investigating muscular biomarkers in Amyotrophic Lateral Sclerosis.
-
CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Video-Based Proprioceptive Exercise Program in ALS [NA]
Clinical trial evaluating a video-based proprioceptive exercise program for amyotrophic lateral sclerosis; the study is currently recruiting…