Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS research · 2018-06-06Clinical Trial Update: Autologous Bone Marrow-Derived Stem Cell Therapy for Motor Neuron Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial update on autologous bone marrow-derived stem cell therapy for motor neuron disease, including ALS and related co…
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CLINICAL_TRIALS research · 2018-06-04Clinical Trial Update: Developing a Discrimination Model to Diagnose ALS [NA]
The University of Michigan completed a study developing a discrimination model to diagnose Amyotrophic Lateral Sclerosis.
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CLINICAL_TRIALS research · 2018-05-25Clinical Trial Update: Multidisciplinary Follow-up of Patients With Amyotrophic Lateral Sclerosis
This document provides an update on a clinical trial studying multidisciplinary follow-up care for patients with amyotrophic lateral scleros…
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CLINICAL_TRIALS research · 2018-04-03Clinical Trial Update: Accurate Test of Limb Isometric Strength (ATLIS) in ALS
This clinical trial update notes the ATLIS test for limb isometric strength in amyotrophic lateral sclerosis, with the current trial status …
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CLINICAL_TRIALS research · 2018-03-26Clinical Trial Update: T-Regulatory Cells in Amyotrophic Lateral Sclerosis [Phase 1]
A Phase 1 clinical trial update evaluating T-regulatory cell therapy for Amyotrophic Lateral Sclerosis.
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CLINICAL_TRIALS research · 2017-12-11Clinical Trial Update: Epidemiology and Genetics of the Amyotrophic Lateral Sclerosis in the French West Indies [NA]
A clinical trial update examining the epidemiology and genetics of amyotrophic lateral sclerosis in the French West Indies.
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CLINICAL_TRIALS research · 2017-11-07Clinical Trial Update: Chromatic Pupillometry to Assess the Melanopsin-Light Pathway in Progressive Supranuclear Palsy
This clinical trial update describes a study using chromatic pupillometry to assess the melanopsin-light pathway in Progressive Supranuclear…
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CLINICAL_TRIALS research · 2017-10-06Clinical Trial Update: Collection of Blood Samples for DNA in Motor Neuron Disease
Update on a clinical trial collecting blood samples for DNA to study motor neuron diseases; no treatment results are reported in this docume…
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CLINICAL_TRIALS research · 2017-10-06Clinical Trial Update: Amyotrophic Lateral Sclerosis and the Innate Immune System
A Denmark-based clinical trial sponsored by Rigshospitalet is currently recruiting to investigate the role of the innate immune system in am…
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CLINICAL_TRIALS research · 2017-08-08Clinical Trial Update: A Programme for Amyotrophic Lateral Sclerosis Care in Europe
This document reports an ongoing European program designed to improve care for people with amyotrophic lateral sclerosis (ALS) and motor neu…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Exposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis
A completed clinical trial investigates whether exposure to environmental neurotoxins is a risk factor for amyotrophic lateral sclerosis (AL…
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CLINICAL_TRIALS research · 2017-05-30Clinical Trial Update: A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Massachusetts General Hospital completed a longitudinal study investigating biomarkers in amyotrophic lateral sclerosis, contributing data o…
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CLINICAL_TRIALS research · 2017-04-26Clinical Trial Update: Trial of Amivita in Amyotrophic Lateral Sclerosis [NA]
A clinical trial update for Amivita in amyotrophic lateral sclerosis, with the trial status currently unknown.
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CLINICAL_TRIALS research · 2017-04-13Clinical Trial Update: Virtual Task in Amyotrophic Lateral Sclerosis [NA]
Completed clinical trial update from the University of Sao Paulo on a virtual task study in amyotrophic lateral sclerosis.
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CLINICAL_TRIALS research · 2017-03-23Clinical Trial Update: Longitudinal Study of Outcomes Measures in ALS Trials
This update reports on a longitudinal study of outcome measures used in amyotrophic lateral sclerosis trials to evaluate and standardize how…
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CLINICAL_TRIALS research · 2017-01-06Clinical Trial Update: Amyotrophic Lateral Sclerosis (ALS) Tissue Donation Program
The ALS tissue donation program trial conducted by Drexel University College of Medicine has completed. The study status is listed as COMPLE…
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CLINICAL_TRIALS research · 2016-11-23Clinical Trial Update: Bioenergetics and Protein Metabolism in Sporadic Amyotrophic Lateral Sclerosis [EARLY_Phase 1]
An early-phase 1 clinical trial at University Hospital Angers is investigating bioenergetics and protein metabolism in sporadic amyotrophic …
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CLINICAL_TRIALS research · 2016-10-26Clinical Trial Update: A Registry-Based Clinical Trial of Pimozide in Patients With Neuromuscular Junction Transmission Dysfunction Due to ALS [Phase 2]
Phase 2 registry-based clinical trial evaluating pimozide for neuromuscular junction transmission dysfunction in amyotrophic lateral scleros…
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CLINICAL_TRIALS research · 2016-09-28Clinical Trial Update: Study of Two Intrathecal Doses of Autologous Mesenchymal Stem Cells for Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
This entry describes a Phase 1/2 clinical trial evaluating two intrathecal doses of autologous mesenchymal stem cells in individuals with am…
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CLINICAL_TRIALS research · 2016-08-29Clinical Trial Update: Therapeutic Treatment of Amyotrophic Lateral Sclerosis [Phase 1]
This entry reports a Phase 1 clinical trial investigating a therapeutic treatment for amyotrophic lateral sclerosis, with the study status c…
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CLINICAL_TRIALS research · 2016-08-22Clinical Trial Update: Noninvasive Assessment of Neuronal Damage by MRI Sodium ( 23Na ) in Amyotrophic Lateral Sclerosis [NA]
This document summarizes a clinical trial evaluating noninvasive MRI sodium-23 imaging to assess neuronal damage in amyotrophic lateral scle…
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CLINICAL_TRIALS research · 2016-05-03Clinical Trial Update: A Study to Evaluate the Performance of a Diagnostic Test in ALS
This document reports a study to evaluate the performance of a diagnostic test for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Tongue Strength in Amyotrophic Lateral Sclerosis (ALS) [NA]
A clinical trial update examining tongue strength in individuals with amyotrophic lateral sclerosis (ALS); the current trial status is not d…
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CLINICAL_TRIALS research · 2015-12-22Clinical Trial Update: Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation [Phase 3]
A Phase 3 trial evaluating phrenic stimulation for respiratory insufficiency in amyotrophic lateral sclerosis was terminated.
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CLINICAL_TRIALS research · 2015-12-07Clinical Trial Update: Influence of the Vitamin D Blood Levels on the Amyotrophic Lateral Sclerosis Phenotype [NA]
This entry notes the completed study exploring how Vitamin D blood levels may influence the phenotype of amyotrophic lateral sclerosis.