Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Examining Interactions Between PALS and Caregivers [NA]
A clinical trial investigating interactions between people living with ALS and their caregivers, sponsored by Penn State University, current…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders [NA]
Clinical trial update for a study of Ultra-High Resolution PET imaging in aging, neurodegeneration and psychotic disorders; recruitment is o…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS [Phase 2]
A Phase 2 clinical trial evaluating cromolyn (PHENOGENE-1A) for amyotrophic lateral sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients [Phase 1]
Phase 1 trial update for TCD601 (Siplizumab) in newly diagnosed adult amyotrophic lateral sclerosis patients; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Diagnostic Accuracy of SleepImage Technology for Detecting Respiratory Failure in Patients With Amyotrophic Lateral Sclerosis
A clinical trial is evaluating the diagnostic accuracy of SleepImage Technology to detect respiratory failure in patients with amyotrophic l…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation [Phase 3]
Biogen initiated a Phase 3 trial of tofersen (BIIB067) in presymptomatic adults with a confirmed SOD1 mutation for amyotrophic lateral scler…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Dazucorilant in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
Corcept Therapeutics is conducting a Phase 2 trial of dazucorilant in patients with amyotrophic lateral sclerosis, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical Approaches
A clinical trial investigating disease biosignatures in the ALS/FTD spectrum, exploring biological perspectives beyond traditional clinical …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: ALS Diagnosis From a Saliva Sample: a Non-coding RNA Analysis Approach
Clinical trial assessing a saliva-based non-coding RNA analysis method to aid diagnosis of amyotrophic lateral sclerosis.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Adenosine 2A Receptor Antagonism and AIH in ALS [Phase 1, Phase 2]
Clinical trial update on an Adenosine A2A receptor antagonist approach for amyotrophic lateral sclerosis (Phase 1/Phase 2; active not recrui…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Intermediate-size Patient Population Expanded Access Protocol
Spinogenix updated its expanded access protocol for an investigational ALS therapy targeting an intermediate-sized patient population. The u…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Evaluation of a Structurally Suitable Neck Exoskeleton in Patients With Amyotrophic Lateral Sclerosis [NA]
This clinical trial update describes a study evaluating a neck exoskeleton designed for individuals with amyotrophic lateral sclerosis, with…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Impact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealth
This clinical trial update from TidalHealth investigates the relationship between physical functioning and patient-reported outcomes in amyo…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Clinical Procedures to Support Research in ALS
This clinical trial update outlines procedures to support research in amyotrophic lateral sclerosis and related motor neuron diseases, and t…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Phenotype, Genotype and Biomarkers 2
A University of Miami–sponsored clinical trial investigating phenotype, genotype, and biomarkers across motor neuron diseases, including ALS…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: PRE-Symptomatic Studies in Amyotrophic Lateral Sclerosis
This entry reports an active-but-not-recruiting clinical trial focused on pre-symptomatic studies in amyotrophic lateral sclerosis, sponsore…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study
The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study is a University of Miami-sponsored clinical trial currently recr…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Clinical Research in ALS Study
A clinical trial studying amyotrophic lateral sclerosis is currently recruiting, sponsored by the University of Miami.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Spinal Cord Associative Plasticity for ALS [NA]
A clinical trial update shows that Spinal Cord Associative Plasticity for Amyotrophic Lateral Sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study to Evaluate the Safety, Efficacy, and Pharmacodynamics of PLL001 in ALS Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial to evaluate the safety, efficacy, and pharmacodynamics of PLL001 in patients with Amyotrophic Lateral Sclerosis (…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Characterization of Platelet Molecular Profiles in ALS for the Identification of Specific Diagnostic Biomarkers - A Pilot Study
A pilot clinical trial aiming to characterize platelet molecular profiles in amyotrophic lateral sclerosis to identify diagnostic biomarkers…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease [NA]
A clinical trial is evaluating the effects of whole-body electrical muscle stimulation on adults with various neuromuscular diseases and is …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Virtual Reality for Anxiety Management in Persons With Amyotrophic Lateral Sclerosis [NA]
A clinical trial is investigating virtual reality-based anxiety management for people with amyotrophic lateral sclerosis; the study is curre…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS
Clinical trial update on scalable expanded access to ibudilast for amyotrophic lateral sclerosis. The study includes analysis of neurofilame…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Research of Traditional Chinese Medicine Oral Preparation of C. Cicadae in the Treatment of ALS Patients With Elevated Plasma Sphingolipids [Phase 2]
Phase 2 clinical trial protocol evaluating an oral Traditional Chinese Medicine preparation of C. Cicadae for amyotrophic lateral sclerosis …